KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LCOR
Full Name:
Ligand-dependent corepressor
Alias:
FLJ38026; KIAA1795; Ligand dependent nuclear receptor corepressor; Mblk1-related protein 2; MLR2
Type:
Nuclear receptor co-regulator
Mass (Da):
47007
Number AA:
433
UniProt ID:
Q96JN0
International Prot ID:
IPI00478371
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0000122
GO:0006139
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
I
Q
Q
F
A
A
E
Y
T
S
K
N
S
S
T
Site 2
S14
Q
F
A
A
E
Y
T
S
K
N
S
S
T
Q
D
Site 3
S18
E
Y
T
S
K
N
S
S
T
Q
D
P
S
Q
P
Site 4
T19
Y
T
S
K
N
S
S
T
Q
D
P
S
Q
P
N
Site 5
S23
N
S
S
T
Q
D
P
S
Q
P
N
S
T
K
N
Site 6
S27
Q
D
P
S
Q
P
N
S
T
K
N
Q
S
L
P
Site 7
T28
D
P
S
Q
P
N
S
T
K
N
Q
S
L
P
K
Site 8
S32
P
N
S
T
K
N
Q
S
L
P
K
A
S
P
V
Site 9
S37
N
Q
S
L
P
K
A
S
P
V
T
T
S
P
T
Site 10
T40
L
P
K
A
S
P
V
T
T
S
P
T
A
A
T
Site 11
S42
K
A
S
P
V
T
T
S
P
T
A
A
T
T
Q
Site 12
T48
T
S
P
T
A
A
T
T
Q
N
P
V
L
S
K
Site 13
S63
L
L
M
A
D
Q
D
S
P
L
D
L
T
V
R
Site 14
T68
Q
D
S
P
L
D
L
T
V
R
K
S
Q
S
E
Site 15
S72
L
D
L
T
V
R
K
S
Q
S
E
P
S
E
Q
Site 16
S74
L
T
V
R
K
S
Q
S
E
P
S
E
Q
D
G
Site 17
S77
R
K
S
Q
S
E
P
S
E
Q
D
G
V
L
D
Site 18
S86
Q
D
G
V
L
D
L
S
T
K
K
S
P
C
A
Site 19
T87
D
G
V
L
D
L
S
T
K
K
S
P
C
A
G
Site 20
S90
L
D
L
S
T
K
K
S
P
C
A
G
S
T
S
Site 21
S95
K
K
S
P
C
A
G
S
T
S
L
S
H
S
P
Site 22
S97
S
P
C
A
G
S
T
S
L
S
H
S
P
G
C
Site 23
S99
C
A
G
S
T
S
L
S
H
S
P
G
C
S
S
Site 24
S101
G
S
T
S
L
S
H
S
P
G
C
S
S
T
Q
Site 25
S105
L
S
H
S
P
G
C
S
S
T
Q
G
N
G
R
Site 26
S106
S
H
S
P
G
C
S
S
T
Q
G
N
G
R
P
Site 27
S117
N
G
R
P
G
R
P
S
Q
Y
R
P
D
G
L
Site 28
Y119
R
P
G
R
P
S
Q
Y
R
P
D
G
L
R
S
Site 29
S126
Y
R
P
D
G
L
R
S
G
D
G
V
P
P
R
Site 30
S134
G
D
G
V
P
P
R
S
L
Q
D
G
T
R
E
Site 31
T139
P
R
S
L
Q
D
G
T
R
E
G
F
G
H
S
Site 32
S146
T
R
E
G
F
G
H
S
T
S
L
K
V
P
L
Site 33
S148
E
G
F
G
H
S
T
S
L
K
V
P
L
A
R
Site 34
S160
L
A
R
S
L
Q
I
S
E
E
L
L
S
R
N
Site 35
S165
Q
I
S
E
E
L
L
S
R
N
Q
L
S
T
A
Site 36
S170
L
L
S
R
N
Q
L
S
T
A
A
S
L
G
P
Site 37
T171
L
S
R
N
Q
L
S
T
A
A
S
L
G
P
S
Site 38
S174
N
Q
L
S
T
A
A
S
L
G
P
S
G
L
Q
Site 39
S178
T
A
A
S
L
G
P
S
G
L
Q
N
H
G
Q
Site 40
S190
H
G
Q
H
L
I
L
S
R
E
A
S
W
A
K
Site 41
S194
L
I
L
S
R
E
A
S
W
A
K
P
H
Y
E
Site 42
Y200
A
S
W
A
K
P
H
Y
E
F
N
L
S
R
M
Site 43
S205
P
H
Y
E
F
N
L
S
R
M
K
F
R
G
N
Site 44
S216
F
R
G
N
G
A
L
S
N
I
S
D
L
P
F
Site 45
S219
N
G
A
L
S
N
I
S
D
L
P
F
L
A
E
Site 46
S246
Q
D
G
K
K
D
V
S
H
S
S
P
V
D
L
Site 47
S248
G
K
K
D
V
S
H
S
S
P
V
D
L
K
I
Site 48
S249
K
K
D
V
S
H
S
S
P
V
D
L
K
I
P
Site 49
S264
Q
V
R
G
M
D
L
S
W
E
S
R
T
G
D
Site 50
Y273
E
S
R
T
G
D
Q
Y
S
Y
S
S
L
V
M
Site 51
S274
S
R
T
G
D
Q
Y
S
Y
S
S
L
V
M
G
Site 52
Y275
R
T
G
D
Q
Y
S
Y
S
S
L
V
M
G
S
Site 53
S276
T
G
D
Q
Y
S
Y
S
S
L
V
M
G
S
Q
Site 54
S277
G
D
Q
Y
S
Y
S
S
L
V
M
G
S
Q
T
Site 55
S282
Y
S
S
L
V
M
G
S
Q
T
E
S
A
L
S
Site 56
T284
S
L
V
M
G
S
Q
T
E
S
A
L
S
K
K
Site 57
S286
V
M
G
S
Q
T
E
S
A
L
S
K
K
L
R
Site 58
S303
L
P
K
Q
S
R
K
S
M
L
D
A
G
P
D
Site 59
S311
M
L
D
A
G
P
D
S
W
G
S
D
A
E
Q
Site 60
S314
A
G
P
D
S
W
G
S
D
A
E
Q
S
T
S
Site 61
S319
W
G
S
D
A
E
Q
S
T
S
G
Q
P
Y
P
Site 62
S321
S
D
A
E
Q
S
T
S
G
Q
P
Y
P
T
S
Site 63
Y325
Q
S
T
S
G
Q
P
Y
P
T
S
D
Q
E
G
Site 64
S328
S
G
Q
P
Y
P
T
S
D
Q
E
G
D
P
G
Site 65
S336
D
Q
E
G
D
P
G
S
K
Q
P
R
K
K
R
Site 66
Y346
P
R
K
K
R
G
R
Y
R
Q
Y
N
S
E
I
Site 67
Y349
K
R
G
R
Y
R
Q
Y
N
S
E
I
L
E
E
Site 68
S359
E
I
L
E
E
A
I
S
V
V
M
S
G
K
M
Site 69
S363
E
A
I
S
V
V
M
S
G
K
M
S
V
S
K
Site 70
S369
M
S
G
K
M
S
V
S
K
A
Q
S
I
Y
G
Site 71
S373
M
S
V
S
K
A
Q
S
I
Y
G
I
P
H
S
Site 72
Y375
V
S
K
A
Q
S
I
Y
G
I
P
H
S
T
L
Site 73
S380
S
I
Y
G
I
P
H
S
T
L
E
Y
K
V
K
Site 74
T392
K
V
K
E
R
L
G
T
L
K
N
P
P
K
K
Site 75
S406
K
K
M
K
L
M
R
S
E
G
P
D
V
S
V
Site 76
S412
R
S
E
G
P
D
V
S
V
K
I
E
L
D
P
Site 77
S426
P
Q
G
E
A
A
Q
S
A
N
E
S
K
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation