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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRIG1
Full Name:
Leucine-rich repeats and immunoglobulin-like domains protein 1
Alias:
DKFZP586O1624; Leucine-rich repeat protein LRIG1; Leucine-rich repeats and immunoglobulin-like domains 1; LIG1; LIG-1; Ortholog of mouse integral membrane glycoprotein LIG-1
Type:
Protein kinase, regulatory subunit
Mass (Da):
119113
Number AA:
1093
UniProt ID:
Q96JA1
International Prot ID:
IPI00000775
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S259
D
G
A
F
W
G
L
S
K
M
H
V
L
H
L
Site 2
S331
E
E
S
L
A
E
L
S
S
L
S
V
L
R
L
Site 3
S332
E
S
L
A
E
L
S
S
L
S
V
L
R
L
S
Site 4
S334
L
A
E
L
S
S
L
S
V
L
R
L
S
H
N
Site 5
T594
Y
S
H
K
A
R
L
T
V
N
V
L
P
S
F
Site 6
S600
L
T
V
N
V
L
P
S
F
T
K
T
P
H
D
Site 7
T602
V
N
V
L
P
S
F
T
K
T
P
H
D
I
T
Site 8
Y816
L
V
W
V
C
I
I
Y
Q
T
R
K
K
S
E
Site 9
S822
I
Y
Q
T
R
K
K
S
E
E
Y
S
V
T
N
Site 10
S826
R
K
K
S
E
E
Y
S
V
T
N
T
D
E
T
Site 11
T828
K
S
E
E
Y
S
V
T
N
T
D
E
T
V
V
Site 12
T830
E
E
Y
S
V
T
N
T
D
E
T
V
V
P
P
Site 13
T833
S
V
T
N
T
D
E
T
V
V
P
P
D
V
P
Site 14
S841
V
V
P
P
D
V
P
S
Y
L
S
S
Q
G
T
Site 15
Y842
V
P
P
D
V
P
S
Y
L
S
S
Q
G
T
L
Site 16
S844
P
D
V
P
S
Y
L
S
S
Q
G
T
L
S
D
Site 17
S845
D
V
P
S
Y
L
S
S
Q
G
T
L
S
D
R
Site 18
T848
S
Y
L
S
S
Q
G
T
L
S
D
R
Q
E
T
Site 19
S850
L
S
S
Q
G
T
L
S
D
R
Q
E
T
V
V
Site 20
T855
T
L
S
D
R
Q
E
T
V
V
R
T
E
G
G
Site 21
S871
Q
A
N
G
H
I
E
S
N
G
V
C
P
R
D
Site 22
S880
G
V
C
P
R
D
A
S
H
F
P
E
P
D
T
Site 23
T887
S
H
F
P
E
P
D
T
H
S
V
A
C
R
Q
Site 24
S889
F
P
E
P
D
T
H
S
V
A
C
R
Q
P
K
Site 25
T917
A
M
E
K
A
E
G
T
P
G
P
H
K
M
E
Site 26
Y941
C
N
T
E
V
D
C
Y
S
R
G
Q
A
F
H
Site 27
S953
A
F
H
P
Q
P
V
S
R
D
S
A
Q
P
S
Site 28
S956
P
Q
P
V
S
R
D
S
A
Q
P
S
A
P
N
Site 29
S960
S
R
D
S
A
Q
P
S
A
P
N
G
P
E
P
Site 30
S970
N
G
P
E
P
G
G
S
D
Q
E
H
S
P
H
Site 31
S975
G
G
S
D
Q
E
H
S
P
H
H
Q
C
S
R
Site 32
S981
H
S
P
H
H
Q
C
S
R
T
A
A
G
S
C
Site 33
T983
P
H
H
Q
C
S
R
T
A
A
G
S
C
P
E
Site 34
S987
C
S
R
T
A
A
G
S
C
P
E
C
Q
G
S
Site 35
S994
S
C
P
E
C
Q
G
S
L
Y
P
S
N
H
D
Site 36
Y996
P
E
C
Q
G
S
L
Y
P
S
N
H
D
R
M
Site 37
S998
C
Q
G
S
L
Y
P
S
N
H
D
R
M
L
T
Site 38
T1005
S
N
H
D
R
M
L
T
A
V
K
K
K
P
M
Site 39
S1014
V
K
K
K
P
M
A
S
L
D
G
K
G
D
S
Site 40
S1021
S
L
D
G
K
G
D
S
S
W
T
L
A
R
L
Site 41
S1022
L
D
G
K
G
D
S
S
W
T
L
A
R
L
Y
Site 42
T1024
G
K
G
D
S
S
W
T
L
A
R
L
Y
H
P
Site 43
Y1029
S
W
T
L
A
R
L
Y
H
P
D
S
T
E
L
Site 44
S1033
A
R
L
Y
H
P
D
S
T
E
L
Q
P
A
S
Site 45
T1034
R
L
Y
H
P
D
S
T
E
L
Q
P
A
S
S
Site 46
S1040
S
T
E
L
Q
P
A
S
S
L
T
S
G
S
P
Site 47
S1041
T
E
L
Q
P
A
S
S
L
T
S
G
S
P
E
Site 48
S1044
Q
P
A
S
S
L
T
S
G
S
P
E
R
A
E
Site 49
S1046
A
S
S
L
T
S
G
S
P
E
R
A
E
A
Q
Site 50
Y1054
P
E
R
A
E
A
Q
Y
L
L
V
S
N
G
H
Site 51
S1069
L
P
K
A
C
D
A
S
P
E
S
T
P
L
T
Site 52
S1072
A
C
D
A
S
P
E
S
T
P
L
T
G
Q
L
Site 53
T1073
C
D
A
S
P
E
S
T
P
L
T
G
Q
L
P
Site 54
T1076
S
P
E
S
T
P
L
T
G
Q
L
P
G
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation