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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNOT6L
Full Name:
CCR4-NOT transcription complex subunit 6-like
Alias:
carbon catabolite repressor 4B; CCR4-NOT transcription complex, 6-like; CCR4-NOT transcription complex, subunit 6-like; CNO6L; DKFZp434K098
Type:
EC 3.1.-.-; Hydrolase
Mass (Da):
63000
Number AA:
UniProt ID:
Q96LI5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004527
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
I
G
M
P
K
E
K
Y
D
P
P
D
P
R
R
Site 2
Y20
P
P
D
P
R
R
I
Y
T
I
M
S
A
E
E
Site 3
T21
P
D
P
R
R
I
Y
T
I
M
S
A
E
E
V
Site 4
S24
R
R
I
Y
T
I
M
S
A
E
E
V
A
N
G
Site 5
S34
E
V
A
N
G
K
K
S
H
W
A
E
L
E
I
Site 6
S42
H
W
A
E
L
E
I
S
G
R
V
R
S
L
S
Site 7
S47
E
I
S
G
R
V
R
S
L
S
T
S
L
W
S
Site 8
S49
S
G
R
V
R
S
L
S
T
S
L
W
S
L
T
Site 9
T50
G
R
V
R
S
L
S
T
S
L
W
S
L
T
H
Site 10
S51
R
V
R
S
L
S
T
S
L
W
S
L
T
H
L
Site 11
Y67
A
L
H
L
N
D
N
Y
L
S
R
I
P
P
D
Site 12
S69
H
L
N
D
N
Y
L
S
R
I
P
P
D
I
A
Site 13
Y83
A
K
L
H
N
L
V
Y
L
D
L
S
S
N
K
Site 14
S87
N
L
V
Y
L
D
L
S
S
N
K
L
R
S
L
Site 15
S88
L
V
Y
L
D
L
S
S
N
K
L
R
S
L
P
Site 16
S93
L
S
S
N
K
L
R
S
L
P
A
E
L
G
N
Site 17
T129
G
R
L
F
Q
L
Q
T
L
G
L
K
G
N
P
Site 18
S138
G
L
K
G
N
P
L
S
Q
D
I
L
N
L
Y
Site 19
Y145
S
Q
D
I
L
N
L
Y
Q
D
P
D
G
T
R
Site 20
Y201
Y
N
V
L
C
D
K
Y
A
T
R
Q
L
Y
G
Site 21
Y207
K
Y
A
T
R
Q
L
Y
G
Y
C
P
S
W
A
Site 22
Y209
A
T
R
Q
L
Y
G
Y
C
P
S
W
A
L
N
Site 23
Y219
S
W
A
L
N
W
E
Y
R
K
K
G
I
M
E
Site 24
S237
N
C
D
A
D
I
I
S
L
Q
E
V
E
T
E
Site 25
Y246
Q
E
V
E
T
E
Q
Y
F
T
L
F
L
P
A
Site 26
Y259
P
A
L
K
E
R
G
Y
D
G
F
F
S
P
K
Site 27
S264
R
G
Y
D
G
F
F
S
P
K
S
R
A
K
I
Site 28
S267
D
G
F
F
S
P
K
S
R
A
K
I
M
S
E
Site 29
S273
K
S
R
A
K
I
M
S
E
Q
E
R
K
H
V
Site 30
S313
A
M
A
N
S
D
G
S
E
A
M
L
N
R
V
Site 31
Y367
H
M
H
W
D
P
E
Y
S
D
V
K
L
I
Q
Site 32
S390
K
N
I
L
E
K
A
S
S
R
P
G
S
P
T
Site 33
S391
N
I
L
E
K
A
S
S
R
P
G
S
P
T
A
Site 34
S395
K
A
S
S
R
P
G
S
P
T
A
D
P
N
S
Site 35
T397
S
S
R
P
G
S
P
T
A
D
P
N
S
I
P
Site 36
S417
D
L
N
S
L
P
D
S
G
V
V
E
Y
L
S
Site 37
Y422
P
D
S
G
V
V
E
Y
L
S
N
G
G
V
A
Site 38
S424
S
G
V
V
E
Y
L
S
N
G
G
V
A
D
N
Site 39
Y440
K
D
F
K
E
L
R
Y
N
E
C
L
M
N
F
Site 40
S455
S
C
N
G
K
N
G
S
S
E
G
R
I
T
H
Site 41
S456
C
N
G
K
N
G
S
S
E
G
R
I
T
H
G
Site 42
T461
G
S
S
E
G
R
I
T
H
G
F
Q
L
K
S
Site 43
Y470
G
F
Q
L
K
S
A
Y
E
N
N
L
M
P
Y
Site 44
Y480
N
L
M
P
Y
T
N
Y
T
F
D
F
K
G
V
Site 45
Y490
D
F
K
G
V
I
D
Y
I
F
Y
S
K
T
H
Site 46
Y493
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Site 47
S494
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
L
Site 48
S527
C
P
H
P
H
I
P
S
D
H
F
S
L
L
T
Site 49
S531
H
I
P
S
D
H
F
S
L
L
T
Q
L
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation