KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NGLY1
Full Name:
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Alias:
N-glycanase 1;Peptide:N-glycanase
Type:
Mass (Da):
74372
Number AA:
654
UniProt ID:
Q96IV0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0000224
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006516
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
V
A
E
L
C
Q
N
T
P
E
T
F
L
E
A
Site 2
T27
L
C
Q
N
T
P
E
T
F
L
E
A
S
K
L
Site 3
Y51
R
N
P
N
D
E
K
Y
R
S
I
R
I
G
N
Site 4
S53
P
N
D
E
K
Y
R
S
I
R
I
G
N
T
A
Site 5
S62
R
I
G
N
T
A
F
S
T
R
L
L
P
V
R
Site 6
T85
M
G
F
E
E
G
E
T
H
L
I
F
P
K
K
Site 7
S110
D
L
I
A
I
E
R
S
S
R
L
D
G
S
N
Site 8
S111
L
I
A
I
E
R
S
S
R
L
D
G
S
N
K
Site 9
S116
R
S
S
R
L
D
G
S
N
K
S
H
K
V
K
Site 10
S119
R
L
D
G
S
N
K
S
H
K
V
K
S
S
Q
Site 11
S124
N
K
S
H
K
V
K
S
S
Q
Q
P
A
A
S
Site 12
S125
K
S
H
K
V
K
S
S
Q
Q
P
A
A
S
T
Site 13
S131
S
S
Q
Q
P
A
A
S
T
Q
L
P
T
T
P
Site 14
T132
S
Q
Q
P
A
A
S
T
Q
L
P
T
T
P
S
Site 15
T136
A
A
S
T
Q
L
P
T
T
P
S
S
N
P
S
Site 16
T137
A
S
T
Q
L
P
T
T
P
S
S
N
P
S
G
Site 17
S139
T
Q
L
P
T
T
P
S
S
N
P
S
G
L
N
Site 18
S140
Q
L
P
T
T
P
S
S
N
P
S
G
L
N
Q
Site 19
S143
T
T
P
S
S
N
P
S
G
L
N
Q
H
T
R
Site 20
S156
T
R
N
R
Q
G
Q
S
S
D
P
P
S
A
S
Site 21
S157
R
N
R
Q
G
Q
S
S
D
P
P
S
A
S
T
Site 22
S161
G
Q
S
S
D
P
P
S
A
S
T
V
A
A
D
Site 23
S163
S
S
D
P
P
S
A
S
T
V
A
A
D
S
A
Site 24
T164
S
D
P
P
S
A
S
T
V
A
A
D
S
A
I
Site 25
Y185
N
I
Q
H
V
L
V
Y
E
N
P
A
L
Q
E
Site 26
S207
V
Q
E
L
K
R
K
S
Q
E
K
L
S
R
A
Site 27
S212
R
K
S
Q
E
K
L
S
R
A
R
K
L
D
K
Site 28
S259
K
C
G
G
Q
T
R
S
R
D
R
S
L
L
P
Site 29
S263
Q
T
R
S
R
D
R
S
L
L
P
S
D
D
E
Site 30
S267
R
D
R
S
L
L
P
S
D
D
E
L
K
W
G
Site 31
Y282
A
K
E
V
E
D
H
Y
C
D
A
C
Q
F
S
Site 32
Y295
F
S
N
R
F
P
R
Y
N
N
P
E
K
L
L
Site 33
T304
N
P
E
K
L
L
E
T
R
C
G
R
C
G
E
Site 34
Y329
A
V
G
F
E
A
R
Y
V
W
D
Y
T
D
H
Site 35
Y365
V
C
D
K
P
L
L
Y
E
I
G
W
G
K
K
Site 36
Y375
G
W
G
K
K
L
S
Y
V
I
A
F
S
K
D
Site 37
T403
E
E
V
I
A
R
R
T
K
V
K
E
A
L
L
Site 38
T413
K
E
A
L
L
R
D
T
I
N
G
L
N
K
Q
Site 39
S426
K
Q
R
Q
L
F
L
S
E
N
R
R
K
E
L
Site 40
S446
V
E
L
V
E
F
I
S
P
K
T
P
K
P
G
Site 41
T449
V
E
F
I
S
P
K
T
P
K
P
G
E
L
G
Site 42
S460
G
E
L
G
G
R
I
S
G
S
V
A
W
R
V
Site 43
T479
M
G
L
Q
R
K
E
T
L
F
I
P
C
E
N
Site 44
Y497
S
K
Q
L
H
L
C
Y
N
I
V
K
D
R
Y
Site 45
Y504
Y
N
I
V
K
D
R
Y
V
R
V
S
N
N
N
Site 46
S508
K
D
R
Y
V
R
V
S
N
N
N
Q
T
I
S
Site 47
Y539
E
T
D
W
H
M
V
Y
L
A
R
K
E
G
S
Site 48
S547
L
A
R
K
E
G
S
S
F
A
Y
I
S
W
K
Site 49
Y550
K
E
G
S
S
F
A
Y
I
S
W
K
F
E
C
Site 50
S566
S
V
G
L
K
V
D
S
I
S
I
R
T
S
S
Site 51
S568
G
L
K
V
D
S
I
S
I
R
T
S
S
Q
T
Site 52
S572
D
S
I
S
I
R
T
S
S
Q
T
F
Q
T
G
Site 53
S573
S
I
S
I
R
T
S
S
Q
T
F
Q
T
G
T
Site 54
T575
S
I
R
T
S
S
Q
T
F
Q
T
G
T
V
E
Site 55
T580
S
Q
T
F
Q
T
G
T
V
E
W
K
L
R
S
Site 56
T589
E
W
K
L
R
S
D
T
A
Q
V
E
L
T
G
Site 57
T595
D
T
A
Q
V
E
L
T
G
D
N
S
L
H
S
Site 58
S599
V
E
L
T
G
D
N
S
L
H
S
Y
A
D
F
Site 59
S602
T
G
D
N
S
L
H
S
Y
A
D
F
S
G
A
Site 60
Y603
G
D
N
S
L
H
S
Y
A
D
F
S
G
A
T
Site 61
S636
H
T
Q
L
F
R
Q
S
L
N
D
H
E
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation