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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNDP1
Full Name:
Beta-Ala-His dipeptidase
Alias:
Beta-Ala-His dipeptidase; Carnosinase 1; CN1; CNDP dipeptidase 1; CPGL2; EC 3.4.13.20; Glutamate carboxypeptidase-like protein 2; HsT2308; Metallopeptidase M20 family; MGC10825
Type:
Amino Acid Metabolism - histidine; Protease; Other Amino Acids Metabolism - beta-alanine; EC 3.4.13.20
Mass (Da):
56692
Number AA:
507
UniProt ID:
Q96KN2
International Prot ID:
IPI00064667
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004180
GO:0008237
GO:0046983
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
L
L
E
R
G
M
F
S
S
P
S
P
P
P
A
Site 2
S27
L
E
R
G
M
F
S
S
P
S
P
P
P
A
L
Site 3
S29
R
G
M
F
S
S
P
S
P
P
P
A
L
L
E
Site 4
S61
K
E
W
V
A
I
E
S
D
S
V
Q
P
V
P
Site 5
S63
W
V
A
I
E
S
D
S
V
Q
P
V
P
R
F
Site 6
S94
R
L
G
A
R
V
A
S
V
D
M
G
P
Q
Q
Site 7
S107
Q
Q
L
P
D
G
Q
S
L
P
I
P
P
V
I
Site 8
T126
G
S
D
P
T
K
G
T
V
C
F
Y
G
H
L
Site 9
T146
D
R
G
D
G
W
L
T
D
P
Y
V
L
T
E
Site 10
Y149
D
G
W
L
T
D
P
Y
V
L
T
E
V
D
G
Site 11
T152
L
T
D
P
Y
V
L
T
E
V
D
G
K
L
Y
Site 12
Y159
T
E
V
D
G
K
L
Y
G
R
G
A
T
D
N
Site 13
T164
K
L
Y
G
R
G
A
T
D
N
K
G
P
V
L
Site 14
S219
K
E
K
D
R
F
F
S
G
V
D
Y
I
V
I
Site 15
S233
I
S
D
N
L
W
I
S
Q
R
K
P
A
I
T
Site 16
T240
S
Q
R
K
P
A
I
T
Y
G
T
R
G
N
S
Site 17
Y241
Q
R
K
P
A
I
T
Y
G
T
R
G
N
S
Y
Site 18
S247
T
Y
G
T
R
G
N
S
Y
F
M
V
E
V
K
Site 19
Y248
Y
G
T
R
G
N
S
Y
F
M
V
E
V
K
C
Site 20
T264
D
Q
D
F
H
S
G
T
F
G
G
I
L
H
E
Site 21
T303
Y
D
E
V
V
P
L
T
E
E
E
I
N
T
Y
Site 22
T309
L
T
E
E
E
I
N
T
Y
K
A
I
H
L
D
Site 23
Y310
T
E
E
E
I
N
T
Y
K
A
I
H
L
D
L
Site 24
Y320
I
H
L
D
L
E
E
Y
R
N
S
S
R
V
E
Site 25
S323
D
L
E
E
Y
R
N
S
S
R
V
E
K
F
L
Site 26
S324
L
E
E
Y
R
N
S
S
R
V
E
K
F
L
F
Site 27
T333
V
E
K
F
L
F
D
T
K
E
E
I
L
M
H
Site 28
S348
L
W
R
Y
P
S
L
S
I
H
G
I
E
G
A
Site 29
T361
G
A
F
D
E
P
G
T
K
T
V
I
P
G
R
Site 30
T363
F
D
E
P
G
T
K
T
V
I
P
G
R
V
I
Site 31
T391
S
A
V
E
K
Q
V
T
R
H
L
E
D
V
F
Site 32
S399
R
H
L
E
D
V
F
S
K
R
N
S
S
N
K
Site 33
S403
D
V
F
S
K
R
N
S
S
N
K
M
V
V
S
Site 34
S404
V
F
S
K
R
N
S
S
N
K
M
V
V
S
M
Site 35
Y427
A
N
I
D
D
T
Q
Y
L
A
A
K
R
A
I
Site 36
T436
A
A
K
R
A
I
R
T
V
F
G
T
E
P
D
Site 37
T440
A
I
R
T
V
F
G
T
E
P
D
M
I
R
D
Site 38
S449
P
D
M
I
R
D
G
S
T
I
P
I
A
K
M
Site 39
S479
A
V
D
D
G
E
H
S
Q
N
E
K
I
N
R
Site 40
Y489
E
K
I
N
R
W
N
Y
I
E
G
T
K
L
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation