PhosphoNET

           
Protein Info 
   
Short Name:  ABCC11
Full Name:  ATP-binding cassette sub-family C member 11
Alias:  Multidrug resistance-associated protein 8
Type: 
Mass (Da):  154301
Number AA:  1382
UniProt ID:  Q96J66
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12RTYWVPNSSGGLVNR
Site 2Y33DMVSGLIYKTYTLQD
Site 3Y36SGLIYKTYTLQDGPW
Site 4T37GLIYKTYTLQDGPWS
Site 5S44TLQDGPWSQQERNPE
Site 6Y64AVPPWGKYDAALRTM
Site 7T70KYDAALRTMIPFRPK
Site 8S107LTPLMIQSLRSRLDE
Site 9T116RSRLDENTIPPLSVH
Site 10S121ENTIPPLSVHDASDK
Site 11S142RLWEEEVSRRGIEKA
Site 12S223KSLSFSSSWIINQRT
Site 13T342SDQRIRVTSEVLTCI
Site 14S343DQRIRVTSEVLTCIK
Site 15Y355CIKLIKMYTWEKPFA
Site 16T356IKLIKMYTWEKPFAK
Site 17T413TSLKLKLTASMAFSM
Site 18S423MAFSMLASLNLLRLS
Site 19S444AVKGLTNSKSAVMRF
Site 20S446KGLTNSKSAVMRFKK
Site 21S459KKFFLQESPVFYVQT
Site 22Y463LQESPVFYVQTLQDP
Site 23T486ATLSWQQTCPGIVNG
Site 24S504LERNGHASEGMTRPR
Site 25S522GPEEEGNSLGPELHK
Site 26S548GVCGNTGSGKSSLLS
Site 27S552NTGSGKSSLLSAILE
Site 28S555SGKSSLLSAILEEMH
Site 29S573GSVGVQGSLAYVPQQ
Site 30Y603GAYDKARYLQVLHCC
Site 31S635GERGLNLSGGQKQRI
Site 32S643GGQKQRISLARAVYS
Site 33Y655VYSDRQIYLLDDPLS
Site 34T680FEECIKKTLRGKTVV
Site 35T685KKTLRGKTVVLVTHQ
Site 36Y726LMQKKGKYAQLIQKM
Site 37S762ESQALATSLEESLNG
Site 38S766LATSLEESLNGNAVP
Site 39T778AVPEHQLTQEEEMEE
Site 40S787EEEMEEGSLSWRVYH
Site 41Y793GSLSWRVYHHYIQAA
Site 42Y796SWRVYHHYIQAAGGY
Site 43S835SYWLEQGSGTNSSRE
Site 44S839EQGSGTNSSRESNGT
Site 45S840QGSGTNSSRESNGTM
Site 46S843GTNSSRESNGTMADL
Site 47T846SSRESNGTMADLGNI
Site 48Y862DNPQLSFYQLVYGLN
Site 49S892TKVTRKASTALHNKL
Site 50Y993VFKRLENYSRSPLFS
Site 51S994FKRLENYSRSPLFSH
Site 52S996RLENYSRSPLFSHIL
Site 53S1000YSRSPLFSHILNSLQ
Site 54S1011NSLQGLSSIHVYGKT
Site 55Y1015GLSSIHVYGKTEDFI
Site 56T1018SIHVYGKTEDFISQF
Site 57S1023GKTEDFISQFKRLTD
Site 58T1029ISQFKRLTDAQNNYL
Site 59T1106LETEAQFTAVERILQ
Site 60Y1146GEIIFQDYHMKYRDN
Site 61Y1150FQDYHMKYRDNTPTV
Site 62T1154HMKYRDNTPTVLHGI
Site 63T1156KYRDNTPTVLHGINL
Site 64T1177VVGIVGRTGSGKSSL
Site 65S1179GIVGRTGSGKSSLGM
Site 66S1182GRTGSGKSSLGMALF
Site 67S1183RTGSGKSSLGMALFR
Site 68S1216IGLEDLRSKLSVIPQ
Site 69S1219EDLRSKLSVIPQDPV
Site 70T1254IWDALERTFLTKAIS
Site 71T1257ALERTFLTKAISKFP
Site 72S1261TFLTKAISKFPKKLH
Site 73T1269KFPKKLHTDVVENGG
Site 74S1279VENGGNFSVGERQLL
Site 75S1307LIDEATASIDMETDT
Site 76T1312TASIDMETDTLIQRT
Site 77T1314SIDMETDTLIQRTIR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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