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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ELMO2
Full Name:
Engulfment and cell motility protein 2
Alias:
CED12; CED-12; CED-12 homolog A; CED-12 homologue A; CED12A; ELM2; ELMO-2; Engulfment and cell motility 2; FLJ11656; HCED-12A; KIAA1834
Type:
Cytoskeletal protein
Mass (Da):
82615
Number AA:
720
UniProt ID:
Q96JJ3
International Prot ID:
IPI00260090
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0017124
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006897
GO:0006909
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y48
W
S
L
P
N
P
E
Y
Y
T
L
R
Y
A
D
Site 2
Y49
S
L
P
N
P
E
Y
Y
T
L
R
Y
A
D
G
Site 3
T50
L
P
N
P
E
Y
Y
T
L
R
Y
A
D
G
P
Site 4
Y60
Y
A
D
G
P
Q
L
Y
I
T
E
Q
T
R
S
Site 5
T62
D
G
P
Q
L
Y
I
T
E
Q
T
R
S
D
I
Site 6
S67
Y
I
T
E
Q
T
R
S
D
I
K
N
G
T
I
Site 7
S80
T
I
L
Q
L
A
I
S
P
S
R
A
A
R
Q
Site 8
S94
Q
L
M
E
R
T
Q
S
S
N
M
E
T
R
L
Site 9
T137
T
R
L
V
E
S
G
T
K
L
L
S
H
Y
S
Site 10
S141
E
S
G
T
K
L
L
S
H
Y
S
E
M
L
A
Site 11
S181
K
Q
I
A
G
Y
V
S
Q
P
M
V
D
V
S
Site 12
S204
L
E
S
M
V
L
N
S
Q
S
L
Y
Q
K
I
Site 13
S206
S
M
V
L
N
S
Q
S
L
Y
Q
K
I
A
E
Site 14
Y208
V
L
N
S
Q
S
L
Y
Q
K
I
A
E
E
I
Site 15
T216
Q
K
I
A
E
E
I
T
V
G
Q
L
I
S
H
Site 16
T280
R
G
N
R
P
I
K
T
E
M
A
H
Q
L
Y
Site 17
T303
L
L
E
E
R
M
M
T
K
M
D
P
N
D
Q
Site 18
S328
R
I
A
F
D
A
E
S
D
P
S
N
A
P
G
Site 19
S331
F
D
A
E
S
D
P
S
N
A
P
G
S
G
T
Site 20
S336
D
P
S
N
A
P
G
S
G
T
E
K
R
K
A
Site 21
T338
S
N
A
P
G
S
G
T
E
K
R
K
A
M
Y
Site 22
T346
E
K
R
K
A
M
Y
T
K
D
Y
K
M
L
G
Site 23
Y349
K
A
M
Y
T
K
D
Y
K
M
L
G
F
T
N
Site 24
T365
I
N
P
A
M
D
F
T
Q
T
P
P
G
M
L
Site 25
Y388
A
K
V
H
Q
D
T
Y
I
R
I
V
L
E
N
Site 26
S396
I
R
I
V
L
E
N
S
S
R
E
D
K
H
E
Site 27
Y434
P
N
E
G
R
N
D
Y
H
P
M
F
F
T
H
Site 28
T466
T
W
K
E
M
R
A
T
A
E
D
F
N
K
V
Site 29
S487
Q
I
T
R
A
L
P
S
K
P
N
S
L
D
Q
Site 30
S491
A
L
P
S
K
P
N
S
L
D
Q
F
K
S
K
Site 31
S497
N
S
L
D
Q
F
K
S
K
L
R
S
L
S
Y
Site 32
S501
Q
F
K
S
K
L
R
S
L
S
Y
S
E
I
L
Site 33
S503
K
S
K
L
R
S
L
S
Y
S
E
I
L
R
L
Site 34
Y504
S
K
L
R
S
L
S
Y
S
E
I
L
R
L
R
Site 35
S505
K
L
R
S
L
S
Y
S
E
I
L
R
L
R
Q
Site 36
S513
E
I
L
R
L
R
Q
S
E
R
M
S
Q
D
D
Site 37
S517
L
R
Q
S
E
R
M
S
Q
D
D
F
Q
S
P
Site 38
S523
M
S
Q
D
D
F
Q
S
P
P
I
V
E
L
R
Site 39
S553
L
N
R
L
C
E
G
S
S
F
R
K
I
G
N
Site 40
S554
N
R
L
C
E
G
S
S
F
R
K
I
G
N
R
Site 41
Y569
R
R
Q
E
R
F
W
Y
C
R
L
A
L
N
H
Site 42
T593
D
N
P
Q
G
E
V
T
F
E
S
L
Q
E
K
Site 43
S596
Q
G
E
V
T
F
E
S
L
Q
E
K
I
P
V
Site 44
T611
A
D
I
K
A
I
V
T
G
K
D
C
P
H
M
Site 45
Y639
E
L
A
F
S
I
L
Y
D
P
D
E
T
L
N
Site 46
T644
I
L
Y
D
P
D
E
T
L
N
F
I
A
P
N
Site 47
S671
A
L
L
G
K
D
M
S
S
E
L
T
K
S
D
Site 48
S672
L
L
G
K
D
M
S
S
E
L
T
K
S
D
L
Site 49
T675
K
D
M
S
S
E
L
T
K
S
D
L
D
T
L
Site 50
S677
M
S
S
E
L
T
K
S
D
L
D
T
L
L
S
Site 51
T681
L
T
K
S
D
L
D
T
L
L
S
M
E
M
K
Site 52
S684
S
D
L
D
T
L
L
S
M
E
M
K
L
R
L
Site 53
S711
P
P
I
P
K
E
P
S
S
Y
D
F
V
Y
H
Site 54
S712
P
I
P
K
E
P
S
S
Y
D
F
V
Y
H
Y
Site 55
Y713
I
P
K
E
P
S
S
Y
D
F
V
Y
H
Y
G
Site 56
Y717
P
S
S
Y
D
F
V
Y
H
Y
G
_
_
_
_
Site 57
Y719
S
Y
D
F
V
Y
H
Y
G
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation