KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RGPR-p117
Full Name:
Protein transport protein Sec16B
Alias:
Leucine zipper transcription regulator 2; LZTR2; PGPR-p117; Protein SEC16 homolog B; Regucalcin gene promoter region-related protein p117; Regucalcin gene promotor region related protein; RGPR; SEC16 B
Type:
Mass (Da):
116604
Number AA:
1060
UniProt ID:
Q96JE7
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
GO:0019898
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
R
G
K
A
T
A
P
S
K
D
P
D
R
G
F
Site 2
S55
Q
W
Q
D
N
R
G
S
P
Q
P
Q
Q
E
P
Site 3
Y72
D
H
Q
Q
Q
P
H
Y
A
S
R
P
G
D
W
Site 4
Y88
Q
P
V
S
G
V
D
Y
Y
E
G
G
Y
R
N
Site 5
Y89
P
V
S
G
V
D
Y
Y
E
G
G
Y
R
N
Q
Site 6
Y98
G
G
Y
R
N
Q
L
Y
S
R
P
G
Y
E
N
Site 7
S99
G
Y
R
N
Q
L
Y
S
R
P
G
Y
E
N
S
Site 8
Y103
Q
L
Y
S
R
P
G
Y
E
N
S
Y
Q
S
Y
Site 9
S106
S
R
P
G
Y
E
N
S
Y
Q
S
Y
Q
S
P
Site 10
Y107
R
P
G
Y
E
N
S
Y
Q
S
Y
Q
S
P
T
Site 11
S109
G
Y
E
N
S
Y
Q
S
Y
Q
S
P
T
M
R
Site 12
Y110
Y
E
N
S
Y
Q
S
Y
Q
S
P
T
M
R
E
Site 13
S112
N
S
Y
Q
S
Y
Q
S
P
T
M
R
E
E
Y
Site 14
T114
Y
Q
S
Y
Q
S
P
T
M
R
E
E
Y
A
Y
Site 15
Y119
S
P
T
M
R
E
E
Y
A
Y
G
S
Y
Y
Y
Site 16
Y121
T
M
R
E
E
Y
A
Y
G
S
Y
Y
Y
H
G
Site 17
Y124
E
E
Y
A
Y
G
S
Y
Y
Y
H
G
H
P
Q
Site 18
Y125
E
Y
A
Y
G
S
Y
Y
Y
H
G
H
P
Q
W
Site 19
Y126
Y
A
Y
G
S
Y
Y
Y
H
G
H
P
Q
W
L
Site 20
S143
E
R
V
P
R
Q
R
S
P
Y
I
W
H
E
D
Site 21
Y145
V
P
R
Q
R
S
P
Y
I
W
H
E
D
Y
R
Site 22
Y151
P
Y
I
W
H
E
D
Y
R
E
Q
K
Y
L
D
Site 23
Y156
E
D
Y
R
E
Q
K
Y
L
D
E
H
H
Y
E
Site 24
Y162
K
Y
L
D
E
H
H
Y
E
N
Q
H
S
P
F
Site 25
S167
H
H
Y
E
N
Q
H
S
P
F
G
T
N
S
E
Site 26
T171
N
Q
H
S
P
F
G
T
N
S
E
T
H
F
Q
Site 27
S173
H
S
P
F
G
T
N
S
E
T
H
F
Q
S
N
Site 28
T175
P
F
G
T
N
S
E
T
H
F
Q
S
N
S
R
Site 29
S179
N
S
E
T
H
F
Q
S
N
S
R
N
P
C
K
Site 30
S188
S
R
N
P
C
K
D
S
P
A
S
N
S
G
Q
Site 31
S191
P
C
K
D
S
P
A
S
N
S
G
Q
E
W
P
Site 32
S205
P
G
E
L
F
P
G
S
L
L
A
E
A
Q
K
Site 33
S216
E
A
Q
K
N
K
P
S
L
A
S
E
S
N
L
Site 34
S219
K
N
K
P
S
L
A
S
E
S
N
L
L
Q
Q
Site 35
S229
N
L
L
Q
Q
R
E
S
G
L
S
S
S
S
Y
Site 36
S232
Q
Q
R
E
S
G
L
S
S
S
S
Y
E
L
S
Site 37
S233
Q
R
E
S
G
L
S
S
S
S
Y
E
L
S
Q
Site 38
S234
R
E
S
G
L
S
S
S
S
Y
E
L
S
Q
Y
Site 39
S235
E
S
G
L
S
S
S
S
Y
E
L
S
Q
Y
I
Site 40
Y236
S
G
L
S
S
S
S
Y
E
L
S
Q
Y
I
R
Site 41
S239
S
S
S
S
Y
E
L
S
Q
Y
I
R
D
A
P
Site 42
Y241
S
S
Y
E
L
S
Q
Y
I
R
D
A
P
E
R
Site 43
S254
E
R
D
D
P
P
A
S
A
A
W
S
P
V
Q
Site 44
S258
P
P
A
S
A
A
W
S
P
V
Q
A
D
V
S
Site 45
S266
P
V
Q
A
D
V
S
S
A
G
P
K
A
P
M
Site 46
Y276
P
K
A
P
M
K
F
Y
I
P
H
V
P
V
S
Site 47
S297
L
V
H
V
G
P
S
S
P
T
D
G
Q
A
A
Site 48
S318
M
E
V
I
L
N
D
S
E
E
Q
E
E
M
R
Site 49
S326
E
E
Q
E
E
M
R
S
F
S
G
P
L
I
R
Site 50
S328
Q
E
E
M
R
S
F
S
G
P
L
I
R
E
D
Site 51
S355
K
A
A
Q
S
C
K
S
E
T
L
G
S
R
D
Site 52
S360
C
K
S
E
T
L
G
S
R
D
S
A
L
L
W
Site 53
Y399
D
C
K
K
L
E
K
Y
K
R
Q
P
P
V
A
Site 54
S421
E
D
W
P
V
L
S
S
G
T
P
N
L
L
T
Site 55
T423
W
P
V
L
S
S
G
T
P
N
L
L
T
G
E
Site 56
T428
S
G
T
P
N
L
L
T
G
E
I
P
P
S
V
Site 57
S434
L
T
G
E
I
P
P
S
V
E
T
P
A
Q
I
Site 58
T437
E
I
P
P
S
V
E
T
P
A
Q
I
V
E
K
Site 59
Y450
E
K
F
T
R
L
L
Y
Y
G
R
K
K
E
A
Site 60
Y451
K
F
T
R
L
L
Y
Y
G
R
K
K
E
A
L
Site 61
S474
W
G
H
A
L
F
L
S
S
K
M
D
P
Q
T
Site 62
T481
S
S
K
M
D
P
Q
T
Y
S
W
V
M
S
G
Site 63
Y482
S
K
M
D
P
Q
T
Y
S
W
V
M
S
G
F
Site 64
S534
P
H
L
A
V
I
L
S
N
Q
A
G
D
P
E
Site 65
Y577
A
H
V
P
F
G
H
Y
T
V
K
T
D
H
L
Site 66
S589
D
H
L
V
L
L
G
S
S
H
S
Q
E
F
L
Site 67
Y612
Q
R
T
E
I
F
E
Y
C
Q
M
L
G
R
P
Site 68
S621
Q
M
L
G
R
P
K
S
F
I
P
S
F
Q
V
Site 69
S625
R
P
K
S
F
I
P
S
F
Q
V
Y
K
L
L
Site 70
S659
A
I
G
A
A
V
L
S
Q
G
E
S
S
H
P
Site 71
S682
L
A
E
K
L
K
L
S
D
P
L
V
L
E
R
Site 72
S691
P
L
V
L
E
R
R
S
G
D
R
D
L
E
P
Site 73
S724
G
D
P
H
P
T
R
S
D
I
S
G
A
G
G
Site 74
S727
H
P
T
R
S
D
I
S
G
A
G
G
T
T
T
Site 75
T734
S
G
A
G
G
T
T
T
E
N
T
F
Y
Q
D
Site 76
T737
G
G
T
T
T
E
N
T
F
Y
Q
D
F
S
G
Site 77
Y739
T
T
T
E
N
T
F
Y
Q
D
F
S
G
C
Q
Site 78
S749
F
S
G
C
Q
G
Y
S
E
A
P
G
Y
R
S
Site 79
Y754
G
Y
S
E
A
P
G
Y
R
S
A
L
W
L
T
Site 80
S771
Q
T
C
L
L
Q
P
S
P
Q
Q
P
F
P
L
Site 81
S782
P
F
P
L
Q
P
G
S
Y
P
A
G
G
G
A
Site 82
Y783
F
P
L
Q
P
G
S
Y
P
A
G
G
G
A
G
Site 83
T792
A
G
G
G
A
G
Q
T
G
T
P
R
P
F
Y
Site 84
T794
G
G
A
G
Q
T
G
T
P
R
P
F
Y
S
V
Site 85
Y799
T
G
T
P
R
P
F
Y
S
V
P
E
T
H
L
Site 86
S800
G
T
P
R
P
F
Y
S
V
P
E
T
H
L
P
Site 87
T804
P
F
Y
S
V
P
E
T
H
L
P
G
T
G
S
Site 88
T830
V
W
E
E
M
L
Q
T
H
L
G
P
G
E
N
Site 89
T838
H
L
G
P
G
E
N
T
V
S
Q
E
T
S
Q
Site 90
S840
G
P
G
E
N
T
V
S
Q
E
T
S
Q
P
P
Site 91
S844
N
T
V
S
Q
E
T
S
Q
P
P
D
G
Q
E
Site 92
S854
P
D
G
Q
E
V
I
S
K
P
Q
T
P
L
A
Site 93
T858
E
V
I
S
K
P
Q
T
P
L
A
A
R
P
R
Site 94
S866
P
L
A
A
R
P
R
S
I
S
E
S
S
A
S
Site 95
S868
A
A
R
P
R
S
I
S
E
S
S
A
S
S
A
Site 96
S870
R
P
R
S
I
S
E
S
S
A
S
S
A
K
E
Site 97
S871
P
R
S
I
S
E
S
S
A
S
S
A
K
E
D
Site 98
S873
S
I
S
E
S
S
A
S
S
A
K
E
D
E
K
Site 99
S874
I
S
E
S
S
A
S
S
A
K
E
D
E
K
E
Site 100
S882
A
K
E
D
E
K
E
S
S
D
E
A
D
K
N
Site 101
S883
K
E
D
E
K
E
S
S
D
E
A
D
K
N
S
Site 102
S890
S
D
E
A
D
K
N
S
P
R
N
T
A
Q
R
Site 103
T894
D
K
N
S
P
R
N
T
A
Q
R
G
K
L
G
Site 104
T907
L
G
D
G
K
E
H
T
K
S
S
G
F
G
W
Site 105
S909
D
G
K
E
H
T
K
S
S
G
F
G
W
F
S
Site 106
S916
S
S
G
F
G
W
F
S
W
F
R
S
K
P
T
Site 107
T923
S
W
F
R
S
K
P
T
K
N
A
S
P
A
G
Site 108
S927
S
K
P
T
K
N
A
S
P
A
G
D
E
D
S
Site 109
S934
S
P
A
G
D
E
D
S
S
D
S
P
D
S
E
Site 110
S935
P
A
G
D
E
D
S
S
D
S
P
D
S
E
E
Site 111
S937
G
D
E
D
S
S
D
S
P
D
S
E
E
T
P
Site 112
S940
D
S
S
D
S
P
D
S
E
E
T
P
R
A
S
Site 113
T943
D
S
P
D
S
E
E
T
P
R
A
S
S
P
H
Site 114
S947
S
E
E
T
P
R
A
S
S
P
H
Q
A
G
L
Site 115
S948
E
E
T
P
R
A
S
S
P
H
Q
A
G
L
G
Site 116
S957
H
Q
A
G
L
G
L
S
L
T
P
S
P
E
S
Site 117
T959
A
G
L
G
L
S
L
T
P
S
P
E
S
P
P
Site 118
S961
L
G
L
S
L
T
P
S
P
E
S
P
P
L
P
Site 119
S964
S
L
T
P
S
P
E
S
P
P
L
P
D
V
S
Site 120
S971
S
P
P
L
P
D
V
S
A
F
S
R
G
R
G
Site 121
S974
L
P
D
V
S
A
F
S
R
G
R
G
G
G
E
Site 122
S985
G
G
G
E
G
R
G
S
A
S
S
G
G
A
A
Site 123
S988
E
G
R
G
S
A
S
S
G
G
A
A
A
G
A
Site 124
S1007
L
S
G
P
E
S
V
S
F
E
L
C
S
N
P
Site 125
Y1030
L
K
G
A
V
P
L
Y
N
P
S
Q
V
P
Q
Site 126
S1033
A
V
P
L
Y
N
P
S
Q
V
P
Q
L
P
T
Site 127
S1043
P
Q
L
P
T
A
T
S
L
N
R
P
N
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation