KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SIGLEC10
Full Name:
Sialic acid-binding Ig-like lectin 10
Alias:
MGC126774; PRO940; Sialic acid binding Ig-like lectin 10; Sialic acid binding Ig-like lectin 10 Ig-like lectin 7; SIG10; Siglec10; SIGLEC-10; Siglec-like gene 2; Siglec-like protein 2; SILA; SLG2
Type:
Adhesion protein
Mass (Da):
76592
Number AA:
697
UniProt ID:
Q96LC7
International Prot ID:
IPI00064982
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
L
L
P
L
L
L
S
S
L
L
G
G
S
Q
Site 2
S9
L
L
P
L
L
L
S
S
L
L
G
G
S
Q
A
Site 3
S14
L
S
S
L
L
G
G
S
Q
A
M
D
G
R
F
Site 4
Y57
W
T
G
S
T
P
A
Y
G
Y
W
F
K
A
V
Site 5
T250
I
S
I
S
R
D
N
T
P
A
L
E
P
Q
P
Site 6
T322
A
G
D
S
G
R
Y
T
C
R
A
E
N
R
L
Site 7
S331
R
A
E
N
R
L
G
S
Q
Q
R
A
L
D
L
Site 8
S339
Q
Q
R
A
L
D
L
S
V
Q
Y
P
P
E
N
Site 9
T579
K
I
L
P
K
R
R
T
Q
T
E
T
P
R
P
Site 10
T581
L
P
K
R
R
T
Q
T
E
T
P
R
P
R
F
Site 11
T583
K
R
R
T
Q
T
E
T
P
R
P
R
F
S
R
Site 12
S589
E
T
P
R
P
R
F
S
R
H
S
T
I
L
D
Site 13
S592
R
P
R
F
S
R
H
S
T
I
L
D
Y
I
N
Site 14
T593
P
R
F
S
R
H
S
T
I
L
D
Y
I
N
V
Site 15
Y597
R
H
S
T
I
L
D
Y
I
N
V
V
P
T
A
Site 16
T616
Q
K
R
N
Q
K
A
T
P
N
S
P
R
T
P
Site 17
S619
N
Q
K
A
T
P
N
S
P
R
T
P
L
P
P
Site 18
T622
A
T
P
N
S
P
R
T
P
L
P
P
G
A
P
Site 19
S630
P
L
P
P
G
A
P
S
P
E
S
K
K
N
Q
Site 20
S633
P
G
A
P
S
P
E
S
K
K
N
Q
K
K
Q
Site 21
Y641
K
K
N
Q
K
K
Q
Y
Q
L
P
S
F
P
E
Site 22
S645
K
K
Q
Y
Q
L
P
S
F
P
E
P
K
S
S
Site 23
S651
P
S
F
P
E
P
K
S
S
T
Q
A
P
E
S
Site 24
S652
S
F
P
E
P
K
S
S
T
Q
A
P
E
S
Q
Site 25
T653
F
P
E
P
K
S
S
T
Q
A
P
E
S
Q
E
Site 26
S658
S
S
T
Q
A
P
E
S
Q
E
S
Q
E
E
L
Site 27
S661
Q
A
P
E
S
Q
E
S
Q
E
E
L
H
Y
A
Site 28
Y667
E
S
Q
E
E
L
H
Y
A
T
L
N
F
P
G
Site 29
T687
E
A
R
M
P
K
G
T
Q
A
D
Y
A
E
V
Site 30
Y691
P
K
G
T
Q
A
D
Y
A
E
V
K
F
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation