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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF778
Full Name:
Zinc finger protein 778
Alias:
FLJ31875; Zn778; Znf778; Znf778 protein
Type:
Mass (Da):
77510
Number AA:
UniProt ID:
Q96MU6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T45
L
Q
E
W
R
L
K
T
K
G
P
A
L
R
Q
Site 2
S55
P
A
L
R
Q
D
R
S
W
F
R
A
S
N
E
Site 3
S60
D
R
S
W
F
R
A
S
N
E
T
Q
T
A
R
Site 4
T63
W
F
R
A
S
N
E
T
Q
T
A
R
S
H
N
Site 5
T65
R
A
S
N
E
T
Q
T
A
R
S
H
N
G
G
Site 6
T78
G
G
Q
L
C
D
R
T
Q
C
G
E
A
F
S
Site 7
S85
T
Q
C
G
E
A
F
S
E
H
S
G
L
S
T
Site 8
S91
F
S
E
H
S
G
L
S
T
H
V
R
T
Q
N
Site 9
T92
S
E
H
S
G
L
S
T
H
V
R
T
Q
N
T
Site 10
Y108
D
S
C
V
S
N
H
Y
E
R
D
F
F
I
P
Site 11
S128
F
K
I
G
E
Q
F
S
V
L
G
Q
C
G
K
Site 12
S138
G
Q
C
G
K
A
F
S
S
T
P
N
V
V
S
Site 13
S139
Q
C
G
K
A
F
S
S
T
P
N
V
V
S
Q
Site 14
T140
C
G
K
A
F
S
S
T
P
N
V
V
S
Q
Q
Site 15
S145
S
S
T
P
N
V
V
S
Q
Q
A
C
T
R
D
Site 16
T150
V
V
S
Q
Q
A
C
T
R
D
R
S
L
D
Y
Site 17
S154
Q
A
C
T
R
D
R
S
L
D
Y
S
S
C
G
Site 18
Y157
T
R
D
R
S
L
D
Y
S
S
C
G
E
V
F
Site 19
S158
R
D
R
S
L
D
Y
S
S
C
G
E
V
F
L
Site 20
S176
Y
L
Q
A
R
A
G
S
H
N
G
E
E
T
W
Site 21
T193
K
P
C
G
K
A
L
T
H
S
M
G
C
A
T
Site 22
Y222
E
C
G
K
A
F
R
Y
T
A
Y
L
T
G
R
Site 23
T223
C
G
K
A
F
R
Y
T
A
Y
L
T
G
R
V
Site 24
Y225
K
A
F
R
Y
T
A
Y
L
T
G
R
V
Q
V
Site 25
T227
F
R
Y
T
A
Y
L
T
G
R
V
Q
V
H
P
Site 26
S248
L
E
E
C
G
K
A
S
P
V
S
S
S
L
T
Site 27
S251
C
G
K
A
S
P
V
S
S
S
L
T
Q
H
V
Site 28
S252
G
K
A
S
P
V
S
S
S
L
T
Q
H
V
R
Site 29
S253
K
A
S
P
V
S
S
S
L
T
Q
H
V
R
I
Site 30
T255
S
P
V
S
S
S
L
T
Q
H
V
R
I
H
A
Site 31
S280
G
K
A
F
T
G
L
S
G
L
S
K
H
V
Q
Site 32
Y295
T
D
P
G
Q
K
P
Y
E
C
K
D
C
G
K
Site 33
Y308
G
K
A
C
G
G
F
Y
L
L
N
E
H
G
K
Site 34
T316
L
L
N
E
H
G
K
T
H
T
R
E
K
P
F
Site 35
S336
G
K
Y
F
R
N
S
S
C
L
N
N
H
V
R
Site 36
T346
N
N
H
V
R
I
H
T
G
I
K
P
Y
T
C
Site 37
Y351
I
H
T
G
I
K
P
Y
T
C
S
Y
C
G
K
Site 38
T361
S
Y
C
G
K
A
F
T
V
R
C
G
L
T
R
Site 39
T374
T
R
H
V
R
T
H
T
G
E
K
P
Y
T
C
Site 40
T380
H
T
G
E
K
P
Y
T
C
K
D
C
G
K
A
Site 41
S392
G
K
A
F
C
T
S
S
G
L
T
E
H
V
R
Site 42
T395
F
C
T
S
S
G
L
T
E
H
V
R
T
H
T
Site 43
T400
G
L
T
E
H
V
R
T
H
T
G
E
K
P
Y
Site 44
T402
T
E
H
V
R
T
H
T
G
E
K
P
Y
E
C
Site 45
Y407
T
H
T
G
E
K
P
Y
E
C
K
D
C
G
K
Site 46
S415
E
C
K
D
C
G
K
S
F
T
V
S
S
S
L
Site 47
T417
K
D
C
G
K
S
F
T
V
S
S
S
L
T
E
Site 48
S419
C
G
K
S
F
T
V
S
S
S
L
T
E
H
A
Site 49
S420
G
K
S
F
T
V
S
S
S
L
T
E
H
A
R
Site 50
S421
K
S
F
T
V
S
S
S
L
T
E
H
A
R
I
Site 51
T423
F
T
V
S
S
S
L
T
E
H
A
R
I
H
T
Site 52
T430
T
E
H
A
R
I
H
T
G
E
K
P
Y
E
C
Site 53
Y435
I
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 54
T445
K
Q
C
G
K
A
F
T
G
R
S
G
L
T
K
Site 55
S448
G
K
A
F
T
G
R
S
G
L
T
K
H
M
R
Site 56
T458
T
K
H
M
R
T
H
T
G
E
K
P
Y
E
C
Site 57
Y472
C
K
D
C
G
K
A
Y
N
R
V
Y
L
L
N
Site 58
Y476
G
K
A
Y
N
R
V
Y
L
L
N
E
H
V
K
Site 59
T484
L
L
N
E
H
V
K
T
H
T
E
E
K
P
F
Site 60
T492
H
T
E
E
K
P
F
T
C
T
V
C
R
K
S
Site 61
T494
E
E
K
P
F
T
C
T
V
C
R
K
S
F
R
Site 62
S503
C
R
K
S
F
R
N
S
S
C
L
N
K
H
I
Site 63
S504
R
K
S
F
R
N
S
S
C
L
N
K
H
I
H
Site 64
Y519
I
H
T
G
I
K
P
Y
E
C
K
D
C
G
K
Site 65
T527
E
C
K
D
C
G
K
T
F
T
V
S
S
S
L
Site 66
T529
K
D
C
G
K
T
F
T
V
S
S
S
L
T
E
Site 67
S531
C
G
K
T
F
T
V
S
S
S
L
T
E
H
I
Site 68
S532
G
K
T
F
T
V
S
S
S
L
T
E
H
I
R
Site 69
S533
K
T
F
T
V
S
S
S
L
T
E
H
I
R
T
Site 70
T535
F
T
V
S
S
S
L
T
E
H
I
R
T
H
T
Site 71
T540
S
L
T
E
H
I
R
T
H
T
G
E
K
P
Y
Site 72
T542
T
E
H
I
R
T
H
T
G
E
K
P
Y
E
C
Site 73
Y547
T
H
T
G
E
K
P
Y
E
C
K
V
C
G
K
Site 74
T570
I
V
H
I
R
T
H
T
G
E
K
P
Y
I
C
Site 75
Y575
T
H
T
G
E
K
P
Y
I
C
K
E
C
G
K
Site 76
S586
E
C
G
K
A
F
A
S
S
S
H
L
I
E
H
Site 77
S588
G
K
A
F
A
S
S
S
H
L
I
E
H
R
R
Site 78
T596
H
L
I
E
H
R
R
T
H
T
G
E
K
P
Y
Site 79
T598
I
E
H
R
R
T
H
T
G
E
K
P
Y
I
C
Site 80
Y603
T
H
T
G
E
K
P
Y
I
C
N
E
C
G
K
Site 81
S615
C
G
K
A
F
R
A
S
S
H
L
H
K
H
G
Site 82
S616
G
K
A
F
R
A
S
S
H
L
H
K
H
G
R
Site 83
T626
H
K
H
G
R
I
H
T
G
Q
K
P
Y
K
C
Site 84
Y640
C
K
E
C
G
K
A
Y
N
R
F
Y
L
L
K
Site 85
Y644
G
K
A
Y
N
R
F
Y
L
L
K
E
H
L
K
Site 86
T652
L
L
K
E
H
L
K
T
Y
T
E
E
Q
V
F
Site 87
S672
G
K
S
F
K
N
S
S
C
L
N
H
H
T
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation