KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CCDC111
Full Name:
Coiled-coil domain-containing protein 111
Alias:
Type:
Mass (Da):
64383
Number AA:
560
UniProt ID:
Q96LW4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
K
Q
I
E
E
R
A
S
H
Y
E
R
K
P
L
Site 2
Y19
I
E
E
R
A
S
H
Y
E
R
K
P
L
S
S
Site 3
S25
H
Y
E
R
K
P
L
S
S
V
Y
R
P
R
L
Site 4
S26
Y
E
R
K
P
L
S
S
V
Y
R
P
R
L
S
Site 5
S33
S
V
Y
R
P
R
L
S
K
P
E
E
P
P
S
Site 6
S40
S
K
P
E
E
P
P
S
I
W
R
L
F
H
R
Site 7
Y78
V
G
D
G
Q
R
I
Y
L
V
T
T
Y
A
E
Site 8
Y89
T
Y
A
E
F
W
F
Y
Y
K
S
R
K
N
L
Site 9
Y90
Y
A
E
F
W
F
Y
Y
K
S
R
K
N
L
L
Site 10
Y100
R
K
N
L
L
H
C
Y
E
V
I
P
E
N
A
Site 11
Y112
E
N
A
V
C
K
L
Y
F
D
L
E
F
N
K
Site 12
Y146
C
K
A
L
Q
E
L
Y
G
V
N
C
S
A
E
Site 13
S160
E
D
V
L
N
L
D
S
S
T
D
E
K
F
S
Site 14
S161
D
V
L
N
L
D
S
S
T
D
E
K
F
S
R
Site 15
T162
V
L
N
L
D
S
S
T
D
E
K
F
S
R
H
Site 16
S202
P
A
L
D
L
L
G
S
E
D
D
D
S
A
P
Site 17
S207
L
G
S
E
D
D
D
S
A
P
E
T
T
G
H
Site 18
T211
D
D
D
S
A
P
E
T
T
G
H
G
F
P
H
Site 19
T212
D
D
S
A
P
E
T
T
G
H
G
F
P
H
F
Site 20
S220
G
H
G
F
P
H
F
S
E
A
P
A
R
Q
G
Site 21
S229
A
P
A
R
Q
G
F
S
F
N
K
M
F
T
E
Site 22
S242
T
E
K
A
T
E
E
S
W
T
S
N
S
K
K
Site 23
S245
A
T
E
E
S
W
T
S
N
S
K
K
L
E
R
Site 24
S255
K
K
L
E
R
L
G
S
A
E
Q
S
S
P
D
Site 25
S259
R
L
G
S
A
E
Q
S
S
P
D
L
S
F
L
Site 26
S264
E
Q
S
S
P
D
L
S
F
L
V
V
K
N
N
Site 27
Y284
L
F
V
D
L
G
V
Y
T
R
N
R
N
F
R
Site 28
Y293
R
N
R
N
F
R
L
Y
K
S
S
K
I
G
K
Site 29
S295
R
N
F
R
L
Y
K
S
S
K
I
G
K
R
V
Site 30
S296
N
F
R
L
Y
K
S
S
K
I
G
K
R
V
A
Site 31
S317
N
K
F
F
P
I
Q
S
K
D
V
S
D
E
Y
Site 32
S321
P
I
Q
S
K
D
V
S
D
E
Y
Q
Y
F
L
Site 33
Y324
S
K
D
V
S
D
E
Y
Q
Y
F
L
S
S
L
Site 34
Y326
D
V
S
D
E
Y
Q
Y
F
L
S
S
L
V
S
Site 35
S329
D
E
Y
Q
Y
F
L
S
S
L
V
S
N
V
R
Site 36
S330
E
Y
Q
Y
F
L
S
S
L
V
S
N
V
R
F
Site 37
T340
S
N
V
R
F
S
D
T
L
R
I
L
T
C
E
Site 38
T345
S
D
T
L
R
I
L
T
C
E
P
S
Q
N
K
Site 39
S349
R
I
L
T
C
E
P
S
Q
N
K
Q
K
G
V
Site 40
Y358
N
K
Q
K
G
V
G
Y
F
N
S
I
G
T
S
Site 41
S361
K
G
V
G
Y
F
N
S
I
G
T
S
V
E
T
Site 42
S365
Y
F
N
S
I
G
T
S
V
E
T
I
E
G
F
Site 43
S375
T
I
E
G
F
Q
C
S
P
Y
P
E
V
D
H
Site 44
Y377
E
G
F
Q
C
S
P
Y
P
E
V
D
H
F
V
Site 45
S386
E
V
D
H
F
V
L
S
L
V
N
K
D
G
I
Site 46
Y402
G
G
I
R
R
W
N
Y
F
F
P
E
E
L
L
Site 47
Y411
F
P
E
E
L
L
V
Y
D
I
C
K
Y
R
W
Site 48
S458
C
K
A
E
N
F
K
S
D
C
F
P
L
P
A
Site 49
T481
K
E
E
E
E
F
T
T
D
E
A
D
E
T
R
Site 50
T487
T
T
D
E
A
D
E
T
R
S
N
E
T
Q
N
Site 51
S499
T
Q
N
P
H
K
P
S
P
S
R
L
S
T
G
Site 52
S501
N
P
H
K
P
S
P
S
R
L
S
T
G
A
S
Site 53
S504
K
P
S
P
S
R
L
S
T
G
A
S
A
D
A
Site 54
T505
P
S
P
S
R
L
S
T
G
A
S
A
D
A
V
Site 55
S508
S
R
L
S
T
G
A
S
A
D
A
V
W
D
N
Site 56
Y521
D
N
G
I
D
D
A
Y
F
L
E
A
T
E
D
Site 57
S538
L
A
E
A
A
E
N
S
L
L
S
Y
N
S
E
Site 58
S541
A
A
E
N
S
L
L
S
Y
N
S
E
V
D
E
Site 59
S544
N
S
L
L
S
Y
N
S
E
V
D
E
I
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation