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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPA12B
Full Name:
Heat shock 70 kDa protein 12B
Alias:
C20orf60; dJ1009E24.2; heat shock 70kD protein 12B; HS12B
Type:
Mass (Da):
75688
Number AA:
686
UniProt ID:
Q96MM6
International Prot ID:
IPI00307820
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
E
M
G
L
Q
G
L
Y
I
G
S
S
P
E
R
Site 2
S16
L
Q
G
L
Y
I
G
S
S
P
E
R
S
P
V
Site 3
S17
Q
G
L
Y
I
G
S
S
P
E
R
S
P
V
P
Site 4
S21
I
G
S
S
P
E
R
S
P
V
P
S
P
P
G
Site 5
S25
P
E
R
S
P
V
P
S
P
P
G
S
P
R
T
Site 6
S29
P
V
P
S
P
P
G
S
P
R
T
Q
E
S
C
Site 7
T32
S
P
P
G
S
P
R
T
Q
E
S
C
G
I
A
Site 8
S35
G
S
P
R
T
Q
E
S
C
G
I
A
P
L
T
Site 9
T42
S
C
G
I
A
P
L
T
P
S
Q
S
P
K
P
Site 10
S44
G
I
A
P
L
T
P
S
Q
S
P
K
P
E
V
Site 11
S46
A
P
L
T
P
S
Q
S
P
K
P
E
V
R
A
Site 12
Y74
F
G
T
T
S
S
G
Y
A
F
S
F
A
S
D
Site 13
S77
T
S
S
G
Y
A
F
S
F
A
S
D
P
E
A
Site 14
S117
T
P
E
G
A
F
H
S
F
G
Y
T
A
R
D
Site 15
T121
A
F
H
S
F
G
Y
T
A
R
D
Y
Y
H
D
Site 16
Y125
F
G
Y
T
A
R
D
Y
Y
H
D
L
D
P
E
Site 17
Y126
G
Y
T
A
R
D
Y
Y
H
D
L
D
P
E
E
Site 18
Y139
E
E
A
R
D
W
L
Y
F
E
K
F
K
M
K
Site 19
S149
K
F
K
M
K
I
H
S
A
T
D
L
T
L
K
Site 20
T154
I
H
S
A
T
D
L
T
L
K
T
Q
L
E
A
Site 21
S192
L
Q
E
L
R
E
Q
S
P
S
L
P
E
K
D
Site 22
S194
E
L
R
E
Q
S
P
S
L
P
E
K
D
T
V
Site 23
T200
P
S
L
P
E
K
D
T
V
R
W
V
L
T
V
Site 24
Y249
E
P
E
A
A
S
V
Y
C
R
K
L
R
L
H
Site 25
S262
L
H
Q
L
L
D
L
S
G
R
A
P
G
G
G
Site 26
S276
G
R
L
G
E
R
R
S
I
D
S
S
F
R
Q
Site 27
S279
G
E
R
R
S
I
D
S
S
F
R
Q
A
R
E
Site 28
S280
E
R
R
S
I
D
S
S
F
R
Q
A
R
E
Q
Site 29
S291
A
R
E
Q
L
R
R
S
R
H
S
R
T
F
L
Site 30
S294
Q
L
R
R
S
R
H
S
R
T
F
L
V
E
S
Site 31
T296
R
R
S
R
H
S
R
T
F
L
V
E
S
G
V
Site 32
Y316
E
M
Q
A
G
D
R
Y
V
V
A
D
C
G
G
Site 33
T329
G
G
G
T
V
D
L
T
V
H
Q
L
E
Q
P
Site 34
Y344
H
G
T
L
K
E
L
Y
K
A
S
G
G
P
Y
Site 35
T375
F
G
E
D
F
I
A
T
F
K
R
Q
R
P
A
Site 36
T397
A
F
E
A
R
K
R
T
A
G
P
H
R
A
G
Site 37
Y418
P
F
S
F
I
D
F
Y
R
K
Q
R
G
H
N
Site 38
T428
Q
R
G
H
N
V
E
T
A
L
R
R
S
S
V
Site 39
S433
V
E
T
A
L
R
R
S
S
V
N
F
V
K
W
Site 40
S434
E
T
A
L
R
R
S
S
V
N
F
V
K
W
S
Site 41
S442
V
N
F
V
K
W
S
S
Q
G
M
L
R
M
S
Site 42
S449
S
Q
G
M
L
R
M
S
C
E
A
M
N
E
L
Site 43
T542
R
V
R
R
S
P
L
T
Y
G
V
G
V
L
N
Site 44
Y543
V
R
R
S
P
L
T
Y
G
V
G
V
L
N
R
Site 45
S593
L
G
E
E
V
R
R
S
Y
C
P
A
R
P
G
Site 46
Y594
G
E
E
V
R
R
S
Y
C
P
A
R
P
G
Q
Site 47
T620
A
E
D
A
R
F
I
T
D
P
G
V
R
K
C
Site 48
S631
V
R
K
C
G
A
L
S
L
E
L
E
P
A
D
Site 49
T643
P
A
D
C
G
Q
D
T
A
G
A
P
P
G
R
Site 50
T667
G
D
T
E
I
K
V
T
A
V
D
V
S
T
N
Site 51
S672
K
V
T
A
V
D
V
S
T
N
R
S
V
R
A
Site 52
T673
V
T
A
V
D
V
S
T
N
R
S
V
R
A
S
Site 53
S676
V
D
V
S
T
N
R
S
V
R
A
S
I
D
F
Site 54
S680
T
N
R
S
V
R
A
S
I
D
F
L
S
N
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation