KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF845
Full Name:
Zinc finger protein 845
Alias:
Type:
Mass (Da):
113133
Number AA:
970
UniProt ID:
Q96IR2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
R
D
V
A
I
E
F
S
Q
E
E
W
K
C
L
Site 2
Y33
D
P
A
Q
R
T
L
Y
R
D
V
M
L
E
N
Site 3
Y41
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
D
Site 4
S46
E
N
Y
R
N
L
V
S
L
D
I
S
S
K
C
Site 5
S50
N
L
V
S
L
D
I
S
S
K
C
M
M
K
E
Site 6
S59
K
C
M
M
K
E
F
S
S
T
A
Q
G
N
T
Site 7
T61
M
M
K
E
F
S
S
T
A
Q
G
N
T
E
V
Site 8
T71
G
N
T
E
V
I
H
T
G
T
L
Q
R
H
E
Site 9
S108
W
K
E
D
E
R
N
S
H
E
A
P
M
T
E
Site 10
T114
N
S
H
E
A
P
M
T
E
I
K
Q
L
T
G
Site 11
S142
P
I
K
D
Q
L
G
S
S
F
H
S
H
L
P
Site 12
S143
I
K
D
Q
L
G
S
S
F
H
S
H
L
P
E
Site 13
S146
Q
L
G
S
S
F
H
S
H
L
P
E
L
H
M
Site 14
T156
P
E
L
H
M
F
Q
T
Q
G
K
I
G
N
Q
Site 15
S167
I
G
N
Q
V
E
K
S
I
N
S
A
S
L
V
Site 16
S170
Q
V
E
K
S
I
N
S
A
S
L
V
S
T
S
Site 17
S172
E
K
S
I
N
S
A
S
L
V
S
T
S
Q
R
Site 18
T176
N
S
A
S
L
V
S
T
S
Q
R
I
S
C
R
Site 19
S177
S
A
S
L
V
S
T
S
Q
R
I
S
C
R
P
Site 20
S181
V
S
T
S
Q
R
I
S
C
R
P
K
T
H
I
Site 21
T186
R
I
S
C
R
P
K
T
H
I
S
K
N
Y
G
Site 22
Y192
K
T
H
I
S
K
N
Y
G
N
N
F
L
N
S
Site 23
T203
F
L
N
S
S
L
L
T
Q
K
Q
E
V
H
M
Site 24
S214
E
V
H
M
R
E
K
S
F
Q
C
N
E
S
G
Site 25
S220
K
S
F
Q
C
N
E
S
G
K
A
F
N
Y
S
Site 26
Y226
E
S
G
K
A
F
N
Y
S
S
V
L
R
K
H
Site 27
S227
S
G
K
A
F
N
Y
S
S
V
L
R
K
H
Q
Site 28
S228
G
K
A
F
N
Y
S
S
V
L
R
K
H
Q
I
Site 29
Y243
I
H
L
G
A
K
Q
Y
K
C
D
V
C
G
K
Site 30
Y257
K
V
F
N
Q
K
R
Y
L
A
C
H
R
R
C
Site 31
T266
A
C
H
R
R
C
H
T
G
K
K
P
Y
K
C
Site 32
T279
K
C
N
D
C
G
K
T
F
S
Q
E
L
T
L
Site 33
S281
N
D
C
G
K
T
F
S
Q
E
L
T
L
T
C
Site 34
T285
K
T
F
S
Q
E
L
T
L
T
C
H
H
R
L
Site 35
T294
T
C
H
H
R
L
H
T
G
E
K
H
Y
K
C
Site 36
Y299
L
H
T
G
E
K
H
Y
K
C
S
E
C
G
K
Site 37
T307
K
C
S
E
C
G
K
T
F
S
R
N
S
A
L
Site 38
S309
S
E
C
G
K
T
F
S
R
N
S
A
L
V
I
Site 39
S312
G
K
T
F
S
R
N
S
A
L
V
I
H
K
A
Site 40
T335
K
C
N
E
C
G
K
T
F
S
Q
T
S
Y
L
Site 41
S337
N
E
C
G
K
T
F
S
Q
T
S
Y
L
V
Y
Site 42
S340
G
K
T
F
S
Q
T
S
Y
L
V
Y
H
R
R
Site 43
Y341
K
T
F
S
Q
T
S
Y
L
V
Y
H
R
R
L
Site 44
Y344
S
Q
T
S
Y
L
V
Y
H
R
R
L
H
T
G
Site 45
T350
V
Y
H
R
R
L
H
T
G
E
K
P
Y
K
C
Site 46
S365
E
E
C
D
K
A
F
S
F
K
S
N
L
E
R
Site 47
S368
D
K
A
F
S
F
K
S
N
L
E
R
H
R
K
Site 48
S389
P
Y
K
C
N
E
C
S
R
T
F
S
R
K
S
Site 49
T391
K
C
N
E
C
S
R
T
F
S
R
K
S
S
L
Site 50
S393
N
E
C
S
R
T
F
S
R
K
S
S
L
T
R
Site 51
S396
S
R
T
F
S
R
K
S
S
L
T
R
H
R
R
Site 52
S397
R
T
F
S
R
K
S
S
L
T
R
H
R
R
L
Site 53
T399
F
S
R
K
S
S
L
T
R
H
R
R
L
H
T
Site 54
T406
T
R
H
R
R
L
H
T
G
E
K
P
Y
K
C
Site 55
T419
K
C
N
D
C
G
K
T
F
S
Q
M
S
S
L
Site 56
S421
N
D
C
G
K
T
F
S
Q
M
S
S
L
V
Y
Site 57
S425
K
T
F
S
Q
M
S
S
L
V
Y
H
R
R
L
Site 58
Y428
S
Q
M
S
S
L
V
Y
H
R
R
L
H
T
G
Site 59
S449
E
E
C
D
E
A
F
S
F
K
S
N
L
E
R
Site 60
S452
D
E
A
F
S
F
K
S
N
L
E
R
H
R
R
Site 61
T462
E
R
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 62
T475
K
C
N
D
C
G
K
T
F
S
Q
T
S
S
L
Site 63
S477
N
D
C
G
K
T
F
S
Q
T
S
S
L
V
Y
Site 64
T479
C
G
K
T
F
S
Q
T
S
S
L
V
Y
H
R
Site 65
S481
K
T
F
S
Q
T
S
S
L
V
Y
H
R
R
L
Site 66
Y484
S
Q
T
S
S
L
V
Y
H
R
R
L
H
T
G
Site 67
S508
D
E
A
F
S
F
K
S
N
L
E
R
H
R
I
Site 68
Y523
I
H
T
G
E
K
L
Y
K
C
N
E
C
G
K
Site 69
T531
K
C
N
E
C
G
K
T
F
S
R
K
S
S
L
Site 70
S533
N
E
C
G
K
T
F
S
R
K
S
S
L
T
R
Site 71
S536
G
K
T
F
S
R
K
S
S
L
T
R
H
C
R
Site 72
S537
K
T
F
S
R
K
S
S
L
T
R
H
C
R
L
Site 73
T539
F
S
R
K
S
S
L
T
R
H
C
R
L
H
T
Site 74
T546
T
R
H
C
R
L
H
T
G
E
K
P
Y
Q
C
Site 75
Y551
L
H
T
G
E
K
P
Y
Q
C
N
E
C
G
K
Site 76
S564
G
K
A
F
R
G
Q
S
A
L
I
Y
H
Q
A
Site 77
Y568
R
G
Q
S
A
L
I
Y
H
Q
A
I
H
G
I
Site 78
Y579
I
H
G
I
G
K
L
Y
K
C
N
D
C
H
Q
Site 79
Y607
I
H
N
E
E
R
S
Y
K
C
N
R
C
G
K
Site 80
Y621
K
F
F
R
H
R
S
Y
L
A
V
H
W
R
T
Site 81
S645
E
E
C
D
E
A
F
S
F
K
S
N
L
Q
R
Site 82
S648
D
E
A
F
S
F
K
S
N
L
Q
R
H
R
R
Site 83
T658
Q
R
H
R
R
I
H
T
G
E
K
P
Y
R
C
Site 84
Y663
I
H
T
G
E
K
P
Y
R
C
N
E
C
G
K
Site 85
T671
R
C
N
E
C
G
K
T
F
S
R
K
S
Y
L
Site 86
S673
N
E
C
G
K
T
F
S
R
K
S
Y
L
T
C
Site 87
S676
G
K
T
F
S
R
K
S
Y
L
T
C
H
R
R
Site 88
Y677
K
T
F
S
R
K
S
Y
L
T
C
H
R
R
L
Site 89
T679
F
S
R
K
S
Y
L
T
C
H
R
R
L
H
T
Site 90
T686
T
C
H
R
R
L
H
T
G
E
K
P
Y
K
C
Site 91
Y691
L
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 92
T699
K
C
N
E
C
G
K
T
F
G
R
N
S
A
L
Site 93
S704
G
K
T
F
G
R
N
S
A
L
I
I
H
K
A
Site 94
Y719
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 95
S729
N
E
C
G
K
A
F
S
Q
K
S
S
L
T
C
Site 96
S732
G
K
A
F
S
Q
K
S
S
L
T
C
H
L
R
Site 97
S733
K
A
F
S
Q
K
S
S
L
T
C
H
L
R
L
Site 98
T735
F
S
Q
K
S
S
L
T
C
H
L
R
L
H
T
Site 99
T742
T
C
H
L
R
L
H
T
G
E
K
P
Y
K
C
Site 100
S757
E
E
C
D
K
V
F
S
R
K
S
S
L
E
K
Site 101
S760
D
K
V
F
S
R
K
S
S
L
E
K
H
R
R
Site 102
S761
K
V
F
S
R
K
S
S
L
E
K
H
R
R
I
Site 103
T770
E
K
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 104
S788
D
K
A
F
G
R
D
S
H
L
A
Q
H
T
R
Site 105
T798
A
Q
H
T
R
I
H
T
G
E
K
P
Y
K
C
Site 106
S816
G
K
N
F
R
H
N
S
A
L
V
I
H
K
A
Site 107
Y831
I
H
S
G
E
K
P
Y
K
C
N
E
C
G
K
Site 108
S844
G
K
T
F
R
H
N
S
A
L
E
I
H
K
A
Site 109
Y859
I
H
T
G
E
K
P
Y
K
C
S
E
C
G
K
Site 110
S875
F
N
R
K
A
N
L
S
R
H
H
R
L
H
T
Site 111
T882
S
R
H
H
R
L
H
T
G
E
K
P
Y
K
C
Site 112
Y887
L
H
T
G
E
K
P
Y
K
C
N
K
C
G
K
Site 113
T910
A
C
H
H
R
I
H
T
G
E
K
P
Y
K
C
Site 114
S928
G
K
T
F
R
H
N
S
V
L
V
I
H
K
T
Site 115
T935
S
V
L
V
I
H
K
T
I
H
T
G
E
K
P
Site 116
T966
A
R
H
H
R
I
H
T
G
K
K
H
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation