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Updated November 2019
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Protein Info
Short Name:
CCDC114
Full Name:
Coiled-coil domain-containing protein 114
Alias:
Type:
Mass (Da):
75046
Number AA:
670
UniProt ID:
Q96M63
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
E
G
E
R
R
A
Y
S
K
E
V
H
Q
R
Site 2
S9
E
G
E
R
R
A
Y
S
K
E
V
H
Q
R
I
Site 3
S50
Q
V
K
R
L
R
D
S
Q
R
L
E
N
M
D
Site 4
T93
E
W
E
T
R
I
F
T
H
S
K
N
V
R
S
Site 5
S95
E
T
R
I
F
T
H
S
K
N
V
R
S
P
G
Site 6
S100
T
H
S
K
N
V
R
S
P
G
F
I
L
D
Q
Site 7
Y153
L
R
I
D
R
N
R
Y
L
N
V
D
R
K
L
Site 8
Y182
I
L
S
S
T
S
A
Y
A
V
R
E
E
A
K
Site 9
S206
A
E
K
E
E
A
Q
S
E
M
E
A
Q
V
L
Site 10
S259
A
E
G
V
W
K
T
S
Q
E
R
L
V
L
C
Site 11
Y267
Q
E
R
L
V
L
C
Y
E
D
A
L
N
K
L
Site 12
S275
E
D
A
L
N
K
L
S
Q
L
M
G
E
S
D
Site 13
S281
L
S
Q
L
M
G
E
S
D
P
D
L
L
V
Q
Site 14
Y290
P
D
L
L
V
Q
K
Y
L
E
I
E
E
R
N
Site 15
S327
E
M
Q
E
A
L
V
S
A
R
A
S
K
D
D
Site 16
S331
A
L
V
S
A
R
A
S
K
D
D
Q
H
L
L
Site 17
S355
Q
R
M
D
K
V
H
S
E
A
E
R
L
E
A
Site 18
S401
D
L
L
G
V
K
T
S
M
G
D
R
D
M
G
Site 19
T463
A
P
L
Q
P
P
D
T
L
E
D
P
P
G
F
Site 20
S473
D
P
P
G
F
E
A
S
D
D
Y
P
M
S
R
Site 21
Y476
G
F
E
A
S
D
D
Y
P
M
S
R
E
E
L
Site 22
S479
A
S
D
D
Y
P
M
S
R
E
E
L
L
S
Q
Site 23
S485
M
S
R
E
E
L
L
S
Q
V
E
K
L
V
E
Site 24
S517
A
K
L
D
G
T
L
S
V
D
L
A
S
T
Q
Site 25
S522
T
L
S
V
D
L
A
S
T
Q
R
A
G
S
S
Site 26
T523
L
S
V
D
L
A
S
T
Q
R
A
G
S
S
T
Site 27
S528
A
S
T
Q
R
A
G
S
S
T
V
L
V
P
T
Site 28
T530
T
Q
R
A
G
S
S
T
V
L
V
P
T
R
H
Site 29
T535
S
S
T
V
L
V
P
T
R
H
P
H
A
I
P
Site 30
S544
H
P
H
A
I
P
G
S
I
L
S
H
K
T
S
Site 31
S547
A
I
P
G
S
I
L
S
H
K
T
S
R
D
R
Site 32
T550
G
S
I
L
S
H
K
T
S
R
D
R
G
S
L
Site 33
S551
S
I
L
S
H
K
T
S
R
D
R
G
S
L
G
Site 34
S556
K
T
S
R
D
R
G
S
L
G
H
V
T
F
G
Site 35
T561
R
G
S
L
G
H
V
T
F
G
G
L
S
S
S
Site 36
S566
H
V
T
F
G
G
L
S
S
S
T
G
H
L
P
Site 37
S568
T
F
G
G
L
S
S
S
T
G
H
L
P
S
H
Site 38
S574
S
S
T
G
H
L
P
S
H
I
T
H
G
D
P
Site 39
T583
I
T
H
G
D
P
N
T
G
H
V
T
F
G
S
Site 40
T587
D
P
N
T
G
H
V
T
F
G
S
T
S
A
S
Site 41
S590
T
G
H
V
T
F
G
S
T
S
A
S
S
G
G
Site 42
T591
G
H
V
T
F
G
S
T
S
A
S
S
G
G
H
Site 43
S592
H
V
T
F
G
S
T
S
A
S
S
G
G
H
V
Site 44
S594
T
F
G
S
T
S
A
S
S
G
G
H
V
T
F
Site 45
S595
F
G
S
T
S
A
S
S
G
G
H
V
T
F
R
Site 46
T600
A
S
S
G
G
H
V
T
F
R
P
V
S
A
S
Site 47
S605
H
V
T
F
R
P
V
S
A
S
S
Y
L
G
S
Site 48
S607
T
F
R
P
V
S
A
S
S
Y
L
G
S
T
G
Site 49
S608
F
R
P
V
S
A
S
S
Y
L
G
S
T
G
Y
Site 50
Y609
R
P
V
S
A
S
S
Y
L
G
S
T
G
Y
V
Site 51
S612
S
A
S
S
Y
L
G
S
T
G
Y
V
G
S
S
Site 52
T613
A
S
S
Y
L
G
S
T
G
Y
V
G
S
S
R
Site 53
Y615
S
Y
L
G
S
T
G
Y
V
G
S
S
R
G
G
Site 54
S618
G
S
T
G
Y
V
G
S
S
R
G
G
E
N
T
Site 55
T625
S
S
R
G
G
E
N
T
E
G
G
V
E
S
G
Site 56
T634
G
G
V
E
S
G
G
T
A
S
D
S
S
G
G
Site 57
S636
V
E
S
G
G
T
A
S
D
S
S
G
G
L
G
Site 58
S638
S
G
G
T
A
S
D
S
S
G
G
L
G
S
S
Site 59
S639
G
G
T
A
S
D
S
S
G
G
L
G
S
S
R
Site 60
S644
D
S
S
G
G
L
G
S
S
R
D
H
V
S
S
Site 61
S645
S
S
G
G
L
G
S
S
R
D
H
V
S
S
T
Site 62
S650
G
S
S
R
D
H
V
S
S
T
G
P
A
S
S
Site 63
S651
S
S
R
D
H
V
S
S
T
G
P
A
S
S
T
Site 64
T652
S
R
D
H
V
S
S
T
G
P
A
S
S
T
G
Site 65
S656
V
S
S
T
G
P
A
S
S
T
G
P
G
S
S
Site 66
S657
S
S
T
G
P
A
S
S
T
G
P
G
S
S
T
Site 67
T658
S
T
G
P
A
S
S
T
G
P
G
S
S
T
S
Site 68
S662
A
S
S
T
G
P
G
S
S
T
S
K
D
S
R
Site 69
S663
S
S
T
G
P
G
S
S
T
S
K
D
S
R
G
Site 70
T664
S
T
G
P
G
S
S
T
S
K
D
S
R
G
_
Site 71
S665
T
G
P
G
S
S
T
S
K
D
S
R
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation