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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C9orf72
Full Name:
Uncharacterized protein C9orf72
Alias:
Type:
Mass (Da):
54328
Number AA:
481
UniProt ID:
Q96LT7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
T
L
C
P
P
P
S
P
A
V
A
K
T
E
Site 2
T15
P
S
P
A
V
A
K
T
E
I
A
L
S
G
K
Site 3
T49
R
H
I
W
A
P
K
T
E
Q
V
L
L
S
D
Site 4
S77
E
I
L
R
N
A
E
S
G
A
I
D
V
K
F
Site 5
S108
G
N
W
N
G
D
R
S
T
Y
G
L
S
I
I
Site 6
T109
N
W
N
G
D
R
S
T
Y
G
L
S
I
I
L
Site 7
Y110
W
N
G
D
R
S
T
Y
G
L
S
I
I
L
P
Site 8
S113
D
R
S
T
Y
G
L
S
I
I
L
P
Q
T
E
Site 9
Y124
P
Q
T
E
L
S
F
Y
L
P
L
H
R
V
C
Site 10
T136
R
V
C
V
D
R
L
T
H
I
I
R
K
G
R
Site 11
S171
R
M
E
D
Q
G
Q
S
I
I
P
M
L
T
G
Site 12
S189
P
V
M
E
L
L
S
S
M
K
S
H
S
V
P
Site 13
S192
E
L
L
S
S
M
K
S
H
S
V
P
E
E
I
Site 14
S194
L
S
S
M
K
S
H
S
V
P
E
E
I
D
I
Site 15
T204
E
E
I
D
I
A
D
T
V
L
N
D
D
D
I
Site 16
S214
N
D
D
D
I
G
D
S
C
H
E
G
F
L
L
Site 17
T256
R
T
L
C
L
F
L
T
P
A
E
R
K
C
S
Site 18
S263
T
P
A
E
R
K
C
S
R
L
C
E
A
E
S
Site 19
S270
S
R
L
C
E
A
E
S
S
F
K
Y
E
S
G
Site 20
S271
R
L
C
E
A
E
S
S
F
K
Y
E
S
G
L
Site 21
Y274
E
A
E
S
S
F
K
Y
E
S
G
L
F
V
Q
Site 22
S290
L
L
K
D
S
T
G
S
F
V
L
P
F
R
Q
Site 23
Y303
R
Q
V
M
Y
A
P
Y
P
T
T
H
I
D
V
Site 24
T314
H
I
D
V
D
V
N
T
V
K
Q
M
P
P
C
Site 25
Y331
H
I
Y
N
Q
R
R
Y
M
R
S
E
L
T
A
Site 26
T343
L
T
A
F
W
R
A
T
S
E
E
D
M
A
Q
Site 27
S344
T
A
F
W
R
A
T
S
E
E
D
M
A
Q
D
Site 28
T352
E
E
D
M
A
Q
D
T
I
I
Y
T
D
E
S
Site 29
T356
A
Q
D
T
I
I
Y
T
D
E
S
F
T
P
D
Site 30
S359
T
I
I
Y
T
D
E
S
F
T
P
D
L
N
I
Site 31
T361
I
Y
T
D
E
S
F
T
P
D
L
N
I
F
Q
Site 32
T375
Q
D
V
L
H
R
D
T
L
V
K
A
F
L
D
Site 33
Y415
K
A
L
T
L
I
K
Y
I
E
D
D
T
Q
K
Site 34
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Site 35
S429
K
G
K
K
P
F
K
S
L
R
N
L
K
I
D
Site 36
T440
L
K
I
D
L
D
L
T
A
E
G
D
L
N
I
Site 37
S461
K
I
K
P
G
L
H
S
F
I
F
G
R
P
F
Site 38
Y469
F
I
F
G
R
P
F
Y
T
S
V
Q
E
R
D
Site 39
S471
F
G
R
P
F
Y
T
S
V
Q
E
R
D
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation