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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO15B
Full Name:
Putative myosin-XVB
Alias:
Myosin XVBP;Unconventional myosin-15B
Type:
Mass (Da):
167118
Number AA:
1530
UniProt ID:
Q96JP2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
G
V
G
G
G
H
S
P
M
C
P
P
H
C
Site 2
T43
Q
P
R
Q
R
A
P
T
A
L
L
Q
P
D
A
Site 3
S83
L
P
R
P
P
G
R
S
A
P
Q
P
P
E
Y
Site 4
Y90
S
A
P
Q
P
P
E
Y
P
G
R
P
D
M
A
Site 5
T110
A
M
V
R
S
R
L
T
A
T
S
T
S
Q
A
Site 6
S113
R
S
R
L
T
A
T
S
T
S
Q
A
T
D
H
Site 7
T114
S
R
L
T
A
T
S
T
S
Q
A
T
D
H
T
Site 8
S115
R
L
T
A
T
S
T
S
Q
A
T
D
H
T
F
Site 9
T121
T
S
Q
A
T
D
H
T
F
L
Q
K
S
H
Y
Site 10
Y128
T
F
L
Q
K
S
H
Y
H
H
G
D
H
P
S
Site 11
S135
Y
H
H
G
D
H
P
S
Y
A
K
P
R
L
P
Site 12
Y136
H
H
G
D
H
P
S
Y
A
K
P
R
L
P
L
Site 13
Y151
P
V
F
T
V
R
H
Y
A
G
T
V
T
Y
Q
Site 14
T154
T
V
R
H
Y
A
G
T
V
T
Y
Q
V
H
K
Site 15
S188
S
Q
L
Q
L
V
G
S
L
F
Q
E
A
E
P
Site 16
S197
F
Q
E
A
E
P
Q
S
R
G
G
R
G
R
P
Site 17
T205
R
G
G
R
G
R
P
T
L
A
S
R
F
Q
Q
Site 18
S208
R
G
R
P
T
L
A
S
R
F
Q
Q
A
L
E
Site 19
Y227
R
L
G
R
S
H
V
Y
F
I
Q
C
L
T
P
Site 20
S293
S
E
G
Q
E
D
L
S
D
R
E
K
C
G
A
Site 21
S339
E
L
R
D
Q
Q
R
S
Q
A
L
V
D
L
H
Site 22
S354
R
S
F
H
T
C
I
S
R
Q
R
V
L
P
R
Site 23
Y375
G
F
Q
A
R
K
R
Y
L
R
R
R
A
A
L
Site 24
S412
G
R
W
Q
G
W
H
S
S
E
R
A
L
E
R
Site 25
S413
R
W
Q
G
W
H
S
S
E
R
A
L
E
R
V
Site 26
S422
R
A
L
E
R
V
P
S
M
E
L
G
R
L
E
Site 27
S443
V
M
L
K
T
A
E
S
H
R
D
A
L
A
G
Site 28
S451
H
R
D
A
L
A
G
S
I
T
E
C
L
P
P
Site 29
S465
P
E
V
P
A
R
P
S
L
T
L
P
A
D
I
Site 30
S489
A
I
G
F
Q
E
P
S
L
P
R
P
G
Q
P
Site 31
T502
Q
P
L
A
K
P
L
T
Q
L
D
G
D
N
P
Site 32
S527
L
R
L
L
G
D
G
S
L
E
S
W
Q
R
Q
Site 33
S530
L
G
D
G
S
L
E
S
W
Q
R
Q
I
M
G
Site 34
Y539
Q
R
Q
I
M
G
A
Y
L
V
R
Q
G
Q
C
Site 35
S600
K
P
L
L
K
F
V
S
D
Q
A
P
R
G
M
Site 36
S626
L
E
Q
S
Q
L
A
S
G
A
T
R
A
H
P
Site 37
T635
A
T
R
A
H
P
P
T
Q
L
E
W
L
A
G
Site 38
T654
R
M
A
L
D
V
F
T
F
S
E
E
C
Y
S
Site 39
S656
A
L
D
V
F
T
F
S
E
E
C
Y
S
A
E
Site 40
Y660
F
T
F
S
E
E
C
Y
S
A
E
V
E
S
W
Site 41
S661
T
F
S
E
E
C
Y
S
A
E
V
E
S
W
T
Site 42
T669
A
E
V
E
S
W
T
T
G
E
Q
L
A
G
W
Site 43
S691
E
A
P
P
R
G
W
S
V
S
L
H
S
R
D
Site 44
S693
P
P
R
G
W
S
V
S
L
H
S
R
D
A
W
Site 45
S714
D
F
V
L
D
L
I
S
Q
T
E
D
L
G
D
Site 46
S727
G
D
P
A
R
P
R
S
Y
P
I
T
P
L
G
Site 47
Y728
D
P
A
R
P
R
S
Y
P
I
T
P
L
G
S
Site 48
T731
R
P
R
S
Y
P
I
T
P
L
G
S
A
E
A
Site 49
S749
A
P
G
I
Q
A
P
S
L
P
P
G
P
P
P
Site 50
T761
P
P
P
G
P
A
P
T
L
P
S
R
D
H
T
Site 51
T768
T
L
P
S
R
D
H
T
G
E
V
Q
R
S
G
Site 52
S774
H
T
G
E
V
Q
R
S
G
S
L
D
G
F
L
Site 53
S776
G
E
V
Q
R
S
G
S
L
D
G
F
L
D
Q
Site 54
S794
P
V
I
S
S
G
L
S
D
L
E
Q
S
W
A
Site 55
S799
G
L
S
D
L
E
Q
S
W
A
L
S
S
R
M
Site 56
S803
L
E
Q
S
W
A
L
S
S
R
M
K
G
G
G
Site 57
S804
E
Q
S
W
A
L
S
S
R
M
K
G
G
G
A
Site 58
T815
G
G
G
A
I
G
P
T
Q
Q
G
Y
P
M
V
Site 59
Y819
I
G
P
T
Q
Q
G
Y
P
M
V
Y
P
G
M
Site 60
Y823
Q
Q
G
Y
P
M
V
Y
P
G
M
I
Q
M
P
Site 61
S866
P
P
Q
P
P
L
P
S
L
D
A
G
Q
L
A
Site 62
S899
T
A
Q
A
M
S
L
S
L
E
Q
Q
M
Q
Q
Site 63
S914
R
Q
Q
Q
A
R
A
S
E
A
A
S
Q
A
S
Site 64
S918
A
R
A
S
E
A
A
S
Q
A
S
P
S
A
V
Site 65
S921
S
E
A
A
S
Q
A
S
P
S
A
V
T
S
K
Site 66
S923
A
A
S
Q
A
S
P
S
A
V
T
S
K
P
R
Site 67
S927
A
S
P
S
A
V
T
S
K
P
R
K
P
P
T
Site 68
T934
S
K
P
R
K
P
P
T
P
P
E
K
P
Q
R
Site 69
S945
K
P
Q
R
D
L
G
S
E
G
G
C
L
R
E
Site 70
T953
E
G
G
C
L
R
E
T
S
E
E
A
E
D
R
Site 71
S954
G
G
C
L
R
E
T
S
E
E
A
E
D
R
P
Site 72
Y962
E
E
A
E
D
R
P
Y
Q
P
K
S
F
Q
Q
Site 73
S966
D
R
P
Y
Q
P
K
S
F
Q
Q
K
R
N
Y
Site 74
Y973
S
F
Q
Q
K
R
N
Y
F
Q
R
M
G
Q
P
Site 75
T983
R
M
G
Q
P
Q
I
T
V
R
T
M
K
P
P
Site 76
S1025
V
E
T
R
A
V
P
S
P
P
P
P
P
I
V
Site 77
T1070
G
P
A
Q
G
R
G
T
V
V
R
S
S
D
S
Site 78
S1074
G
R
G
T
V
V
R
S
S
D
S
K
P
K
R
Site 79
S1075
R
G
T
V
V
R
S
S
D
S
K
P
K
R
P
Site 80
S1077
T
V
V
R
S
S
D
S
K
P
K
R
P
Q
P
Site 81
Y1095
I
G
N
I
I
R
M
Y
Q
S
R
P
G
P
V
Site 82
S1109
V
P
V
P
V
Q
P
S
R
P
P
K
A
F
L
Site 83
S1136
L
G
I
N
G
A
H
S
S
P
P
M
L
S
P
Site 84
S1137
G
I
N
G
A
H
S
S
P
P
M
L
S
P
S
Site 85
S1142
H
S
S
P
P
M
L
S
P
S
P
G
K
G
P
Site 86
S1144
S
P
P
M
L
S
P
S
P
G
K
G
P
P
P
Site 87
S1166
A
P
L
Q
L
G
P
S
S
S
I
K
E
K
Q
Site 88
S1167
P
L
Q
L
G
P
S
S
S
I
K
E
K
Q
G
Site 89
S1168
L
Q
L
G
P
S
S
S
I
K
E
K
Q
G
P
Site 90
T1189
Q
K
L
P
I
A
H
T
P
P
P
P
P
A
P
Site 91
T1206
P
L
P
E
D
P
G
T
L
S
A
E
R
R
C
Site 92
S1208
P
E
D
P
G
T
L
S
A
E
R
R
C
L
T
Site 93
T1215
S
A
E
R
R
C
L
T
Q
P
V
E
D
Q
G
Site 94
S1237
P
S
G
S
V
C
F
S
Y
T
G
T
P
W
K
Site 95
Y1238
S
G
S
V
C
F
S
Y
T
G
T
P
W
K
L
Site 96
Y1253
F
L
R
K
E
V
F
Y
P
R
E
N
F
S
H
Site 97
Y1262
R
E
N
F
S
H
P
Y
Y
L
R
L
L
C
E
Site 98
Y1263
E
N
F
S
H
P
Y
Y
L
R
L
L
C
E
Q
Site 99
T1275
C
E
Q
I
L
R
D
T
F
S
E
S
C
I
R
Site 100
S1277
Q
I
L
R
D
T
F
S
E
S
C
I
R
I
S
Site 101
S1279
L
R
D
T
F
S
E
S
C
I
R
I
S
Q
N
Site 102
S1284
S
E
S
C
I
R
I
S
Q
N
E
R
R
K
M
Site 103
S1304
G
L
E
V
D
L
D
S
L
T
T
T
E
D
S
Site 104
T1306
E
V
D
L
D
S
L
T
T
T
E
D
S
V
K
Site 105
T1308
D
L
D
S
L
T
T
T
E
D
S
V
K
K
R
Site 106
S1311
S
L
T
T
T
E
D
S
V
K
K
R
I
V
V
Site 107
Y1327
A
R
D
N
W
A
N
Y
F
S
R
F
F
P
V
Site 108
S1335
F
S
R
F
F
P
V
S
G
E
S
G
S
D
V
Site 109
T1358
G
L
R
L
L
K
V
T
Q
G
P
G
L
R
P
Site 110
S1388
G
V
E
C
R
G
G
S
T
L
E
L
S
L
K
Site 111
T1389
V
E
C
R
G
G
S
T
L
E
L
S
L
K
S
Site 112
S1393
G
G
S
T
L
E
L
S
L
K
S
E
Q
L
V
Site 113
Y1426
E
L
K
K
D
S
G
Y
V
I
A
L
R
S
Y
Site 114
S1439
S
Y
I
T
D
N
C
S
L
L
S
F
H
R
G
Site 115
S1442
T
D
N
C
S
L
L
S
F
H
R
G
D
L
I
Site 116
S1465
E
P
G
W
Q
F
G
S
A
G
G
R
S
G
L
Site 117
S1487
P
A
A
A
P
D
F
S
F
S
K
E
Q
R
S
Site 118
S1489
A
A
P
D
F
S
F
S
K
E
Q
R
S
G
W
Site 119
S1494
S
F
S
K
E
Q
R
S
G
W
H
K
G
Q
L
Site 120
S1502
G
W
H
K
G
Q
L
S
N
G
E
P
G
L
A
Site 121
S1515
L
A
R
W
D
R
A
S
E
V
R
K
M
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation