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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INTS4L1
Full Name:
Integrator complex subunit 4-like protein 1
Alias:
Type:
Mass (Da):
48672
Number AA:
439
UniProt ID:
Q96LV5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
P
R
P
A
R
G
C
S
S
A
D
S
S
R
S
Site 2
S19
R
P
A
R
G
C
S
S
A
D
S
S
R
S
S
Site 3
S22
R
G
C
S
S
A
D
S
S
R
S
S
S
A
S
Site 4
S23
G
C
S
S
A
D
S
S
R
S
S
S
A
S
P
Site 5
S25
S
S
A
D
S
S
R
S
S
S
A
S
P
L
A
Site 6
S26
S
A
D
S
S
R
S
S
S
A
S
P
L
A
A
Site 7
S27
A
D
S
S
R
S
S
S
A
S
P
L
A
A
C
Site 8
S29
S
S
R
S
S
S
A
S
P
L
A
A
C
A
G
Site 9
T45
A
P
S
A
L
C
P
T
T
L
P
S
R
R
Y
Site 10
T46
P
S
A
L
C
P
T
T
L
P
S
R
R
Y
G
Site 11
S49
L
C
P
T
T
L
P
S
R
R
Y
G
P
W
N
Site 12
Y52
T
T
L
P
S
R
R
Y
G
P
W
N
I
V
P
Site 13
S104
G
S
M
E
Q
V
S
S
H
F
L
E
Q
T
L
Site 14
T110
S
S
H
F
L
E
Q
T
L
D
K
K
L
M
S
Site 15
S117
T
L
D
K
K
L
M
S
D
L
R
R
K
R
T
Site 16
T124
S
D
L
R
R
K
R
T
A
H
E
R
A
K
E
Site 17
Y133
H
E
R
A
K
E
L
Y
S
S
G
E
F
S
S
Site 18
S134
E
R
A
K
E
L
Y
S
S
G
E
F
S
S
G
Site 19
S135
R
A
K
E
L
Y
S
S
G
E
F
S
S
G
R
Site 20
S139
L
Y
S
S
G
E
F
S
S
G
R
K
W
E
D
Site 21
S140
Y
S
S
G
E
F
S
S
G
R
K
W
E
D
D
Site 22
T155
A
P
K
E
E
V
D
T
G
A
V
N
L
I
E
Site 23
Y178
H
G
L
E
D
E
M
Y
E
V
R
I
A
A
V
Site 24
S197
M
L
A
Q
S
S
P
S
F
A
E
K
C
L
D
Site 25
S221
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Site 26
T224
V
R
L
Q
S
I
H
T
M
R
K
I
S
N
N
Site 27
S229
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Site 28
T233
R
K
I
S
N
N
I
T
L
R
E
D
Q
L
D
Site 29
T241
L
R
E
D
Q
L
D
T
V
L
A
V
L
E
D
Site 30
T284
V
E
L
L
K
N
L
T
K
Y
P
T
D
R
D
Site 31
Y286
L
L
K
N
L
T
K
Y
P
T
D
R
D
S
I
Site 32
T288
K
N
L
T
K
Y
P
T
D
R
D
S
I
W
K
Site 33
T324
S
T
H
P
F
F
D
T
A
E
P
D
M
D
D
Site 34
T350
N
A
A
K
T
C
P
T
M
R
A
L
F
S
D
Site 35
T359
R
A
L
F
S
D
H
T
V
R
H
Y
A
Y
L
Site 36
Y363
S
D
H
T
V
R
H
Y
A
Y
L
R
D
S
L
Site 37
Y365
H
T
V
R
H
Y
A
Y
L
R
D
S
L
S
H
Site 38
S369
H
Y
A
Y
L
R
D
S
L
S
H
L
V
P
A
Site 39
S392
V
S
S
A
V
S
P
S
I
I
P
Q
E
D
P
Site 40
S400
I
I
P
Q
E
D
P
S
Q
Q
L
L
Q
Q
S
Site 41
S407
S
Q
Q
L
L
Q
Q
S
L
E
G
V
C
S
L
Site 42
S413
Q
S
L
E
G
V
C
S
L
Q
H
L
D
P
Q
Site 43
T429
A
Q
E
L
L
E
F
T
I
R
P
C
R
K
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation