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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF594
Full Name:
Zinc finger protein 594
Alias:
Zinc finger protein HZF18
Type:
Mass (Da):
93907
Number AA:
807
UniProt ID:
Q96JF6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
W
K
S
K
M
E
I
S
E
E
K
K
S
A
R
Site 2
S16
E
I
S
E
E
K
K
S
A
R
A
A
S
E
K
Site 3
S21
K
K
S
A
R
A
A
S
E
K
L
Q
R
Q
I
Site 4
T29
E
K
L
Q
R
Q
I
T
Q
E
C
E
L
V
E
Site 5
T37
Q
E
C
E
L
V
E
T
S
N
S
E
D
R
L
Site 6
S40
E
L
V
E
T
S
N
S
E
D
R
L
L
K
H
Site 7
S50
R
L
L
K
H
W
V
S
P
L
K
D
A
M
R
Site 8
S61
D
A
M
R
H
L
P
S
Q
E
S
G
I
R
E
Site 9
S64
R
H
L
P
S
Q
E
S
G
I
R
E
M
H
I
Site 10
S93
N
E
G
E
K
I
L
S
A
G
E
S
S
H
R
Site 11
S97
K
I
L
S
A
G
E
S
S
H
R
Y
E
V
S
Site 12
S98
I
L
S
A
G
E
S
S
H
R
Y
E
V
S
G
Site 13
Y101
A
G
E
S
S
H
R
Y
E
V
S
G
Q
N
F
Site 14
S104
S
S
H
R
Y
E
V
S
G
Q
N
F
K
Q
K
Site 15
S112
G
Q
N
F
K
Q
K
S
G
L
T
E
H
Q
K
Site 16
Y127
I
H
N
I
N
K
T
Y
E
C
K
E
C
E
K
Site 17
T135
E
C
K
E
C
E
K
T
F
N
R
S
S
N
L
Site 18
S140
E
K
T
F
N
R
S
S
N
L
I
I
H
Q
R
Site 19
T150
I
I
H
Q
R
I
H
T
G
N
K
P
Y
V
C
Site 20
Y155
I
H
T
G
N
K
P
Y
V
C
N
E
C
G
K
Site 21
S164
C
N
E
C
G
K
D
S
N
Q
S
S
N
L
I
Site 22
S168
G
K
D
S
N
Q
S
S
N
L
I
I
H
Q
R
Site 23
T178
I
I
H
Q
R
I
H
T
G
K
K
P
Y
I
C
Site 24
Y183
I
H
T
G
K
K
P
Y
I
C
H
E
C
G
K
Site 25
S196
G
K
D
F
N
Q
S
S
N
L
V
R
H
K
Q
Site 26
Y211
I
H
S
G
G
N
P
Y
E
C
K
E
C
G
K
Site 27
S224
G
K
A
F
K
G
S
S
N
L
V
L
H
Q
R
Site 28
S234
V
L
H
Q
R
I
H
S
R
G
K
P
Y
L
C
Site 29
Y239
I
H
S
R
G
K
P
Y
L
C
N
K
C
G
K
Site 30
S249
N
K
C
G
K
A
F
S
Q
S
T
D
L
I
I
Site 31
T262
I
I
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 32
Y267
I
H
T
G
E
K
P
Y
E
C
Y
D
C
G
Q
Site 33
Y270
G
E
K
P
Y
E
C
Y
D
C
G
Q
M
F
S
Site 34
S277
Y
D
C
G
Q
M
F
S
Q
S
S
H
L
V
P
Site 35
T290
V
P
H
Q
R
I
H
T
G
E
K
P
L
K
C
Site 36
S308
E
K
A
F
R
Q
H
S
H
L
T
E
H
Q
R
Site 37
T311
F
R
Q
H
S
H
L
T
E
H
Q
R
L
H
S
Site 38
S318
T
E
H
Q
R
L
H
S
G
E
K
P
Y
E
C
Site 39
Y323
L
H
S
G
E
K
P
Y
E
C
H
R
C
G
K
Site 40
T331
E
C
H
R
C
G
K
T
F
S
G
R
T
A
F
Site 41
S333
H
R
C
G
K
T
F
S
G
R
T
A
F
L
K
Site 42
T356
K
I
E
E
C
E
K
T
F
S
K
D
E
E
L
Site 43
S358
E
E
C
E
K
T
F
S
K
D
E
E
L
R
E
Site 44
T388
C
G
R
N
F
Q
G
T
S
D
L
I
R
H
Q
Site 45
Y404
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 46
T412
E
C
K
E
C
G
K
T
F
N
Q
S
S
D
L
Site 47
S416
C
G
K
T
F
N
Q
S
S
D
L
L
R
H
H
Site 48
S417
G
K
T
F
N
Q
S
S
D
L
L
R
H
H
R
Site 49
S440
V
C
S
K
C
G
K
S
F
R
G
S
S
D
L
Site 50
S444
C
G
K
S
F
R
G
S
S
D
L
I
R
H
H
Site 51
S445
G
K
S
F
R
G
S
S
D
L
I
R
H
H
R
Site 52
T455
I
R
H
H
R
V
H
T
G
E
K
P
Y
E
C
Site 53
Y460
V
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 54
S463
G
E
K
P
Y
E
C
S
E
C
G
K
A
F
S
Site 55
S470
S
E
C
G
K
A
F
S
Q
R
S
H
L
V
T
Site 56
S473
G
K
A
F
S
Q
R
S
H
L
V
T
H
Q
K
Site 57
T477
S
Q
R
S
H
L
V
T
H
Q
K
I
H
T
G
Site 58
T483
V
T
H
Q
K
I
H
T
G
E
K
P
Y
Q
C
Site 59
Y488
I
H
T
G
E
K
P
Y
Q
C
T
E
C
G
K
Site 60
S501
G
K
A
F
R
R
R
S
L
L
I
Q
H
R
R
Site 61
S511
I
Q
H
R
R
I
H
S
G
E
K
P
Y
E
C
Site 62
Y516
I
H
S
G
E
K
P
Y
E
C
K
E
C
G
K
Site 63
T548
E
K
L
E
C
E
K
T
F
S
Q
D
E
E
L
Site 64
S550
L
E
C
E
K
T
F
S
Q
D
E
E
L
R
G
Site 65
S580
C
G
R
A
F
Q
G
S
S
D
L
I
R
H
Q
Site 66
Y596
T
H
T
R
E
K
P
Y
E
C
K
E
C
G
K
Site 67
S619
L
R
H
H
R
I
H
S
G
E
K
P
Y
V
C
Site 68
Y624
I
H
S
G
E
K
P
Y
V
C
N
K
C
G
K
Site 69
S632
V
C
N
K
C
G
K
S
F
R
G
S
S
D
L
Site 70
S636
C
G
K
S
F
R
G
S
S
D
L
I
K
H
H
Site 71
S637
G
K
S
F
R
G
S
S
D
L
I
K
H
H
R
Site 72
T647
I
K
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 73
Y652
I
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 74
S662
S
E
C
G
K
A
F
S
Q
R
S
H
L
A
T
Site 75
T669
S
Q
R
S
H
L
A
T
H
Q
K
I
H
T
G
Site 76
T675
A
T
H
Q
K
I
H
T
G
E
K
P
Y
Q
C
Site 77
Y680
I
H
T
G
E
K
P
Y
Q
C
S
E
C
G
N
Site 78
S693
G
N
A
F
R
R
R
S
L
L
I
Q
H
R
R
Site 79
S703
I
Q
H
R
R
L
H
S
G
E
K
P
Y
E
C
Site 80
Y708
L
H
S
G
E
K
P
Y
E
C
K
E
C
G
K
Site 81
T741
K
L
E
E
C
E
K
T
F
S
K
D
E
E
L
Site 82
S743
E
E
C
E
K
T
F
S
K
D
E
E
L
R
K
Site 83
T754
E
L
R
K
E
Q
R
T
H
Q
E
K
K
V
Y
Site 84
S773
C
S
R
T
F
Q
G
S
S
D
L
I
R
H
Q
Site 85
T797
E
C
K
E
C
G
K
T
Q
S
E
L
R
P
S
Site 86
S799
K
E
C
G
K
T
Q
S
E
L
R
P
S
E
T
Site 87
S804
T
Q
S
E
L
R
P
S
E
T
S
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation