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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1849
Full Name:
Ras-associating and dilute domain-containing protein
Alias:
FLJ10324; K1849; LOC55698; Ras association and DIL domains
Type:
Unknown function
Mass (Da):
117407
Number AA:
1075
UniProt ID:
Q96JH8
International Prot ID:
IPI00437989
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007275
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Y
G
T
H
F
I
M
S
P
P
T
K
S
K
L
Site 2
S15
I
M
S
P
P
T
K
S
K
L
K
R
Q
S
Q
Site 3
S21
K
S
K
L
K
R
Q
S
Q
L
L
S
S
M
L
Site 4
S25
K
R
Q
S
Q
L
L
S
S
M
L
S
R
T
L
Site 5
S26
R
Q
S
Q
L
L
S
S
M
L
S
R
T
L
S
Site 6
S29
Q
L
L
S
S
M
L
S
R
T
L
S
Y
K
Y
Site 7
T31
L
S
S
M
L
S
R
T
L
S
Y
K
Y
R
D
Site 8
S33
S
M
L
S
R
T
L
S
Y
K
Y
R
D
L
D
Site 9
Y36
S
R
T
L
S
Y
K
Y
R
D
L
D
S
T
F
Site 10
S41
Y
K
Y
R
D
L
D
S
T
F
S
S
L
G
A
Site 11
T42
K
Y
R
D
L
D
S
T
F
S
S
L
G
A
S
Site 12
S44
R
D
L
D
S
T
F
S
S
L
G
A
S
D
D
Site 13
S45
D
L
D
S
T
F
S
S
L
G
A
S
D
D
P
Site 14
S49
T
F
S
S
L
G
A
S
D
D
P
A
E
L
S
Site 15
S56
S
D
D
P
A
E
L
S
T
Q
L
S
A
P
G
Site 16
T76
G
D
S
V
C
T
G
T
H
Y
K
S
V
L
A
Site 17
Y78
S
V
C
T
G
T
H
Y
K
S
V
L
A
T
G
Site 18
S80
C
T
G
T
H
Y
K
S
V
L
A
T
G
T
S
Site 19
T84
H
Y
K
S
V
L
A
T
G
T
S
S
A
R
E
Site 20
S88
V
L
A
T
G
T
S
S
A
R
E
L
V
K
E
Site 21
Y110
D
P
R
Q
A
G
Q
Y
V
L
C
D
V
V
G
Site 22
S154
W
K
P
R
E
G
L
S
R
R
F
E
L
R
K
Site 23
S163
R
F
E
L
R
K
R
S
D
V
E
E
L
A
A
Site 24
S190
Q
A
R
R
L
Q
R
S
R
A
K
G
T
P
T
Site 25
T195
Q
R
S
R
A
K
G
T
P
T
P
A
L
G
D
Site 26
T197
S
R
A
K
G
T
P
T
P
A
L
G
D
A
R
Site 27
S205
P
A
L
G
D
A
R
S
S
P
P
P
R
L
R
Site 28
S206
A
L
G
D
A
R
S
S
P
P
P
R
L
R
R
Site 29
T214
P
P
P
R
L
R
R
T
V
S
E
T
S
L
S
Site 30
S216
P
R
L
R
R
T
V
S
E
T
S
L
S
P
V
Site 31
T218
L
R
R
T
V
S
E
T
S
L
S
P
V
N
A
Site 32
S219
R
R
T
V
S
E
T
S
L
S
P
V
N
A
L
Site 33
Y243
P
G
P
D
A
M
R
Y
S
L
Y
Q
S
P
H
Site 34
S244
G
P
D
A
M
R
Y
S
L
Y
Q
S
P
H
L
Site 35
Y246
D
A
M
R
Y
S
L
Y
Q
S
P
H
L
L
L
Site 36
S248
M
R
Y
S
L
Y
Q
S
P
H
L
L
L
L
Q
Site 37
S263
G
Y
S
Q
Q
H
D
S
L
V
Y
V
L
N
R
Site 38
Y266
Q
Q
H
D
S
L
V
Y
V
L
N
R
D
R
H
Site 39
T274
V
L
N
R
D
R
H
T
V
G
Q
R
T
P
S
Site 40
T279
R
H
T
V
G
Q
R
T
P
S
S
K
P
S
I
Site 41
S281
T
V
G
Q
R
T
P
S
S
K
P
S
I
S
L
Site 42
S282
V
G
Q
R
T
P
S
S
K
P
S
I
S
L
S
Site 43
S285
R
T
P
S
S
K
P
S
I
S
L
S
A
P
D
Site 44
S287
P
S
S
K
P
S
I
S
L
S
A
P
D
I
L
Site 45
T299
D
I
L
P
L
H
C
T
I
R
R
Q
P
L
P
Site 46
S308
R
R
Q
P
L
P
D
S
G
Q
A
A
G
R
L
Site 47
S330
A
H
I
S
V
N
F
S
E
V
G
H
R
T
V
Site 48
T336
F
S
E
V
G
H
R
T
V
V
L
H
H
G
D
Site 49
T395
A
R
G
A
A
S
P
T
Q
A
A
L
P
R
R
Site 50
T416
F
E
P
H
L
E
D
T
L
L
Q
R
I
M
T
Site 51
T470
I
A
R
L
I
R
E
T
V
W
E
K
T
K
E
Site 52
Y518
S
N
S
I
E
L
L
Y
F
I
Q
Q
K
C
P
Site 53
Y527
I
Q
Q
K
C
P
L
Y
M
Q
S
M
E
E
Q
Site 54
T538
M
E
E
Q
L
D
I
T
G
S
K
E
S
L
F
Site 55
S540
E
Q
L
D
I
T
G
S
K
E
S
L
F
S
C
Site 56
S543
D
I
T
G
S
K
E
S
L
F
S
C
T
L
T
Site 57
S546
G
S
K
E
S
L
F
S
C
T
L
T
A
S
E
Site 58
T548
K
E
S
L
F
S
C
T
L
T
A
S
E
E
A
Site 59
Y572
Y
A
F
Q
Q
C
V
Y
Y
V
S
K
S
L
Y
Site 60
T593
L
E
C
P
P
F
Q
T
E
R
R
E
S
W
S
Site 61
S598
F
Q
T
E
R
R
E
S
W
S
S
A
P
E
L
Site 62
S600
T
E
R
R
E
S
W
S
S
A
P
E
L
P
E
Site 63
S601
E
R
R
E
S
W
S
S
A
P
E
L
P
E
E
Site 64
S614
E
E
L
R
R
V
V
S
V
Y
Q
A
A
L
D
Site 65
S658
Q
L
L
D
R
G
P
S
L
S
C
F
H
W
P
Site 66
S660
L
D
R
G
P
S
L
S
C
F
H
W
P
R
G
Site 67
T736
A
Q
L
H
R
L
L
T
H
Y
Q
L
A
S
A
Site 68
S748
A
S
A
M
G
P
M
S
T
W
E
P
G
A
Q
Site 69
S757
W
E
P
G
A
Q
D
S
P
E
A
F
R
S
E
Site 70
S763
D
S
P
E
A
F
R
S
E
D
V
L
E
S
Y
Site 71
S769
R
S
E
D
V
L
E
S
Y
E
N
P
P
P
I
Site 72
Y770
S
E
D
V
L
E
S
Y
E
N
P
P
P
I
V
Site 73
Y797
N
C
L
D
D
S
I
Y
Q
H
L
L
Y
V
R
Site 74
S812
H
F
L
W
G
L
R
S
R
A
S
P
G
S
P
Site 75
S815
W
G
L
R
S
R
A
S
P
G
S
P
G
R
P
Site 76
S818
R
S
R
A
S
P
G
S
P
G
R
P
G
S
G
Site 77
S824
G
S
P
G
R
P
G
S
G
A
S
Q
P
V
C
Site 78
S827
G
R
P
G
S
G
A
S
Q
P
V
C
P
E
G
Site 79
S848
D
G
H
L
E
A
P
S
C
P
L
A
P
R
D
Site 80
S890
R
Q
P
G
R
G
G
S
Q
A
G
P
P
H
T
Site 81
T897
S
Q
A
G
P
P
H
T
D
S
S
C
L
L
T
Site 82
S899
A
G
P
P
H
T
D
S
S
C
L
L
T
P
P
Site 83
S900
G
P
P
H
T
D
S
S
C
L
L
T
P
P
S
Site 84
T904
T
D
S
S
C
L
L
T
P
P
S
T
P
L
G
Site 85
S907
S
C
L
L
T
P
P
S
T
P
L
G
P
E
P
Site 86
T908
C
L
L
T
P
P
S
T
P
L
G
P
E
P
G
Site 87
S922
G
D
P
D
W
P
E
S
G
G
P
C
G
K
A
Site 88
S957
S
A
A
L
A
E
E
S
P
P
A
P
S
S
R
Site 89
S962
E
E
S
P
P
A
P
S
S
R
S
S
S
T
E
Site 90
S963
E
S
P
P
A
P
S
S
R
S
S
S
T
E
D
Site 91
S965
P
P
A
P
S
S
R
S
S
S
T
E
D
F
C
Site 92
S966
P
A
P
S
S
R
S
S
S
T
E
D
F
C
Y
Site 93
S967
A
P
S
S
R
S
S
S
T
E
D
F
C
Y
V
Site 94
Y973
S
S
T
E
D
F
C
Y
V
F
T
V
E
L
E
Site 95
S1012
I
Q
T
L
L
P
G
S
P
A
A
A
D
G
R
Site 96
S1021
A
A
A
D
G
R
L
S
L
G
D
R
I
L
E
Site 97
S1060
M
R
F
L
V
A
K
S
D
V
E
T
A
K
K
Site 98
T1064
V
A
K
S
D
V
E
T
A
K
K
I
H
F
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation