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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
L3MBTL3
Full Name:
Lethal(3)malignant brain tumor-like protein 3
Alias:
H-l(3)mbt-like; KIAA1798; L (3)mbt-like 3; L(3)mbt-like 3; Lethal(3)malignant brain tumor-like 3; LMBL3; MBT1; MBT-1
Type:
Mass (Da):
88337
Number AA:
780
UniProt ID:
Q96JM7
International Prot ID:
IPI00306511
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0010468
GO:0010556
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
D
W
K
D
G
V
G
T
L
P
G
S
D
L
K
Site 2
S31
G
V
G
T
L
P
G
S
D
L
K
F
R
V
N
Site 3
T74
P
T
A
Q
E
A
P
T
S
P
P
S
S
R
P
Site 4
S75
T
A
Q
E
A
P
T
S
P
P
S
S
R
P
V
Site 5
S78
E
A
P
T
S
P
P
S
S
R
P
V
F
P
P
Site 6
S79
A
P
T
S
P
P
S
S
R
P
V
F
P
P
A
Site 7
Y87
R
P
V
F
P
P
A
Y
W
T
S
P
P
G
C
Site 8
T89
V
F
P
P
A
Y
W
T
S
P
P
G
C
P
T
Site 9
S90
F
P
P
A
Y
W
T
S
P
P
G
C
P
T
V
Site 10
T96
T
S
P
P
G
C
P
T
V
F
S
E
K
T
G
Site 11
S99
P
G
C
P
T
V
F
S
E
K
T
G
M
P
F
Site 12
S134
G
N
V
D
E
C
L
S
G
G
N
Y
C
S
Q
Site 13
Y138
E
C
L
S
G
G
N
Y
C
S
Q
N
C
A
R
Site 14
S178
R
K
K
K
P
K
L
S
L
K
A
D
T
K
E
Site 15
S206
D
V
R
I
L
R
G
S
Q
R
A
R
R
K
R
Site 16
S217
R
R
K
R
R
G
D
S
A
V
L
K
Q
G
L
Site 17
Y237
K
A
W
C
W
A
S
Y
L
E
E
E
K
A
V
Site 18
S256
K
L
F
K
E
H
Q
S
F
P
Y
N
K
N
G
Site 19
Y259
K
E
H
Q
S
F
P
Y
N
K
N
G
F
K
V
Site 20
T325
P
V
G
W
C
E
K
T
G
H
K
L
H
P
P
Site 21
S357
K
A
Q
A
A
P
K
S
L
F
E
N
Q
N
I
Site 22
T365
L
F
E
N
Q
N
I
T
V
I
P
S
G
F
R
Site 23
Y414
N
W
D
E
S
Y
D
Y
W
C
E
A
S
S
P
Site 24
T435
W
C
K
E
H
R
R
T
L
I
T
P
P
G
Y
Site 25
T438
E
H
R
R
T
L
I
T
P
P
G
Y
P
N
V
Site 26
Y442
T
L
I
T
P
P
G
Y
P
N
V
K
H
F
S
Site 27
Y453
K
H
F
S
W
D
K
Y
L
E
E
T
N
S
L
Site 28
S459
K
Y
L
E
E
T
N
S
L
P
A
P
A
R
A
Site 29
T496
P
M
F
I
R
V
A
T
V
A
D
T
D
D
H
Site 30
S524
D
Y
W
I
D
A
D
S
P
D
I
H
P
V
G
Site 31
T536
P
V
G
W
C
S
K
T
G
H
P
L
Q
P
P
Site 32
S545
H
P
L
Q
P
P
L
S
P
L
E
L
M
E
A
Site 33
S553
P
L
E
L
M
E
A
S
E
H
G
G
C
S
T
Site 34
T560
S
E
H
G
G
C
S
T
P
G
C
K
G
I
G
Site 35
S579
A
R
H
L
G
P
H
S
A
A
N
C
P
Y
S
Site 36
S586
S
A
A
N
C
P
Y
S
E
I
N
L
N
K
D
Site 37
S601
R
I
F
P
D
R
L
S
G
E
M
P
P
A
S
Site 38
S608
S
G
E
M
P
P
A
S
P
S
F
P
R
N
K
Site 39
S610
E
M
P
P
A
S
P
S
F
P
R
N
K
R
T
Site 40
T617
S
F
P
R
N
K
R
T
D
A
N
E
S
S
S
Site 41
S622
K
R
T
D
A
N
E
S
S
S
S
P
E
I
R
Site 42
S624
T
D
A
N
E
S
S
S
S
P
E
I
R
D
Q
Site 43
S625
D
A
N
E
S
S
S
S
P
E
I
R
D
Q
H
Site 44
S646
D
F
E
E
R
T
E
S
E
M
R
T
S
H
E
Site 45
S651
T
E
S
E
M
R
T
S
H
E
A
R
G
A
R
Site 46
T662
R
G
A
R
E
E
P
T
V
Q
Q
A
Q
R
R
Site 47
S670
V
Q
Q
A
Q
R
R
S
A
V
F
L
S
F
K
Site 48
S678
A
V
F
L
S
F
K
S
P
I
P
C
L
P
L
Site 49
S691
P
L
R
W
E
Q
Q
S
K
L
L
P
T
V
A
Site 50
S703
T
V
A
G
I
P
A
S
K
V
S
K
W
S
T
Site 51
S709
A
S
K
V
S
K
W
S
T
D
E
V
S
E
F
Site 52
T710
S
K
V
S
K
W
S
T
D
E
V
S
E
F
I
Site 53
S714
K
W
S
T
D
E
V
S
E
F
I
Q
S
L
P
Site 54
S719
E
V
S
E
F
I
Q
S
L
P
G
C
E
E
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation