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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C12orf66
Full Name:
UPF0536 protein C12orf66
Alias:
Type:
Mass (Da):
50415
Number AA:
445
UniProt ID:
Q96MD2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y30
S
H
L
G
I
F
S
Y
D
K
A
K
D
N
V
Site 2
S46
K
E
R
E
A
N
K
S
A
G
G
S
W
L
S
Site 3
S53
S
A
G
G
S
W
L
S
L
L
A
A
L
A
H
Site 4
Y73
K
V
Y
H
S
L
T
Y
L
G
Q
K
L
G
G
Site 5
S82
G
Q
K
L
G
G
Q
S
F
F
S
R
K
D
S
Site 6
S85
L
G
G
Q
S
F
F
S
R
K
D
S
I
R
T
Site 7
S89
S
F
F
S
R
K
D
S
I
R
T
I
Y
T
S
Site 8
T92
S
R
K
D
S
I
R
T
I
Y
T
S
L
H
N
Site 9
Y94
K
D
S
I
R
T
I
Y
T
S
L
H
N
E
L
Site 10
S96
S
I
R
T
I
Y
T
S
L
H
N
E
L
K
K
Site 11
T106
N
E
L
K
K
V
V
T
G
R
G
A
L
G
G
Site 12
S123
P
H
V
E
E
L
L
S
H
L
S
E
Q
L
C
Site 13
Y143
R
M
E
I
A
D
F
Y
E
K
M
Y
T
L
S
Site 14
T148
D
F
Y
E
K
M
Y
T
L
S
T
Q
K
F
I
Site 15
Y171
L
D
A
I
M
K
K
Y
S
S
R
F
H
H
P
Site 16
S181
R
F
H
H
P
I
L
S
P
L
E
S
S
F
Q
Site 17
S205
L
K
A
Q
A
Q
V
S
E
W
K
F
L
P
S
Site 18
S212
S
E
W
K
F
L
P
S
L
V
N
L
H
S
A
Site 19
S218
P
S
L
V
N
L
H
S
A
H
T
K
L
Q
T
Site 20
T236
I
F
E
K
Q
R
E
T
K
K
H
L
F
G
G
Site 21
S245
K
H
L
F
G
G
Q
S
Q
K
A
V
Q
P
P
Site 22
T281
H
E
A
L
S
R
Q
T
T
A
S
E
M
K
T
Site 23
T282
E
A
L
S
R
Q
T
T
A
S
E
M
K
T
L
Site 24
S284
L
S
R
Q
T
T
A
S
E
M
K
T
L
T
A
Site 25
T288
T
T
A
S
E
M
K
T
L
T
A
K
A
N
P
Site 26
S302
P
D
F
F
G
K
I
S
S
F
I
R
K
Y
D
Site 27
S303
D
F
F
G
K
I
S
S
F
I
R
K
Y
D
A
Site 28
S322
L
I
F
D
N
R
G
S
E
S
F
Q
G
H
G
Site 29
Y330
E
S
F
Q
G
H
G
Y
H
H
P
H
S
Y
R
Site 30
S335
H
G
Y
H
H
P
H
S
Y
R
E
A
P
K
G
Site 31
S354
P
A
V
V
S
L
P
S
D
R
P
V
M
H
W
Site 32
T369
P
N
V
I
M
I
M
T
D
R
T
S
D
L
N
Site 33
S373
M
I
M
T
D
R
T
S
D
L
N
S
L
E
K
Site 34
S377
D
R
T
S
D
L
N
S
L
E
K
V
V
H
F
Site 35
Y393
D
D
K
V
Q
S
T
Y
F
L
T
R
P
E
P
Site 36
S413
I
I
F
E
S
K
K
S
E
R
D
S
H
F
I
Site 37
S417
S
K
K
S
E
R
D
S
H
F
I
S
F
L
N
Site 38
S421
E
R
D
S
H
F
I
S
F
L
N
E
V
S
L
Site 39
S438
K
N
P
K
V
F
A
S
L
K
P
G
S
K
G
Site 40
S443
F
A
S
L
K
P
G
S
K
G
S
C
Y
Q
C
Site 41
Y448
P
G
S
K
G
S
C
Y
Q
C
N
Y
F
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation