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Updated November 2019
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Protein Info
Short Name:
ZNF469
Full Name:
Zinc finger protein 469
Alias:
KIAA1858; Zinc finger 469; ZN469
Type:
Unknown function
Mass (Da):
410202
Number AA:
2469
UniProt ID:
Q96JG9
International Prot ID:
IPI00084684
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
P
R
G
A
P
P
P
T
M
T
G
D
L
Q
P
Site 2
S25
L
Q
P
R
Q
V
A
S
S
P
G
H
P
S
Q
Site 3
S26
Q
P
R
Q
V
A
S
S
P
G
H
P
S
Q
P
Site 4
S31
A
S
S
P
G
H
P
S
Q
P
P
L
E
D
N
Site 5
T39
Q
P
P
L
E
D
N
T
P
A
T
R
T
T
K
Site 6
T45
N
T
P
A
T
R
T
T
K
G
A
R
E
A
G
Site 7
S77
D
G
E
L
K
P
P
S
L
R
G
Q
A
P
S
Site 8
S84
S
L
R
G
Q
A
P
S
S
T
P
G
K
R
G
Site 9
S85
L
R
G
Q
A
P
S
S
T
P
G
K
R
G
S
Site 10
T86
R
G
Q
A
P
S
S
T
P
G
K
R
G
S
P
Site 11
S92
S
T
P
G
K
R
G
S
P
Q
T
P
P
G
R
Site 12
T95
G
K
R
G
S
P
Q
T
P
P
G
R
S
P
L
Site 13
S100
P
Q
T
P
P
G
R
S
P
L
Q
A
P
S
R
Site 14
S115
L
A
G
R
A
E
G
S
P
P
Q
R
Y
I
L
Site 15
Y120
E
G
S
P
P
Q
R
Y
I
L
G
I
A
S
S
Site 16
S126
R
Y
I
L
G
I
A
S
S
R
T
K
P
T
L
Site 17
S127
Y
I
L
G
I
A
S
S
R
T
K
P
T
L
D
Site 18
T132
A
S
S
R
T
K
P
T
L
D
E
T
P
E
N
Site 19
T136
T
K
P
T
L
D
E
T
P
E
N
P
Q
L
E
Site 20
T152
A
Q
L
P
E
V
D
T
P
Q
G
P
G
T
G
Site 21
T158
D
T
P
Q
G
P
G
T
G
A
P
L
R
P
G
Site 22
S189
R
C
F
Q
E
P
P
S
S
F
T
S
T
N
Y
Site 23
S190
C
F
Q
E
P
P
S
S
F
T
S
T
N
Y
T
Site 24
S193
E
P
P
S
S
F
T
S
T
N
Y
T
S
P
S
Site 25
T194
P
P
S
S
F
T
S
T
N
Y
T
S
P
S
A
Site 26
Y196
S
S
F
T
S
T
N
Y
T
S
P
S
A
T
P
Site 27
T197
S
F
T
S
T
N
Y
T
S
P
S
A
T
P
R
Site 28
S198
F
T
S
T
N
Y
T
S
P
S
A
T
P
R
P
Site 29
S200
S
T
N
Y
T
S
P
S
A
T
P
R
P
P
A
Site 30
T202
N
Y
T
S
P
S
A
T
P
R
P
P
A
P
G
Site 31
S213
P
A
P
G
P
P
Q
S
R
G
T
S
P
L
Q
Site 32
T216
G
P
P
Q
S
R
G
T
S
P
L
Q
P
G
S
Site 33
S217
P
P
Q
S
R
G
T
S
P
L
Q
P
G
S
Y
Site 34
S223
T
S
P
L
Q
P
G
S
Y
P
E
Y
Q
A
S
Site 35
Y224
S
P
L
Q
P
G
S
Y
P
E
Y
Q
A
S
G
Site 36
Y227
Q
P
G
S
Y
P
E
Y
Q
A
S
G
A
D
S
Site 37
S230
S
Y
P
E
Y
Q
A
S
G
A
D
S
W
P
P
Site 38
S234
Y
Q
A
S
G
A
D
S
W
P
P
A
A
E
N
Site 39
S242
W
P
P
A
A
E
N
S
F
P
G
A
N
F
G
Site 40
S262
P
E
P
I
P
K
G
S
R
P
G
G
S
P
R
Site 41
S267
K
G
S
R
P
G
G
S
P
R
G
V
S
F
Q
Site 42
S272
G
G
S
P
R
G
V
S
F
Q
F
P
F
P
A
Site 43
S284
F
P
A
L
H
G
A
S
T
K
P
F
P
A
D
Site 44
T320
W
P
E
E
A
V
G
T
G
P
A
Y
P
L
P
Site 45
Y324
A
V
G
T
G
P
A
Y
P
L
P
T
Q
P
A
Site 46
S333
L
P
T
Q
P
A
P
S
P
L
P
C
Y
Q
G
Site 47
Y338
A
P
S
P
L
P
C
Y
Q
G
Q
P
G
G
L
Site 48
S349
P
G
G
L
N
R
H
S
D
L
S
G
A
L
S
Site 49
S352
L
N
R
H
S
D
L
S
G
A
L
S
S
P
G
Site 50
S356
S
D
L
S
G
A
L
S
S
P
G
A
A
H
S
Site 51
S357
D
L
S
G
A
L
S
S
P
G
A
A
H
S
A
Site 52
S363
S
S
P
G
A
A
H
S
A
P
R
P
F
S
D
Site 53
S369
H
S
A
P
R
P
F
S
D
S
L
H
K
S
L
Site 54
S371
A
P
R
P
F
S
D
S
L
H
K
S
L
T
K
Site 55
S375
F
S
D
S
L
H
K
S
L
T
K
I
L
P
E
Site 56
S386
I
L
P
E
R
P
P
S
A
Q
D
G
L
G
S
Site 57
S393
S
A
Q
D
G
L
G
S
T
R
G
P
P
S
S
Site 58
T394
A
Q
D
G
L
G
S
T
R
G
P
P
S
S
L
Site 59
S399
G
S
T
R
G
P
P
S
S
L
P
Q
R
H
F
Site 60
S400
S
T
R
G
P
P
S
S
L
P
Q
R
H
F
P
Site 61
S414
P
G
Q
A
Y
R
A
S
G
V
D
T
S
P
G
Site 62
T418
Y
R
A
S
G
V
D
T
S
P
G
P
P
D
T
Site 63
S419
R
A
S
G
V
D
T
S
P
G
P
P
D
T
E
Site 64
T425
T
S
P
G
P
P
D
T
E
L
A
A
P
G
P
Site 65
T444
L
P
Q
L
W
D
P
T
A
A
P
Y
P
T
P
Site 66
Y448
W
D
P
T
A
A
P
Y
P
T
P
P
G
G
P
Site 67
T450
P
T
A
A
P
Y
P
T
P
P
G
G
P
L
A
Site 68
T459
P
G
G
P
L
A
A
T
R
S
M
F
F
N
G
Site 69
S461
G
P
L
A
A
T
R
S
M
F
F
N
G
Q
P
Site 70
S469
M
F
F
N
G
Q
P
S
P
G
Q
R
L
C
L
Site 71
S479
Q
R
L
C
L
P
Q
S
A
P
L
P
W
P
Q
Site 72
T490
P
W
P
Q
V
L
P
T
A
R
P
S
P
H
G
Site 73
S494
V
L
P
T
A
R
P
S
P
H
G
M
E
M
L
Site 74
S502
P
H
G
M
E
M
L
S
R
L
P
F
P
A
G
Site 75
T527
A
L
G
T
A
G
K
T
P
G
P
R
E
K
L
Site 76
S539
E
K
L
P
A
V
R
S
S
Q
G
G
S
P
A
Site 77
S540
K
L
P
A
V
R
S
S
Q
G
G
S
P
A
L
Site 78
S544
V
R
S
S
Q
G
G
S
P
A
L
F
T
Y
N
Site 79
T549
G
G
S
P
A
L
F
T
Y
N
G
M
T
D
P
Site 80
Y550
G
S
P
A
L
F
T
Y
N
G
M
T
D
P
G
Site 81
S571
G
V
A
Q
P
Q
V
S
P
H
G
T
P
S
L
Site 82
T575
P
Q
V
S
P
H
G
T
P
S
L
P
P
P
R
Site 83
S577
V
S
P
H
G
T
P
S
L
P
P
P
R
V
V
Site 84
S587
P
P
R
V
V
G
A
S
P
S
E
S
P
L
P
Site 85
S589
R
V
V
G
A
S
P
S
E
S
P
L
P
S
P
Site 86
S591
V
G
A
S
P
S
E
S
P
L
P
S
P
A
T
Site 87
S595
P
S
E
S
P
L
P
S
P
A
T
N
T
A
G
Site 88
T598
S
P
L
P
S
P
A
T
N
T
A
G
S
T
C
Site 89
S603
P
A
T
N
T
A
G
S
T
C
S
S
L
S
P
Site 90
T604
A
T
N
T
A
G
S
T
C
S
S
L
S
P
M
Site 91
S607
T
A
G
S
T
C
S
S
L
S
P
M
S
S
S
Site 92
S609
G
S
T
C
S
S
L
S
P
M
S
S
S
P
A
Site 93
S612
C
S
S
L
S
P
M
S
S
S
P
A
N
P
S
Site 94
S613
S
S
L
S
P
M
S
S
S
P
A
N
P
S
S
Site 95
S614
S
L
S
P
M
S
S
S
P
A
N
P
S
S
E
Site 96
S619
S
S
S
P
A
N
P
S
S
E
E
S
Q
L
P
Site 97
S620
S
S
P
A
N
P
S
S
E
E
S
Q
L
P
G
Site 98
S623
A
N
P
S
S
E
E
S
Q
L
P
G
P
L
G
Site 99
T639
S
A
F
F
H
P
P
T
H
P
Q
E
T
G
S
Site 100
T644
P
P
T
H
P
Q
E
T
G
S
P
F
P
S
P
Site 101
S646
T
H
P
Q
E
T
G
S
P
F
P
S
P
E
P
Site 102
S650
E
T
G
S
P
F
P
S
P
E
P
P
H
S
L
Site 103
S656
P
S
P
E
P
P
H
S
L
P
T
H
Y
Q
P
Site 104
T688
A
F
Q
C
L
E
E
T
P
F
P
H
E
G
P
Site 105
Y712
F
P
R
A
P
P
P
Y
P
T
H
H
F
S
L
Site 106
T714
R
A
P
P
P
Y
P
T
H
H
F
S
L
S
S
Site 107
S718
P
Y
P
T
H
H
F
S
L
S
S
A
S
L
D
Site 108
S720
P
T
H
H
F
S
L
S
S
A
S
L
D
Q
L
Site 109
T732
D
Q
L
D
V
L
L
T
C
R
Q
C
D
R
N
Site 110
Y740
C
R
Q
C
D
R
N
Y
S
S
L
A
A
F
L
Site 111
S741
R
Q
C
D
R
N
Y
S
S
L
A
A
F
L
A
Site 112
S742
Q
C
D
R
N
Y
S
S
L
A
A
F
L
A
H
Site 113
S767
A
K
D
G
H
Q
R
S
P
G
P
P
G
L
P
Site 114
S775
P
G
P
P
G
L
P
S
P
P
A
A
P
R
V
Site 115
S830
T
P
F
P
L
P
A
S
D
L
D
M
E
D
D
Site 116
S842
E
D
D
A
K
L
D
S
L
I
T
E
A
L
N
Site 117
Y853
E
A
L
N
G
M
E
Y
Q
S
D
N
P
E
I
Site 118
S855
L
N
G
M
E
Y
Q
S
D
N
P
E
I
D
S
Site 119
S863
D
N
P
E
I
D
S
S
F
I
D
V
F
A
D
Site 120
S874
V
F
A
D
E
E
P
S
G
P
R
G
P
S
S
Site 121
S880
P
S
G
P
R
G
P
S
S
G
H
P
L
K
S
Site 122
S881
S
G
P
R
G
P
S
S
G
H
P
L
K
S
K
Site 123
S887
S
S
G
H
P
L
K
S
K
A
G
V
T
P
E
Site 124
T892
L
K
S
K
A
G
V
T
P
E
S
K
A
P
P
Site 125
S895
K
A
G
V
T
P
E
S
K
A
P
P
P
L
P
Site 126
T905
P
P
P
L
P
A
A
T
P
D
P
Q
T
P
R
Site 127
T910
A
A
T
P
D
P
Q
T
P
R
P
G
D
R
G
Site 128
T926
P
A
R
G
R
P
K
T
R
S
L
G
L
A
P
Site 129
S928
R
G
R
P
K
T
R
S
L
G
L
A
P
T
E
Site 130
T934
R
S
L
G
L
A
P
T
E
A
D
A
P
S
Q
Site 131
S940
P
T
E
A
D
A
P
S
Q
G
R
Q
Q
R
R
Site 132
S960
L
F
R
K
D
L
D
S
G
G
A
A
E
G
S
Site 133
S967
S
G
G
A
A
E
G
S
G
S
G
G
G
G
R
Site 134
S969
G
A
A
E
G
S
G
S
G
G
G
G
R
A
S
Site 135
S976
S
G
G
G
G
R
A
S
G
L
R
P
R
R
N
Site 136
T999
P
R
P
R
R
P
R
T
Q
A
P
G
S
R
A
Site 137
S1004
P
R
T
Q
A
P
G
S
R
A
D
P
A
P
R
Site 138
S1024
A
L
P
E
E
T
R
S
S
R
R
R
R
L
P
Site 139
S1025
L
P
E
E
T
R
S
S
R
R
R
R
L
P
P
Site 140
Y1064
Q
K
N
R
L
R
E
Y
D
F
A
S
E
S
E
Site 141
S1068
L
R
E
Y
D
F
A
S
E
S
E
E
D
E
Q
Site 142
S1070
E
Y
D
F
A
S
E
S
E
E
D
E
Q
P
P
Site 143
T1099
K
R
K
E
V
E
L
T
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G
T
K
T
Site 447
T3714
S
G
S
P
R
P
G
T
K
T
G
G
G
S
Q
Site 448
T3716
S
P
R
P
G
T
K
T
G
G
G
S
Q
P
Q
Site 449
S3720
G
T
K
T
G
G
G
S
Q
P
Q
P
A
S
G
Site 450
S3726
G
S
Q
P
Q
P
A
S
G
Q
L
Q
S
E
T
Site 451
S3731
P
A
S
G
Q
L
Q
S
E
T
A
T
T
P
A
Site 452
T3735
Q
L
Q
S
E
T
A
T
T
P
A
K
P
S
F
Site 453
T3736
L
Q
S
E
T
A
T
T
P
A
K
P
S
F
P
Site 454
S3741
A
T
T
P
A
K
P
S
F
P
S
R
S
P
A
Site 455
S3744
P
A
K
P
S
F
P
S
R
S
P
A
P
E
R
Site 456
S3746
K
P
S
F
P
S
R
S
P
A
P
E
R
L
P
Site 457
S3760
P
A
R
A
Q
A
K
S
C
T
K
G
P
R
E
Site 458
S3776
G
E
Q
G
P
H
G
S
L
G
P
K
E
K
G
Site 459
S3786
P
K
E
K
G
E
S
S
T
K
R
K
K
G
Q
Site 460
T3787
K
E
K
G
E
S
S
T
K
R
K
K
G
Q
V
Site 461
S3800
Q
V
P
G
P
A
R
S
E
S
V
G
S
F
G
Site 462
S3802
P
G
P
A
R
S
E
S
V
G
S
F
G
R
A
Site 463
S3805
A
R
S
E
S
V
G
S
F
G
R
A
P
S
A
Site 464
S3811
G
S
F
G
R
A
P
S
A
P
D
K
P
P
R
Site 465
T3819
A
P
D
K
P
P
R
T
P
R
K
Q
A
T
P
Site 466
T3825
R
T
P
R
K
Q
A
T
P
S
R
V
L
P
T
Site 467
S3838
P
T
K
P
K
P
N
S
Q
N
K
P
R
P
P
Site 468
S3847
N
K
P
R
P
P
P
S
E
Q
R
K
A
E
P
Site 469
T3857
R
K
A
E
P
G
H
T
Q
R
K
D
R
L
G
Site 470
T3881
L
R
P
P
K
R
G
T
A
V
H
G
A
E
P
Site 471
T3893
A
E
P
A
E
P
H
T
H
R
T
A
E
A
Q
Site 472
S3905
E
A
Q
S
D
L
L
S
Q
L
F
G
Q
R
L
Site 473
T3913
Q
L
F
G
Q
R
L
T
G
F
K
I
P
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation