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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZFYVE19
Full Name:
Zinc finger FYVE domain-containing protein 19
Alias:
FLJ14840; MLL partner containing FYVE domain; MPFYVE; ZFY19; zinc finger, FYVE domain containing 19
Type:
Mass (Da):
51530
Number AA:
471
UniProt ID:
Q96K21
International Prot ID:
IPI00386862
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y3
_
_
_
_
_
M
N
Y
D
S
Q
Q
P
P
L
Site 2
S5
_
_
_
M
N
Y
D
S
Q
Q
P
P
L
P
P
Site 3
Y15
P
P
L
P
P
L
P
Y
A
G
C
R
R
A
S
Site 4
S22
Y
A
G
C
R
R
A
S
G
F
P
A
L
G
R
Site 5
S49
G
Q
G
R
E
G
R
S
W
G
E
G
P
R
G
Site 6
S65
G
L
G
R
R
D
L
S
S
A
D
P
A
V
L
Site 7
S66
L
G
R
R
D
L
S
S
A
D
P
A
V
L
G
Site 8
T88
Y
G
C
A
V
K
F
T
L
F
K
K
E
Y
G
Site 9
Y94
F
T
L
F
K
K
E
Y
G
C
K
N
C
G
R
Site 10
S136
H
E
V
L
T
R
G
S
S
A
N
A
S
K
W
Site 11
S137
E
V
L
T
R
G
S
S
A
N
A
S
K
W
S
Site 12
S141
R
G
S
S
A
N
A
S
K
W
S
P
P
Q
N
Site 13
S144
S
A
N
A
S
K
W
S
P
P
Q
N
Y
K
K
Site 14
S163
L
E
A
K
Q
K
P
S
T
S
Q
S
Q
G
L
Site 15
S165
A
K
Q
K
P
S
T
S
Q
S
Q
G
L
T
R
Site 16
S167
Q
K
P
S
T
S
Q
S
Q
G
L
T
R
Q
D
Site 17
T171
T
S
Q
S
Q
G
L
T
R
Q
D
Q
M
I
A
Site 18
S195
N
K
P
K
L
V
P
S
Q
A
E
I
E
A
R
Site 19
S213
L
K
D
E
R
Q
G
S
I
P
S
T
Q
E
M
Site 20
S216
E
R
Q
G
S
I
P
S
T
Q
E
M
E
A
R
Site 21
T217
R
Q
G
S
I
P
S
T
Q
E
M
E
A
R
L
Site 22
S234
L
Q
G
R
V
L
P
S
Q
T
P
Q
P
A
H
Site 23
T236
G
R
V
L
P
S
Q
T
P
Q
P
A
H
H
T
Site 24
T243
T
P
Q
P
A
H
H
T
P
D
T
R
T
Q
A
Site 25
T246
P
A
H
H
T
P
D
T
R
T
Q
A
Q
Q
T
Site 26
S269
A
E
V
A
I
D
E
S
W
K
G
G
G
P
A
Site 27
S278
K
G
G
G
P
A
A
S
L
Q
N
D
L
N
Q
Site 28
S290
L
N
Q
G
G
P
G
S
T
N
S
K
R
Q
A
Site 29
S293
G
G
P
G
S
T
N
S
K
R
Q
A
N
W
S
Site 30
S300
S
K
R
Q
A
N
W
S
L
E
E
E
K
S
R
Site 31
S306
W
S
L
E
E
E
K
S
R
L
L
A
E
A
A
Site 32
T345
G
Q
D
P
E
R
V
T
L
Q
D
Y
R
L
P
Site 33
Y349
E
R
V
T
L
Q
D
Y
R
L
P
D
S
D
D
Site 34
S354
Q
D
Y
R
L
P
D
S
D
D
D
E
D
E
E
Site 35
T362
D
D
D
E
D
E
E
T
A
I
Q
R
V
L
Q
Site 36
S381
E
A
A
L
D
E
A
S
G
F
N
I
P
A
E
Site 37
T395
E
Q
A
S
R
P
W
T
Q
P
R
G
A
E
P
Site 38
T459
F
E
L
K
E
H
Q
T
S
A
Y
S
P
P
R
Site 39
S460
E
L
K
E
H
Q
T
S
A
Y
S
P
P
R
A
Site 40
Y462
K
E
H
Q
T
S
A
Y
S
P
P
R
A
G
Q
Site 41
S463
E
H
Q
T
S
A
Y
S
P
P
R
A
G
Q
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation