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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX27
Full Name:
Sorting nexin-27
Alias:
KIAA0488; MGC20471; MY014; Sorting nexin family member 27
Type:
Vesicle protein
Mass (Da):
61265
Number AA:
541
UniProt ID:
Q96L92
International Prot ID:
IPI00328097
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005769
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
D
G
E
G
I
H
P
S
A
P
H
R
N
G
G
Site 2
S26
G
G
G
G
G
G
G
S
G
L
H
C
A
G
N
Site 3
S49
R
V
V
R
I
V
K
S
E
S
G
Y
G
F
N
Site 4
S51
V
R
I
V
K
S
E
S
G
Y
G
F
N
V
R
Site 5
Y53
I
V
K
S
E
S
G
Y
G
F
N
V
R
G
Q
Site 6
S62
F
N
V
R
G
Q
V
S
E
G
G
Q
L
R
S
Site 7
S69
S
E
G
G
Q
L
R
S
I
N
G
E
L
Y
A
Site 8
Y75
R
S
I
N
G
E
L
Y
A
P
L
Q
H
V
S
Site 9
S82
Y
A
P
L
Q
H
V
S
A
V
L
P
G
G
A
Site 10
S146
E
A
D
N
L
D
P
S
D
D
S
L
G
Q
S
Site 11
S149
N
L
D
P
S
D
D
S
L
G
Q
S
F
Y
D
Site 12
S153
S
D
D
S
L
G
Q
S
F
Y
D
Y
T
E
K
Site 13
Y155
D
S
L
G
Q
S
F
Y
D
Y
T
E
K
Q
A
Site 14
Y157
L
G
Q
S
F
Y
D
Y
T
E
K
Q
A
V
P
Site 15
T158
G
Q
S
F
Y
D
Y
T
E
K
Q
A
V
P
I
Site 16
S166
E
K
Q
A
V
P
I
S
V
P
R
Y
K
H
V
Site 17
Y170
V
P
I
S
V
P
R
Y
K
H
V
E
Q
N
G
Site 18
Y183
N
G
E
K
F
V
V
Y
N
V
Y
M
A
G
R
Site 19
Y186
K
F
V
V
Y
N
V
Y
M
A
G
R
Q
L
C
Site 20
S194
M
A
G
R
Q
L
C
S
K
R
Y
R
E
F
A
Site 21
T215
K
R
E
F
A
N
F
T
F
P
R
L
P
G
K
Site 22
S226
L
P
G
K
W
P
F
S
L
S
E
Q
Q
L
D
Site 23
S228
G
K
W
P
F
S
L
S
E
Q
Q
L
D
A
R
Site 24
Y242
R
R
R
G
L
E
E
Y
L
E
K
V
C
S
I
Site 25
S248
E
Y
L
E
K
V
C
S
I
R
V
I
G
E
S
Site 26
S263
D
I
M
Q
E
F
L
S
E
S
D
E
N
Y
N
Site 27
S265
M
Q
E
F
L
S
E
S
D
E
N
Y
N
G
V
Site 28
Y269
L
S
E
S
D
E
N
Y
N
G
V
S
D
V
E
Site 29
T288
L
P
D
G
T
T
V
T
V
R
V
K
K
N
S
Site 30
S295
T
V
R
V
K
K
N
S
T
T
D
Q
V
Y
Q
Site 31
T296
V
R
V
K
K
N
S
T
T
D
Q
V
Y
Q
A
Site 32
T297
R
V
K
K
N
S
T
T
D
Q
V
Y
Q
A
I
Site 33
Y301
N
S
T
T
D
Q
V
Y
Q
A
I
A
A
K
V
Site 34
Y342
N
E
F
P
H
K
L
Y
I
Q
N
Y
T
S
A
Site 35
Y346
H
K
L
Y
I
Q
N
Y
T
S
A
V
P
G
T
Site 36
Y379
D
N
D
L
A
V
T
Y
F
F
H
Q
A
V
D
Site 37
Y392
V
D
D
V
K
K
G
Y
I
K
A
E
E
K
S
Site 38
Y400
I
K
A
E
E
K
S
Y
Q
L
Q
K
L
Y
E
Site 39
Y406
S
Y
Q
L
Q
K
L
Y
E
Q
R
K
M
V
M
Site 40
Y414
E
Q
R
K
M
V
M
Y
L
N
M
L
R
T
C
Site 41
Y424
M
L
R
T
C
E
G
Y
N
E
I
I
F
P
H
Site 42
T444
R
R
K
G
H
V
I
T
A
I
S
I
T
H
F
Site 43
T479
D
E
M
Q
R
W
D
T
D
E
E
G
M
A
F
Site 44
Y490
G
M
A
F
C
F
E
Y
A
R
G
E
K
K
P
Site 45
T504
P
R
W
V
K
I
F
T
P
Y
F
N
Y
M
H
Site 46
Y506
W
V
K
I
F
T
P
Y
F
N
Y
M
H
E
C
Site 47
S534
N
I
F
Q
M
A
R
S
Q
Q
R
D
V
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation