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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HEXIM2
Full Name:
Protein HEXIM2
Alias:
Hexamethylene bis-acetamide-inducible protein 2
Type:
Transcription, coactivator/corepressor
Mass (Da):
32419
Number AA:
286
UniProt ID:
Q96MH2
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004861
GO:0005515
GO:0017069
PhosphoSite+
KinaseNET
Biological Process:
GO:0045736
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
Q
T
A
C
N
A
E
S
P
V
A
L
E
E
A
Site 2
T23
V
A
L
E
E
A
K
T
S
G
A
P
G
S
P
Site 3
S24
A
L
E
E
A
K
T
S
G
A
P
G
S
P
Q
Site 4
S29
K
T
S
G
A
P
G
S
P
Q
T
P
P
E
R
Site 5
T32
G
A
P
G
S
P
Q
T
P
P
E
R
H
D
S
Site 6
S39
T
P
P
E
R
H
D
S
G
G
S
L
P
L
T
Site 7
S42
E
R
H
D
S
G
G
S
L
P
L
T
P
R
M
Site 8
T46
S
G
G
S
L
P
L
T
P
R
M
E
S
H
S
Site 9
S51
P
L
T
P
R
M
E
S
H
S
E
D
E
D
L
Site 10
S53
T
P
R
M
E
S
H
S
E
D
E
D
L
A
G
Site 11
S69
V
G
G
L
G
W
N
S
R
S
P
R
T
Q
S
Site 12
S71
G
L
G
W
N
S
R
S
P
R
T
Q
S
P
G
Site 13
T74
W
N
S
R
S
P
R
T
Q
S
P
G
G
C
S
Site 14
S76
S
R
S
P
R
T
Q
S
P
G
G
C
S
A
E
Site 15
S81
T
Q
S
P
G
G
C
S
A
E
A
V
L
A
R
Site 16
S96
K
K
H
R
R
R
P
S
K
R
K
R
H
W
R
Site 17
Y105
R
K
R
H
W
R
P
Y
L
E
L
S
W
A
E
Site 18
S109
W
R
P
Y
L
E
L
S
W
A
E
K
Q
Q
R
Site 19
S121
Q
Q
R
D
E
R
Q
S
Q
R
A
S
R
V
R
Site 20
S125
E
R
Q
S
Q
R
A
S
R
V
R
E
E
M
F
Site 21
Y141
K
G
Q
P
V
A
P
Y
N
T
T
Q
F
L
M
Site 22
S165
L
D
V
P
H
G
I
S
H
P
G
S
S
G
E
Site 23
S169
H
G
I
S
H
P
G
S
S
G
E
S
E
A
G
Site 24
S170
G
I
S
H
P
G
S
S
G
E
S
E
A
G
D
Site 25
S173
H
P
G
S
S
G
E
S
E
A
G
D
S
D
G
Site 26
S178
G
E
S
E
A
G
D
S
D
G
R
G
R
A
H
Site 27
S194
E
F
Q
R
K
D
F
S
E
T
Y
E
R
F
H
Site 28
Y197
R
K
D
F
S
E
T
Y
E
R
F
H
T
E
S
Site 29
T202
E
T
Y
E
R
F
H
T
E
S
L
Q
G
R
S
Site 30
S204
Y
E
R
F
H
T
E
S
L
Q
G
R
S
K
Q
Site 31
Y217
K
Q
E
L
V
R
D
Y
L
E
L
E
K
R
L
Site 32
S225
L
E
L
E
K
R
L
S
Q
A
E
E
E
T
R
Site 33
S245
Q
A
C
T
G
Q
Q
S
C
R
Q
V
E
E
L
Site 34
T261
A
E
V
Q
R
L
R
T
E
N
Q
R
L
R
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation