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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AK7
Full Name:
Putative adenylate kinase 7
Alias:
Adenylate kinase 7; EC 2.7.4.3; FLJ32864; KAD7
Type:
Kinase (non-protein), Nucleotide Metabolism group, Purine metabolism family
Mass (Da):
82673
Number AA:
723
UniProt ID:
Q96M32
International Prot ID:
IPI00065250
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004017
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
F
I
N
L
L
D
S
Y
S
S
G
N
I
G
K
Site 2
S29
I
N
L
L
D
S
Y
S
S
G
N
I
G
K
F
Site 3
S45
S
N
C
V
V
G
A
S
L
E
E
I
T
E
E
Site 4
S61
E
E
E
D
E
N
K
S
A
M
L
E
A
S
S
Site 5
T69
A
M
L
E
A
S
S
T
K
V
K
E
G
T
F
Site 6
T75
S
T
K
V
K
E
G
T
F
Q
I
V
G
T
L
Site 7
T81
G
T
F
Q
I
V
G
T
L
S
K
P
D
S
P
Site 8
S83
F
Q
I
V
G
T
L
S
K
P
D
S
P
R
P
Site 9
S87
G
T
L
S
K
P
D
S
P
R
P
D
F
A
V
Site 10
T96
R
P
D
F
A
V
E
T
Y
S
A
I
S
R
E
Site 11
S141
S
A
L
S
E
E
V
S
H
F
E
K
R
K
L
Site 12
S169
K
A
L
D
P
E
D
S
E
V
P
F
T
E
E
Site 13
T174
E
D
S
E
V
P
F
T
E
E
D
Y
R
R
R
Site 14
Y178
V
P
F
T
E
E
D
Y
R
R
R
K
S
H
P
Site 15
S183
E
D
Y
R
R
R
K
S
H
P
N
F
L
D
H
Site 16
Y210
K
A
R
K
F
A
A
Y
V
V
A
A
G
L
Q
Site 17
Y218
V
V
A
A
G
L
Q
Y
G
A
E
G
G
M
L
Site 18
Y274
D
H
V
P
K
P
H
Y
L
V
A
V
D
E
S
Site 19
Y310
K
I
P
R
E
N
A
Y
L
T
K
D
L
T
Q
Site 20
T316
A
Y
L
T
K
D
L
T
Q
D
C
L
D
H
L
Site 21
T354
G
F
V
E
N
I
N
T
I
L
K
E
Y
K
Q
Site 22
Y359
I
N
T
I
L
K
E
Y
K
Q
S
R
G
L
M
Site 23
S382
P
P
A
V
G
K
S
S
I
A
K
E
L
A
K
Site 24
Y390
I
A
K
E
L
A
K
Y
Y
K
L
H
H
I
Q
Site 25
Y391
A
K
E
L
A
K
Y
Y
K
L
H
H
I
Q
L
Site 26
Y459
A
G
Q
L
D
D
Q
Y
I
I
R
F
M
K
E
Site 27
Y478
M
P
C
R
N
Q
G
Y
I
L
D
G
F
P
K
Site 28
T486
I
L
D
G
F
P
K
T
Y
D
Q
A
K
D
L
Site 29
S527
F
V
C
A
L
D
A
S
D
E
F
L
K
E
R
Site 30
Y548
S
I
V
A
G
T
H
Y
S
Q
D
R
F
L
R
Site 31
S549
I
V
A
G
T
H
Y
S
Q
D
R
F
L
R
A
Site 32
S558
D
R
F
L
R
A
L
S
N
Y
R
D
I
N
I
Site 33
Y560
F
L
R
A
L
S
N
Y
R
D
I
N
I
D
D
Site 34
Y573
D
D
E
T
V
F
N
Y
F
D
E
L
E
I
H
Site 35
Y611
E
I
G
E
P
R
N
Y
G
L
T
D
E
E
K
Site 36
T614
E
P
R
N
Y
G
L
T
D
E
E
K
A
E
E
Site 37
S677
R
E
L
L
E
A
Q
S
I
P
L
R
N
Y
L
Site 38
Y683
Q
S
I
P
L
R
N
Y
L
M
T
Y
V
M
P
Site 39
Y714
P
V
D
F
L
A
E
Y
L
F
K
N
N
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation