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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXOC2
Full Name:
Exocyst complex component 2
Alias:
Exocyst complex component Sec5; FLJ11026; SEC5L1; Sec5p
Type:
Vesicle protein
Mass (Da):
104066
Number AA:
924
UniProt ID:
Q96KP1
International Prot ID:
IPI00783559
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0017016
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006887
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
P
P
L
V
T
G
I
S
P
N
E
G
I
P
W
Site 2
T25
G
I
P
W
T
K
V
T
I
R
G
E
N
L
G
Site 3
T33
I
R
G
E
N
L
G
T
G
P
T
D
L
I
G
Site 4
T78
K
G
D
I
I
V
T
T
K
S
G
G
R
G
T
Site 5
S80
D
I
I
V
T
T
K
S
G
G
R
G
T
S
T
Site 6
T85
T
K
S
G
G
R
G
T
S
T
V
S
F
K
L
Site 7
S86
K
S
G
G
R
G
T
S
T
V
S
F
K
L
L
Site 8
T87
S
G
G
R
G
T
S
T
V
S
F
K
L
L
K
Site 9
S89
G
R
G
T
S
T
V
S
F
K
L
L
K
P
E
Site 10
Y113
V
W
V
D
E
M
N
Y
Y
D
M
R
T
D
R
Site 11
Y114
W
V
D
E
M
N
Y
Y
D
M
R
T
D
R
N
Site 12
S128
N
K
G
I
P
P
L
S
L
R
P
A
N
P
L
Site 13
S142
L
G
I
E
I
E
K
S
K
F
S
Q
K
D
L
Site 14
S157
E
M
L
F
H
G
M
S
A
D
F
T
S
E
N
Site 15
T161
H
G
M
S
A
D
F
T
S
E
N
F
S
A
A
Site 16
S162
G
M
S
A
D
F
T
S
E
N
F
S
A
A
W
Site 17
Y170
E
N
F
S
A
A
W
Y
L
I
E
N
H
S
N
Site 18
S198
K
R
Q
A
N
K
K
S
E
G
S
L
A
Y
V
Site 19
S201
A
N
K
K
S
E
G
S
L
A
Y
V
K
G
G
Site 20
Y204
K
S
E
G
S
L
A
Y
V
K
G
G
L
S
T
Site 21
T231
Q
K
L
E
A
D
G
T
E
K
V
E
G
S
M
Site 22
T239
E
K
V
E
G
S
M
T
Q
K
L
E
N
V
L
Site 23
S250
E
N
V
L
N
R
A
S
N
T
A
D
T
L
F
Site 24
T252
V
L
N
R
A
S
N
T
A
D
T
L
F
Q
E
Site 25
T255
R
A
S
N
T
A
D
T
L
F
Q
E
V
L
G
Site 26
S269
G
R
K
D
K
A
D
S
T
R
N
A
L
N
V
Site 27
Y299
R
N
I
Q
K
G
D
Y
D
V
V
I
N
D
Y
Site 28
Y306
Y
D
V
V
I
N
D
Y
E
K
A
K
S
L
F
Site 29
S311
N
D
Y
E
K
A
K
S
L
F
G
K
T
E
V
Site 30
Y324
E
V
Q
V
F
K
K
Y
Y
A
E
V
E
T
R
Site 31
Y325
V
Q
V
F
K
K
Y
Y
A
E
V
E
T
R
I
Site 32
T346
L
L
D
K
L
L
E
T
P
S
T
L
H
D
Q
Site 33
S348
D
K
L
L
E
T
P
S
T
L
H
D
Q
K
R
Site 34
T349
K
L
L
E
T
P
S
T
L
H
D
Q
K
R
Y
Site 35
Y356
T
L
H
D
Q
K
R
Y
I
R
Y
L
S
D
L
Site 36
Y359
D
Q
K
R
Y
I
R
Y
L
S
D
L
H
A
S
Site 37
S361
K
R
Y
I
R
Y
L
S
D
L
H
A
S
G
D
Site 38
Y392
M
H
S
C
K
E
G
Y
V
K
D
L
K
G
N
Site 39
S404
K
G
N
P
G
L
H
S
P
M
L
D
L
D
N
Site 40
T413
M
L
D
L
D
N
D
T
R
P
S
V
L
G
H
Site 41
S416
L
D
N
D
T
R
P
S
V
L
G
H
L
S
Q
Site 42
S422
P
S
V
L
G
H
L
S
Q
T
A
S
L
K
R
Site 43
S426
G
H
L
S
Q
T
A
S
L
K
R
G
S
S
F
Site 44
S431
T
A
S
L
K
R
G
S
S
F
Q
S
G
R
D
Site 45
S432
A
S
L
K
R
G
S
S
F
Q
S
G
R
D
D
Site 46
S435
K
R
G
S
S
F
Q
S
G
R
D
D
T
W
R
Site 47
T440
F
Q
S
G
R
D
D
T
W
R
Y
K
T
P
H
Site 48
Y443
G
R
D
D
T
W
R
Y
K
T
P
H
R
V
A
Site 49
T445
D
D
T
W
R
Y
K
T
P
H
R
V
A
F
V
Site 50
S461
K
L
T
K
L
V
L
S
Q
L
P
N
F
W
K
Site 51
S477
W
I
S
Y
V
N
G
S
L
F
S
E
T
A
E
Site 52
T482
N
G
S
L
F
S
E
T
A
E
K
S
G
Q
I
Site 53
S486
F
S
E
T
A
E
K
S
G
Q
I
E
R
S
K
Site 54
S492
K
S
G
Q
I
E
R
S
K
N
V
R
Q
R
Q
Site 55
S525
R
G
A
L
L
P
L
S
I
R
D
G
E
A
K
Site 56
Y534
R
D
G
E
A
K
Q
Y
G
G
W
E
V
K
C
Site 57
T590
R
V
R
C
V
M
A
T
L
Q
H
T
A
E
E
Site 58
S616
V
D
N
E
G
L
T
S
L
P
C
Q
F
E
Q
Site 59
S644
E
C
K
P
G
E
A
S
V
F
Q
Q
P
K
T
Site 60
T651
S
V
F
Q
Q
P
K
T
Q
E
E
V
C
Q
L
Site 61
S674
I
Y
C
L
E
Q
L
S
T
K
P
D
A
D
I
Site 62
T675
Y
C
L
E
Q
L
S
T
K
P
D
A
D
I
D
Site 63
T683
K
P
D
A
D
I
D
T
T
H
L
S
V
D
V
Site 64
S687
D
I
D
T
T
H
L
S
V
D
V
S
S
P
D
Site 65
S691
T
H
L
S
V
D
V
S
S
P
D
L
F
G
S
Site 66
S698
S
S
P
D
L
F
G
S
I
H
E
D
F
S
L
Site 67
S704
G
S
I
H
E
D
F
S
L
T
S
E
Q
R
L
Site 68
S707
H
E
D
F
S
L
T
S
E
Q
R
L
L
I
V
Site 69
Y763
D
Q
R
L
F
E
N
Y
I
E
L
K
A
D
P
Site 70
Y780
G
S
L
E
P
G
I
Y
A
G
Y
F
D
W
K
Site 71
Y783
E
P
G
I
Y
A
G
Y
F
D
W
K
D
C
L
Site 72
T793
W
K
D
C
L
P
P
T
G
V
R
N
Y
L
K
Site 73
Y798
P
P
T
G
V
R
N
Y
L
K
E
A
L
V
N
Site 74
S837
E
A
V
S
E
E
L
S
R
L
M
Q
C
V
S
Site 75
S844
S
R
L
M
Q
C
V
S
S
F
S
K
N
G
A
Site 76
S845
R
L
M
Q
C
V
S
S
F
S
K
N
G
A
L
Site 77
Y868
L
R
D
T
V
A
V
Y
L
T
P
E
S
K
S
Site 78
T870
D
T
V
A
V
Y
L
T
P
E
S
K
S
S
F
Site 79
S873
A
V
Y
L
T
P
E
S
K
S
S
F
K
Q
A
Site 80
S876
L
T
P
E
S
K
S
S
F
K
Q
A
L
E
A
Site 81
S889
E
A
L
P
Q
L
S
S
G
A
D
K
K
L
L
Site 82
S905
E
L
L
N
K
F
K
S
S
M
H
L
Q
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation