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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NSMCE2
Full Name:
E3 SUMO-protein ligase NSE2
Alias:
Non-structural maintenance of chromosomes element 2 homologue
Type:
Mass (Da):
27914
Number AA:
247
UniProt ID:
Q96MF7
International Prot ID:
IPI00166784
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
P
G
R
S
S
S
N
S
G
S
T
Site 2
S6
_
_
M
P
G
R
S
S
S
N
S
G
S
T
G
Site 3
S7
_
M
P
G
R
S
S
S
N
S
G
S
T
G
F
Site 4
S9
P
G
R
S
S
S
N
S
G
S
T
G
F
I
S
Site 5
S11
R
S
S
S
N
S
G
S
T
G
F
I
S
F
S
Site 6
T12
S
S
S
N
S
G
S
T
G
F
I
S
F
S
G
Site 7
S25
S
G
V
E
S
A
L
S
S
L
K
N
F
Q
A
Site 8
S36
N
F
Q
A
C
I
N
S
G
M
D
T
A
S
S
Site 9
S51
V
A
L
D
L
V
E
S
Q
T
E
V
S
S
E
Site 10
T53
L
D
L
V
E
S
Q
T
E
V
S
S
E
Y
S
Site 11
S57
E
S
Q
T
E
V
S
S
E
Y
S
M
D
K
A
Site 12
S60
T
E
V
S
S
E
Y
S
M
D
K
A
M
V
E
Site 13
T70
K
A
M
V
E
F
A
T
L
D
R
Q
L
N
H
Site 14
Y78
L
D
R
Q
L
N
H
Y
V
K
A
V
Q
S
T
Site 15
S116
L
A
L
Q
S
K
N
S
D
A
D
F
Q
N
N
Site 16
T151
A
D
R
E
A
D
G
T
E
G
V
D
E
D
I
Site 17
Y189
N
K
V
C
G
H
T
Y
E
E
D
A
I
V
R
Site 18
S200
A
I
V
R
M
I
E
S
R
Q
K
R
K
K
K
Site 19
Y209
Q
K
R
K
K
K
A
Y
C
P
Q
I
G
C
S
Site 20
T218
P
Q
I
G
C
S
H
T
D
I
R
K
S
D
L
Site 21
S223
S
H
T
D
I
R
K
S
D
L
I
Q
D
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation