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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAMD8
Full Name:
Sphingomyelin synthase-related protein 1
Alias:
FLJ25082; sphingomyelin synthase-related 1; sterile alpha motif domain containing 8; sterile alpha motif domain-containing 8
Type:
Cell surface
Mass (Da):
48321
Number AA:
415
UniProt ID:
Q96LT4
International Prot ID:
IPI00165639
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006686
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
K
D
E
G
F
F
E
Y
V
D
I
L
C
N
K
Site 2
T43
K
H
R
L
D
G
I
T
L
L
T
L
T
E
Y
Site 3
Y50
T
L
L
T
L
T
E
Y
D
L
R
S
P
P
L
Site 4
S54
L
T
E
Y
D
L
R
S
P
P
L
E
I
K
V
Site 5
S71
D
I
K
R
L
M
L
S
V
R
K
L
Q
K
I
Site 6
Y88
D
V
L
E
E
M
G
Y
N
S
D
S
P
M
G
Site 7
S90
L
E
E
M
G
Y
N
S
D
S
P
M
G
S
M
Site 8
S92
E
M
G
Y
N
S
D
S
P
M
G
S
M
T
P
Site 9
S96
N
S
D
S
P
M
G
S
M
T
P
F
I
S
A
Site 10
S102
G
S
M
T
P
F
I
S
A
L
Q
S
T
D
W
Site 11
Y131
T
D
L
N
S
D
Q
Y
Q
Y
M
N
G
K
N
Site 12
S141
M
N
G
K
N
K
H
S
V
R
R
L
D
P
E
Site 13
Y149
V
R
R
L
D
P
E
Y
W
K
T
I
L
S
C
Site 14
T182
E
R
V
P
D
M
Q
T
Y
P
P
L
P
D
I
Site 15
Y183
R
V
P
D
M
Q
T
Y
P
P
L
P
D
I
F
Site 16
S234
I
L
L
R
R
L
C
S
L
M
G
T
V
F
L
Site 17
T238
R
L
C
S
L
M
G
T
V
F
L
L
R
C
F
Site 18
T262
P
G
Q
H
L
Q
C
T
G
K
I
Y
G
S
V
Site 19
Y266
L
Q
C
T
G
K
I
Y
G
S
V
W
E
K
L
Site 20
Y296
G
V
H
T
C
G
D
Y
M
F
S
G
H
T
V
Site 21
Y315
L
N
F
F
V
T
E
Y
T
P
R
S
W
N
F
Site 22
Y363
T
T
R
L
F
L
Y
Y
H
T
L
A
N
T
R
Site 23
T365
R
L
F
L
Y
Y
H
T
L
A
N
T
R
A
Y
Site 24
Y372
T
L
A
N
T
R
A
Y
Q
Q
S
R
R
A
R
Site 25
Y400
N
G
T
V
P
N
E
Y
C
W
P
F
S
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation