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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HS6ST2
Full Name:
Heparan-sulfate 6-O-sulfotransferase 2
Alias:
Type:
Mass (Da):
69130
Number AA:
605
UniProt ID:
Q96MM7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
E
R
G
A
P
V
R
T
T
C
P
R
R
H
S
Site 2
T26
R
G
A
P
V
R
T
T
C
P
R
R
H
S
R
Site 3
S32
T
T
C
P
R
R
H
S
R
V
E
A
E
L
A
Site 4
S49
R
P
G
S
V
A
A
S
V
R
A
G
P
P
R
Site 5
S59
A
G
P
P
R
G
V
S
H
G
F
H
T
R
P
Site 6
S75
L
D
K
P
R
K
A
S
S
S
L
A
G
A
A
Site 7
S76
D
K
P
R
K
A
S
S
S
L
A
G
A
A
C
Site 8
S77
K
P
R
K
A
S
S
S
L
A
G
A
A
C
A
Site 9
S91
A
P
L
F
A
L
L
S
R
G
R
R
R
R
M
Site 10
S109
R
R
R
W
D
L
G
S
L
C
R
A
L
L
T
Site 11
S135
H
V
L
G
A
I
F
S
K
I
F
G
P
M
A
Site 12
S143
K
I
F
G
P
M
A
S
V
G
N
M
D
E
K
Site 13
S151
V
G
N
M
D
E
K
S
N
K
L
L
L
A
L
Site 14
S187
L
L
R
L
Q
A
F
S
S
P
V
P
D
P
Y
Site 15
S188
L
R
L
Q
A
F
S
S
P
V
P
D
P
Y
R
Site 16
Y194
S
S
P
V
P
D
P
Y
R
S
E
D
E
S
S
Site 17
S196
P
V
P
D
P
Y
R
S
E
D
E
S
S
A
R
Site 18
S200
P
Y
R
S
E
D
E
S
S
A
R
F
V
P
R
Site 19
S201
Y
R
S
E
D
E
S
S
A
R
F
V
P
R
Y
Site 20
Y208
S
A
R
F
V
P
R
Y
N
F
T
R
G
D
L
Site 21
T237
V
F
L
H
I
Q
K
T
G
G
T
T
F
G
R
Site 22
T241
I
Q
K
T
G
G
T
T
F
G
R
H
L
V
R
Site 23
T266
R
V
G
Q
K
K
C
T
C
H
R
P
G
K
R
Site 24
T275
H
R
P
G
K
R
E
T
W
L
F
S
R
F
S
Site 25
S279
K
R
E
T
W
L
F
S
R
F
S
T
G
W
S
Site 26
S302
E
L
T
S
C
V
P
S
V
V
D
G
K
R
D
Site 27
S315
R
D
A
R
L
R
P
S
R
N
F
H
Y
I
T
Site 28
S329
T
I
L
R
D
P
V
S
R
Y
L
S
E
W
R
Site 29
Y331
L
R
D
P
V
S
R
Y
L
S
E
W
R
H
V
Site 30
S333
D
P
V
S
R
Y
L
S
E
W
R
H
V
Q
R
Site 31
T343
R
H
V
Q
R
G
A
T
W
K
A
S
L
H
V
Site 32
S347
R
G
A
T
W
K
A
S
L
H
V
C
D
G
R
Site 33
T357
V
C
D
G
R
P
P
T
S
E
E
L
P
S
C
Site 34
S358
C
D
G
R
P
P
T
S
E
E
L
P
S
C
Y
Site 35
S363
P
T
S
E
E
L
P
S
C
Y
T
G
D
D
W
Site 36
Y365
S
E
E
L
P
S
C
Y
T
G
D
D
W
S
G
Site 37
Y383
K
E
F
M
D
C
P
Y
N
L
A
N
N
R
Q
Site 38
T398
V
R
M
L
S
D
L
T
L
V
G
C
Y
N
L
Site 39
S406
L
V
G
C
Y
N
L
S
V
M
P
E
K
Q
R
Site 40
T440
L
T
E
F
Q
R
K
T
Q
Y
L
F
E
K
T
Site 41
Y442
E
F
Q
R
K
T
Q
Y
L
F
E
K
T
F
N
Site 42
T461
S
P
F
T
Q
Y
N
T
T
R
A
S
S
V
E
Site 43
S465
Q
Y
N
T
T
R
A
S
S
V
E
I
N
E
E
Site 44
S466
Y
N
T
T
R
A
S
S
V
E
I
N
E
E
I
Site 45
Y488
N
F
L
D
M
E
L
Y
S
Y
A
K
D
L
F
Site 46
Y490
L
D
M
E
L
Y
S
Y
A
K
D
L
F
L
Q
Site 47
Y499
K
D
L
F
L
Q
R
Y
Q
F
M
R
Q
K
E
Site 48
T528
L
K
G
R
L
L
Q
T
H
F
Q
S
Q
G
Q
Site 49
S532
L
L
Q
T
H
F
Q
S
Q
G
Q
G
Q
S
Q
Site 50
S538
Q
S
Q
G
Q
G
Q
S
Q
N
P
N
Q
N
Q
Site 51
S546
Q
N
P
N
Q
N
Q
S
Q
N
P
N
P
N
A
Site 52
T566
Q
N
L
M
Q
N
L
T
Q
S
L
S
Q
K
E
Site 53
S568
L
M
Q
N
L
T
Q
S
L
S
Q
K
E
N
R
Site 54
S570
Q
N
L
T
Q
S
L
S
Q
K
E
N
R
E
S
Site 55
S577
S
Q
K
E
N
R
E
S
P
K
Q
N
S
G
K
Site 56
T590
G
K
E
Q
N
D
N
T
S
N
G
T
N
D
Y
Site 57
S591
K
E
Q
N
D
N
T
S
N
G
T
N
D
Y
I
Site 58
T594
N
D
N
T
S
N
G
T
N
D
Y
I
G
S
V
Site 59
Y597
T
S
N
G
T
N
D
Y
I
G
S
V
E
K
W
Site 60
S600
G
T
N
D
Y
I
G
S
V
E
K
W
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation