PhosphoNET

           
Protein Info 
   
Short Name:  UBE2E2
Full Name:  Ubiquitin-conjugating enzyme E2 E2
Alias:  FLJ25157; UB2E2; UBCH8; Ubiquitin carrier protein E2; Ubiquitin-conjugating enzyme E2E 2 (UBC4/5); Ubiquitin-protein ligase E2
Type:  Ubiquitin ligase; Ligase; EC 6.3.2.19; Ubiquitin conjugating system
Mass (Da):  22255
Number AA:  201
UniProt ID:  Q96LR5
International Prot ID:  IPI00102173
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0042296  GO:0004842 PhosphoSite+ KinaseNET
Biological Process:  GO:0032020  GO:0019941  GO:0051246 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11EAQRVDDSPSTSGGS
Site 2S13QRVDDSPSTSGGSSD
Site 3T14RVDDSPSTSGGSSDG
Site 4S15VDDSPSTSGGSSDGD
Site 5S19PSTSGGSSDGDQRES
Site 6S26SDGDQRESVQQEPER
Site 7T49EGKISSKTAAKLSTS
Site 8S54SKTAAKLSTSAKRIQ
Site 9T68QKELAEITLDPPPNC
Site 10S76LDPPPNCSAGPKGDN
Site 11Y85GPKGDNIYEWRSTIL
Site 12S89DNIYEWRSTILGPPG
Site 13T90NIYEWRSTILGPPGS
Site 14S111FFLDITFSPDYPFKP
Site 15Y114DITFSPDYPFKPPKV
Site 16T122PFKPPKVTFRTRIYH
Site 17Y128VTFRTRIYHCNINSQ
Site 18S148DILKDNWSPALTISK
Site 19Y181VGSIATQYMTNRAEH
Site 20T183SIATQYMTNRAEHDR
Site 21Y199ARQWTKRYAT_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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