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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IFT74
Full Name:
Intraflagellar transport protein 74 homolog
Alias:
Capillary morphogenesis protein 1; CCDC2; CMG1; CMG-1; Coiled-coil domain containing 2; Coiled-coil domain-containing protein 2; FLJ22621; Intraflagellar transport 74
Type:
Vesicle protein
Mass (Da):
69239
Number AA:
600
UniProt ID:
Q96LB3
International Prot ID:
IPI00018090
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016023
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
N
H
K
S
S
A
A
R
P
V
S
Site 2
S14
S
S
A
A
R
P
V
S
R
G
G
V
G
L
T
Site 3
T21
S
R
G
G
V
G
L
T
G
R
P
P
S
G
I
Site 4
S26
G
L
T
G
R
P
P
S
G
I
R
P
L
S
G
Site 5
S32
P
S
G
I
R
P
L
S
G
N
I
R
V
A
T
Site 6
T45
A
T
A
M
P
P
G
T
A
R
P
G
S
R
G
Site 7
S50
P
G
T
A
R
P
G
S
R
G
C
P
I
G
T
Site 8
T57
S
R
G
C
P
I
G
T
G
G
V
L
S
S
Q
Site 9
S63
G
T
G
G
V
L
S
S
Q
I
K
V
A
H
R
Site 10
T73
K
V
A
H
R
P
V
T
Q
Q
G
L
T
G
M
Site 11
T82
Q
G
L
T
G
M
K
T
G
T
K
G
P
Q
R
Site 12
S95
Q
R
Q
I
L
D
K
S
Y
Y
L
G
L
L
R
Site 13
Y96
R
Q
I
L
D
K
S
Y
Y
L
G
L
L
R
S
Site 14
Y97
Q
I
L
D
K
S
Y
Y
L
G
L
L
R
S
K
Site 15
S103
Y
Y
L
G
L
L
R
S
K
I
S
E
L
T
T
Site 16
T110
S
K
I
S
E
L
T
T
E
V
N
K
L
Q
K
Site 17
Y129
Y
N
Q
E
N
S
V
Y
L
S
Y
E
K
R
A
Site 18
S131
Q
E
N
S
V
Y
L
S
Y
E
K
R
A
E
T
Site 19
T138
S
Y
E
K
R
A
E
T
L
A
V
E
I
K
E
Site 20
Y153
L
Q
G
Q
L
A
D
Y
N
M
L
V
D
K
L
Site 21
Y173
M
E
E
V
M
N
D
Y
N
M
L
K
A
Q
N
Site 22
T184
K
A
Q
N
D
R
E
T
Q
S
L
D
V
I
F
Site 23
S186
Q
N
D
R
E
T
Q
S
L
D
V
I
F
T
E
Site 24
S203
A
K
E
K
Q
I
R
S
V
E
E
E
I
E
Q
Site 25
T215
I
E
Q
E
K
Q
A
T
D
D
I
I
K
N
M
Site 26
Y230
S
F
E
N
Q
V
K
Y
L
E
M
K
T
T
N
Site 27
T236
K
Y
L
E
M
K
T
T
N
E
K
L
L
Q
E
Site 28
T246
K
L
L
Q
E
L
D
T
L
Q
Q
Q
L
D
S
Site 29
S253
T
L
Q
Q
Q
L
D
S
Q
N
M
K
K
E
S
Site 30
S260
S
Q
N
M
K
K
E
S
L
E
A
E
I
A
H
Site 31
S268
L
E
A
E
I
A
H
S
Q
V
K
Q
E
A
V
Site 32
Y282
V
L
L
H
E
K
L
Y
E
L
E
S
H
R
D
Site 33
S286
E
K
L
Y
E
L
E
S
H
R
D
Q
M
I
A
Site 34
S297
Q
M
I
A
E
D
K
S
I
G
S
P
M
E
E
Site 35
S300
A
E
D
K
S
I
G
S
P
M
E
E
R
E
K
Site 36
T327
A
S
M
E
R
Q
L
T
D
T
K
E
K
I
N
Site 37
T329
M
E
R
Q
L
T
D
T
K
E
K
I
N
Q
F
Site 38
Y358
Q
G
E
M
N
Q
K
Y
K
E
L
K
K
R
E
Site 39
T370
K
R
E
E
H
M
D
T
F
I
E
T
F
E
E
Site 40
T374
H
M
D
T
F
I
E
T
F
E
E
T
K
N
Q
Site 41
S401
V
A
L
L
E
H
C
S
R
N
I
N
R
I
E
Site 42
S411
I
N
R
I
E
Q
I
S
S
I
T
N
Q
E
L
Site 43
S412
N
R
I
E
Q
I
S
S
I
T
N
Q
E
L
K
Site 44
S429
Q
D
D
L
N
F
K
S
T
E
V
Q
K
S
Q
Site 45
S435
K
S
T
E
V
Q
K
S
Q
S
T
A
Q
N
L
Site 46
S461
Q
K
M
E
L
L
E
S
K
M
T
E
E
Q
H
Site 47
T464
E
L
L
E
S
K
M
T
E
E
Q
H
S
L
K
Site 48
S469
K
M
T
E
E
Q
H
S
L
K
S
K
I
K
Q
Site 49
S472
E
E
Q
H
S
L
K
S
K
I
K
Q
M
T
T
Site 50
S492
N
D
L
P
A
L
K
S
S
G
E
E
K
I
K
Site 51
T510
Q
E
R
M
I
L
S
T
H
R
N
A
F
K
K
Site 52
T531
I
E
Y
E
A
L
K
T
Q
L
Q
E
N
E
T
Site 53
S540
L
Q
E
N
E
T
H
S
Q
L
T
N
L
E
R
Site 54
T565
A
M
K
E
F
I
A
T
K
S
Q
E
S
D
Y
Site 55
S567
K
E
F
I
A
T
K
S
Q
E
S
D
Y
Q
P
Site 56
Y572
T
K
S
Q
E
S
D
Y
Q
P
I
K
K
N
V
Site 57
T589
Q
I
A
E
Y
N
K
T
I
V
D
A
L
H
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation