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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL18
Full Name:
F-box/LRR-repeat protein 18
Alias:
F-box and leucine-rich repeat protein 18
Type:
Mass (Da):
88341
Number AA:
805
UniProt ID:
Q96ME1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
S
S
G
E
D
I
S
N
D
D
D
D
M
H
Site 2
T71
L
D
K
S
L
I
H
T
V
L
L
Q
K
D
Y
Site 3
Y78
T
V
L
L
Q
K
D
Y
Q
A
S
E
D
K
V
Site 4
S120
E
H
V
A
R
C
R
S
L
V
K
V
N
L
S
Site 5
T132
N
L
S
G
C
H
L
T
S
L
R
L
S
K
M
Site 6
S141
L
R
L
S
K
M
L
S
A
L
Q
H
L
R
S
Site 7
S154
R
S
L
A
I
D
V
S
P
G
F
D
A
S
Q
Site 8
S160
V
S
P
G
F
D
A
S
Q
L
S
S
E
C
K
Site 9
S163
G
F
D
A
S
Q
L
S
S
E
C
K
A
T
L
Site 10
S164
F
D
A
S
Q
L
S
S
E
C
K
A
T
L
S
Site 11
T169
L
S
S
E
C
K
A
T
L
S
R
V
R
E
L
Site 12
S171
S
E
C
K
A
T
L
S
R
V
R
E
L
K
Q
Site 13
T179
R
V
R
E
L
K
Q
T
L
F
T
P
S
Y
G
Site 14
T182
E
L
K
Q
T
L
F
T
P
S
Y
G
V
V
P
Site 15
Y227
G
Q
S
N
V
P
H
Y
Q
N
L
R
V
F
Y
Site 16
Y234
Y
Q
N
L
R
V
F
Y
A
R
L
A
P
G
Y
Site 17
Y241
Y
A
R
L
A
P
G
Y
I
N
Q
E
V
V
R
Site 18
Y250
N
Q
E
V
V
R
L
Y
L
A
V
L
S
D
R
Site 19
S255
R
L
Y
L
A
V
L
S
D
R
T
P
Q
N
L
Site 20
T258
L
A
V
L
S
D
R
T
P
Q
N
L
H
A
F
Site 21
T279
S
F
A
E
S
G
A
T
K
N
L
L
D
S
M
Site 22
S285
A
T
K
N
L
L
D
S
M
A
R
N
V
V
L
Site 23
S300
D
A
L
Q
L
P
K
S
W
L
N
G
S
S
L
Site 24
S306
K
S
W
L
N
G
S
S
L
L
Q
H
M
K
F
Site 25
Y318
M
K
F
N
N
P
F
Y
F
S
F
S
R
C
T
Site 26
S322
N
P
F
Y
F
S
F
S
R
C
T
L
S
G
G
Site 27
S327
S
F
S
R
C
T
L
S
G
G
H
L
I
Q
Q
Site 28
S344
N
G
G
K
D
L
R
S
L
A
S
L
N
L
S
Site 29
S358
S
G
C
V
H
C
L
S
P
D
S
L
L
R
K
Site 30
S361
V
H
C
L
S
P
D
S
L
L
R
K
A
E
D
Site 31
S372
K
A
E
D
D
I
D
S
S
I
L
E
T
L
V
Site 32
S391
N
L
R
H
L
N
L
S
A
A
H
H
H
S
S
Site 33
S397
L
S
A
A
H
H
H
S
S
E
G
L
G
R
H
Site 34
S398
S
A
A
H
H
H
S
S
E
G
L
G
R
H
L
Site 35
S428
P
V
C
S
V
A
D
S
A
P
R
A
D
R
A
Site 36
S458
K
V
R
V
G
V
Q
S
C
P
S
P
F
S
G
Site 37
S464
Q
S
C
P
S
P
F
S
G
Q
A
C
P
Q
P
Site 38
S473
Q
A
C
P
Q
P
S
S
V
F
W
S
L
L
K
Site 39
S493
E
H
L
E
L
I
G
S
N
F
S
S
A
M
P
Site 40
S497
L
I
G
S
N
F
S
S
A
M
P
R
N
E
P
Site 41
S509
N
E
P
A
I
R
N
S
L
P
P
C
S
R
A
Site 42
S514
R
N
S
L
P
P
C
S
R
A
Q
S
V
G
D
Site 43
S518
P
P
C
S
R
A
Q
S
V
G
D
S
E
V
A
Site 44
S522
R
A
Q
S
V
G
D
S
E
V
A
A
I
G
Q
Site 45
Y599
D
L
R
L
E
Q
P
Y
F
S
A
N
A
Q
F
Site 46
S611
A
Q
F
F
Q
A
L
S
Q
C
P
S
L
Q
R
Site 47
S623
L
Q
R
L
C
L
V
S
R
S
G
T
L
Q
P
Site 48
S625
R
L
C
L
V
S
R
S
G
T
L
Q
P
D
A
Site 49
T656
F
T
G
E
S
L
A
T
C
K
S
L
Q
Q
S
Site 50
S659
E
S
L
A
T
C
K
S
L
Q
Q
S
L
L
R
Site 51
S663
T
C
K
S
L
Q
Q
S
L
L
R
R
W
G
E
Site 52
T672
L
R
R
W
G
E
V
T
G
R
R
P
Q
L
F
Site 53
T680
G
R
R
P
Q
L
F
T
E
L
R
E
E
P
S
Site 54
S687
T
E
L
R
E
E
P
S
A
R
T
S
R
A
T
Site 55
S691
E
E
P
S
A
R
T
S
R
A
T
G
R
R
Q
Site 56
T694
S
A
R
T
S
R
A
T
G
R
R
Q
P
C
L
Site 57
S762
L
F
E
T
E
S
H
S
V
V
Q
A
G
V
Q
Site 58
S774
G
V
Q
W
R
D
L
S
S
L
Q
P
L
L
S
Site 59
S775
V
Q
W
R
D
L
S
S
L
Q
P
L
L
S
G
Site 60
S781
S
S
L
Q
P
L
L
S
G
L
Q
P
Q
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation