KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF553
Full Name:
Zinc finger protein 48
Alias:
DKFZp762K013; FLJ31751; MGC43952; Zinc finger protein 553; ZN553
Type:
Mass (Da):
67833
Number AA:
618
UniProt ID:
Q96MX3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
G
A
R
T
G
L
G
S
E
N
V
I
S
Q
P
Site 2
S35
L
G
S
E
N
V
I
S
Q
P
N
E
F
E
H
Site 3
T43
Q
P
N
E
F
E
H
T
P
Q
E
D
D
L
G
Site 4
S66
D
H
E
V
G
N
V
S
L
K
P
E
G
I
Q
Site 5
S107
E
P
R
W
G
Q
A
S
S
D
R
A
A
V
C
Site 6
S108
P
R
W
G
Q
A
S
S
D
R
A
A
V
C
G
Site 7
S125
G
K
S
F
R
Q
M
S
D
L
V
K
H
Q
R
Site 8
T133
D
L
V
K
H
Q
R
T
H
T
G
E
K
P
Y
Site 9
T135
V
K
H
Q
R
T
H
T
G
E
K
P
Y
K
C
Site 10
Y140
T
H
T
G
E
K
P
Y
K
C
G
V
C
G
K
Site 11
S152
C
G
K
G
F
G
D
S
S
A
R
I
K
H
Q
Site 12
S153
G
K
G
F
G
D
S
S
A
R
I
K
H
Q
R
Site 13
T161
A
R
I
K
H
Q
R
T
H
S
G
E
K
P
Y
Site 14
S163
I
K
H
Q
R
T
H
S
G
E
K
P
Y
R
A
Site 15
S183
G
P
P
K
I
P
R
S
R
I
P
A
G
E
R
Site 16
T192
I
P
A
G
E
R
P
T
I
C
G
E
C
G
K
Site 17
S200
I
C
G
E
C
G
K
S
F
R
L
S
S
D
L
Site 18
S204
C
G
K
S
F
R
L
S
S
D
L
V
K
H
Q
Site 19
S205
G
K
S
F
R
L
S
S
D
L
V
K
H
Q
R
Site 20
Y220
T
H
T
G
E
K
P
Y
K
C
G
I
C
G
K
Site 21
T241
A
R
I
K
H
Q
R
T
H
R
G
E
Q
P
P
Site 22
S258
V
V
P
R
R
Q
P
S
R
A
A
T
A
A
T
Site 23
T262
R
Q
P
S
R
A
A
T
A
A
T
Q
G
P
K
Site 24
Y275
P
K
A
Q
D
K
P
Y
I
C
T
D
C
G
K
Site 25
S289
K
R
F
V
L
S
C
S
L
L
S
H
Q
R
S
Site 26
S296
S
L
L
S
H
Q
R
S
H
L
G
P
K
P
F
Site 27
S316
G
K
E
F
A
R
G
S
D
L
V
K
H
L
R
Site 28
T326
V
K
H
L
R
V
H
T
G
E
K
P
Y
L
C
Site 29
Y331
V
H
T
G
E
K
P
Y
L
C
P
E
C
G
K
Site 30
S343
C
G
K
G
F
A
D
S
S
A
R
V
K
H
L
Site 31
S344
G
K
G
F
A
D
S
S
A
R
V
K
H
L
R
Site 32
S354
V
K
H
L
R
T
H
S
G
E
R
P
H
A
C
Site 33
T367
A
C
P
E
C
D
R
T
F
S
L
S
S
T
L
Site 34
S369
P
E
C
D
R
T
F
S
L
S
S
T
L
L
R
Site 35
S371
C
D
R
T
F
S
L
S
S
T
L
L
R
H
R
Site 36
T373
R
T
F
S
L
S
S
T
L
L
R
H
R
L
T
Site 37
T380
T
L
L
R
H
R
L
T
H
M
E
P
Q
D
F
Site 38
S388
H
M
E
P
Q
D
F
S
F
P
G
Y
P
L
P
Site 39
S400
P
L
P
A
L
I
P
S
P
P
P
P
P
L
G
Site 40
T408
P
P
P
P
P
L
G
T
S
P
P
L
T
P
R
Site 41
S409
P
P
P
P
L
G
T
S
P
P
L
T
P
R
S
Site 42
T413
L
G
T
S
P
P
L
T
P
R
S
P
S
H
S
Site 43
S416
S
P
P
L
T
P
R
S
P
S
H
S
G
E
P
Site 44
S418
P
L
T
P
R
S
P
S
H
S
G
E
P
F
G
Site 45
S420
T
P
R
S
P
S
H
S
G
E
P
F
G
L
P
Site 46
S463
C
G
K
G
F
R
R
S
S
D
L
V
K
H
H
Site 47
S464
G
K
G
F
R
R
S
S
D
L
V
K
H
H
R
Site 48
T474
V
K
H
H
R
V
H
T
G
E
K
P
Y
L
C
Site 49
T500
A
R
V
K
H
L
R
T
H
R
G
E
R
A
R
Site 50
S512
R
A
R
P
P
P
P
S
T
L
L
R
P
H
N
Site 51
T513
A
R
P
P
P
P
S
T
L
L
R
P
H
N
P
Site 52
S537
P
R
V
R
A
Q
P
S
G
P
S
Q
P
H
V
Site 53
S540
R
A
Q
P
S
G
P
S
Q
P
H
V
C
G
F
Site 54
S555
C
G
K
E
F
P
R
S
S
D
L
V
K
H
R
Site 55
S556
G
K
E
F
P
R
S
S
D
L
V
K
H
R
R
Site 56
T564
D
L
V
K
H
R
R
T
H
T
G
E
K
P
Y
Site 57
T566
V
K
H
R
R
T
H
T
G
E
K
P
Y
K
C
Site 58
Y571
T
H
T
G
E
K
P
Y
K
C
A
E
C
G
K
Site 59
T597
Q
R
G
H
L
V
L
T
P
F
G
I
G
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation