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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
calreticulin 3
Full Name:
Calreticulin-3
Alias:
CALR3; Calreticulin 2; Calreticulin 3; Calreticulin-2; Cancer/testis antigen 93; CRT2; CRTC3; CT93; FLJ25355; MGC26577
Type:
Chaperone
Mass (Da):
44996
Number AA:
384
UniProt ID:
Q96L12
International Prot ID:
IPI00153053
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005788
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005529
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T41
R
N
R
W
L
Q
S
T
N
D
S
R
F
G
H
Site 2
S44
W
L
Q
S
T
N
D
S
R
F
G
H
F
R
L
Site 3
S52
R
F
G
H
F
R
L
S
S
G
K
F
Y
G
H
Site 4
S53
F
G
H
F
R
L
S
S
G
K
F
Y
G
H
K
Site 5
Y57
R
L
S
S
G
K
F
Y
G
H
K
E
K
D
K
Site 6
T68
E
K
D
K
G
L
Q
T
T
Q
N
G
R
F
Y
Site 7
T69
K
D
K
G
L
Q
T
T
Q
N
G
R
F
Y
A
Site 8
Y75
T
T
Q
N
G
R
F
Y
A
I
S
A
R
F
K
Site 9
S78
N
G
R
F
Y
A
I
S
A
R
F
K
P
F
S
Site 10
S85
S
A
R
F
K
P
F
S
N
K
G
K
T
L
V
Site 11
T90
P
F
S
N
K
G
K
T
L
V
I
Q
Y
T
V
Site 12
T96
K
T
L
V
I
Q
Y
T
V
K
H
E
Q
K
M
Site 13
Y109
K
M
D
C
G
G
G
Y
I
K
V
F
P
A
D
Site 14
Y128
N
L
N
G
K
S
Q
Y
Y
I
M
F
G
P
D
Site 15
Y129
L
N
G
K
S
Q
Y
Y
I
M
F
G
P
D
I
Site 16
Y154
I
L
H
F
K
N
K
Y
H
E
N
K
K
L
I
Site 17
Y182
I
L
R
P
D
L
S
Y
D
V
K
I
D
G
Q
Site 18
S190
D
V
K
I
D
G
Q
S
I
E
S
G
S
I
E
Site 19
S204
E
Y
D
W
N
L
T
S
L
K
K
E
T
S
P
Site 20
T209
L
T
S
L
K
K
E
T
S
P
A
E
S
K
D
Site 21
S210
T
S
L
K
K
E
T
S
P
A
E
S
K
D
W
Site 22
S214
K
E
T
S
P
A
E
S
K
D
W
E
Q
T
K
Site 23
S236
E
K
H
F
L
D
A
S
T
S
K
Q
S
D
W
Site 24
T237
K
H
F
L
D
A
S
T
S
K
Q
S
D
W
N
Site 25
S238
H
F
L
D
A
S
T
S
K
Q
S
D
W
N
G
Site 26
Y261
P
M
L
Q
K
P
P
Y
Q
D
G
L
K
P
E
Site 27
Y285
R
K
M
K
N
T
D
Y
L
T
Q
Y
D
L
S
Site 28
T287
M
K
N
T
D
Y
L
T
Q
Y
D
L
S
E
F
Site 29
Y289
N
T
D
Y
L
T
Q
Y
D
L
S
E
F
E
N
Site 30
Y324
L
I
T
D
D
E
E
Y
A
D
N
F
G
K
A
Site 31
S365
E
E
E
E
E
L
L
S
G
K
I
N
R
H
E
Site 32
Y374
K
I
N
R
H
E
H
Y
F
N
Q
F
H
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation