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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCNS1
Full Name:
Potassium voltage-gated channel subfamily S member 1
Alias:
Delayed-rectifier K(+) channel alpha subunit 1;Voltage-gated potassium channel subunit Kv9.1
Type:
Mass (Da):
58372
Number AA:
526
UniProt ID:
Q96KK3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
L
M
L
L
V
R
G
T
H
Y
E
N
L
R
S
Site 2
Y11
L
L
V
R
G
T
H
Y
E
N
L
R
S
K
V
Site 3
S16
T
H
Y
E
N
L
R
S
K
V
V
L
P
T
P
Site 4
T22
R
S
K
V
V
L
P
T
P
L
G
G
R
S
T
Site 5
T29
T
P
L
G
G
R
S
T
E
T
F
V
S
E
F
Site 6
T31
L
G
G
R
S
T
E
T
F
V
S
E
F
P
G
Site 7
S34
R
S
T
E
T
F
V
S
E
F
P
G
P
D
T
Site 8
T41
S
E
F
P
G
P
D
T
G
I
R
W
R
R
S
Site 9
S48
T
G
I
R
W
R
R
S
D
E
A
L
R
V
N
Site 10
S64
G
G
V
R
R
Q
L
S
A
R
A
L
A
R
F
Site 11
S84
G
R
L
Q
A
A
A
S
E
E
Q
A
R
R
L
Site 12
Y95
A
R
R
L
C
D
D
Y
D
E
A
A
R
E
F
Site 13
Y103
D
E
A
A
R
E
F
Y
F
D
R
H
P
G
F
Site 14
S113
R
H
P
G
F
F
L
S
L
L
H
F
Y
R
T
Site 15
Y140
A
F
G
Q
E
A
D
Y
W
G
L
G
E
N
A
Site 16
Y156
A
A
C
C
R
A
R
Y
L
E
R
R
L
T
Q
Site 17
T162
R
Y
L
E
R
R
L
T
Q
P
H
A
W
D
E
Site 18
S171
P
H
A
W
D
E
D
S
D
T
P
S
S
V
D
Site 19
T173
A
W
D
E
D
S
D
T
P
S
S
V
D
P
C
Site 20
S175
D
E
D
S
D
T
P
S
S
V
D
P
C
P
D
Site 21
S176
E
D
S
D
T
P
S
S
V
D
P
C
P
D
E
Site 22
S185
D
P
C
P
D
E
I
S
D
V
Q
R
E
L
A
Site 23
Y194
V
Q
R
E
L
A
R
Y
G
A
A
R
C
G
R
Site 24
T209
L
R
R
R
L
W
L
T
M
E
N
P
G
Y
S
Site 25
Y215
L
T
M
E
N
P
G
Y
S
L
P
S
K
L
F
Site 26
S216
T
M
E
N
P
G
Y
S
L
P
S
K
L
F
S
Site 27
S219
N
P
G
Y
S
L
P
S
K
L
F
S
C
V
S
Site 28
Y245
C
I
H
S
L
P
E
Y
Q
A
R
E
A
A
A
Site 29
S262
A
A
V
A
A
G
R
S
P
E
G
V
R
D
D
Site 30
S296
S
R
L
L
L
A
P
S
T
R
N
F
F
C
H
Site 31
T297
R
L
L
L
A
P
S
T
R
N
F
F
C
H
P
Site 32
S359
V
L
K
L
A
R
H
S
T
G
L
R
S
L
G
Site 33
T360
L
K
L
A
R
H
S
T
G
L
R
S
L
G
A
Site 34
S364
R
H
S
T
G
L
R
S
L
G
A
T
L
K
H
Site 35
T368
G
L
R
S
L
G
A
T
L
K
H
S
Y
R
E
Site 36
Y395
S
V
F
S
G
V
A
Y
T
A
E
K
E
E
D
Site 37
S477
L
E
A
A
V
R
N
S
N
H
Q
E
F
E
D
Site 38
S487
Q
E
F
E
D
L
L
S
S
I
D
G
V
S
E
Site 39
S488
E
F
E
D
L
L
S
S
I
D
G
V
S
E
A
Site 40
S493
L
S
S
I
D
G
V
S
E
A
S
L
E
T
S
Site 41
S496
I
D
G
V
S
E
A
S
L
E
T
S
R
E
T
Site 42
S500
S
E
A
S
L
E
T
S
R
E
T
S
Q
E
G
Site 43
T503
S
L
E
T
S
R
E
T
S
Q
E
G
Q
S
A
Site 44
S504
L
E
T
S
R
E
T
S
Q
E
G
Q
S
A
D
Site 45
S509
E
T
S
Q
E
G
Q
S
A
D
L
E
S
Q
A
Site 46
S514
G
Q
S
A
D
L
E
S
Q
A
P
S
E
P
P
Site 47
S518
D
L
E
S
Q
A
P
S
E
P
P
H
P
Q
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation