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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BROMI
Full Name:
Protein broad-minded
Alias:
Type:
Mass (Da):
144756
Number AA:
1257
UniProt ID:
Q96NH3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
M
L
R
R
L
F
Q
S
V
K
E
K
I
T
G
Site 2
T28
Q
S
V
K
E
K
I
T
G
A
P
S
L
E
C
Site 3
S32
E
K
I
T
G
A
P
S
L
E
C
A
E
E
I
Site 4
T46
I
L
L
H
L
E
E
T
D
E
N
F
H
N
Y
Site 5
Y53
T
D
E
N
F
H
N
Y
E
F
V
K
Y
L
R
Site 6
Y58
H
N
Y
E
F
V
K
Y
L
R
Q
H
I
G
N
Site 7
S69
H
I
G
N
T
L
G
S
M
I
E
E
E
M
E
Site 8
S80
E
E
M
E
K
C
T
S
D
R
N
Q
G
E
E
Site 9
Y90
N
Q
G
E
E
C
G
Y
D
T
V
V
Q
Q
V
Site 10
T92
G
E
E
C
G
Y
D
T
V
V
Q
Q
V
T
K
Site 11
Y107
R
T
Q
E
S
K
E
Y
K
E
M
M
H
Y
L
Site 12
Y113
E
Y
K
E
M
M
H
Y
L
K
N
I
M
I
A
Site 13
T134
N
K
F
E
E
D
E
T
R
N
Q
E
R
Q
K
Site 14
S148
K
K
I
Q
K
E
K
S
H
S
Y
R
T
D
N
Site 15
S150
I
Q
K
E
K
S
H
S
Y
R
T
D
N
C
S
Site 16
T153
E
K
S
H
S
Y
R
T
D
N
C
S
D
S
D
Site 17
S157
S
Y
R
T
D
N
C
S
D
S
D
S
S
L
N
Site 18
S159
R
T
D
N
C
S
D
S
D
S
S
L
N
Q
S
Site 19
S161
D
N
C
S
D
S
D
S
S
L
N
Q
S
Y
K
Site 20
S162
N
C
S
D
S
D
S
S
L
N
Q
S
Y
K
F
Site 21
S166
S
D
S
S
L
N
Q
S
Y
K
F
C
Q
G
K
Site 22
T196
V
R
Y
E
A
L
Q
T
L
C
S
A
P
P
S
Site 23
S203
T
L
C
S
A
P
P
S
D
V
L
N
C
E
N
Site 24
T219
T
T
L
C
E
K
L
T
V
S
L
S
D
P
D
Site 25
S221
L
C
E
K
L
T
V
S
L
S
D
P
D
P
V
Site 26
S223
E
K
L
T
V
S
L
S
D
P
D
P
V
F
S
Site 27
S230
S
D
P
D
P
V
F
S
D
R
I
L
K
F
C
Site 28
S255
M
T
K
E
I
Y
T
S
L
A
K
Y
L
E
S
Site 29
S262
S
L
A
K
Y
L
E
S
Y
F
L
S
R
E
N
Site 30
Y263
L
A
K
Y
L
E
S
Y
F
L
S
R
E
N
H
Site 31
S266
Y
L
E
S
Y
F
L
S
R
E
N
H
I
P
T
Site 32
T281
L
S
A
G
V
D
I
T
N
P
N
M
T
R
L
Site 33
Y298
K
V
R
L
L
N
E
Y
Q
K
E
A
P
S
F
Site 34
Y313
W
I
R
H
P
E
K
Y
M
E
E
I
V
E
S
Site 35
T326
E
S
T
L
S
L
L
T
V
K
H
N
Q
S
H
Site 36
S332
L
T
V
K
H
N
Q
S
H
V
V
S
Q
K
I
Site 37
S336
H
N
Q
S
H
V
V
S
Q
K
I
L
D
P
I
Site 38
Y364
K
K
W
M
H
A
H
Y
S
R
T
T
V
L
R
Site 39
T368
H
A
H
Y
S
R
T
T
V
L
R
L
L
E
K
Site 40
Y377
L
R
L
L
E
K
K
Y
K
S
L
V
T
T
A
Site 41
S379
L
L
E
K
K
Y
K
S
L
V
T
T
A
I
Q
Site 42
T383
K
Y
K
S
L
V
T
T
A
I
Q
Q
C
V
Q
Site 43
T403
K
T
R
K
A
D
E
T
L
G
H
S
K
H
C
Site 44
Y418
R
N
K
Q
K
T
F
Y
Y
L
G
Q
E
L
Q
Site 45
Y419
N
K
Q
K
T
F
Y
Y
L
G
Q
E
L
Q
Y
Site 46
S478
Q
L
I
Y
Y
S
P
S
C
P
K
M
T
S
A
Site 47
S484
P
S
C
P
K
M
T
S
A
A
H
S
E
N
Y
Site 48
S488
K
M
T
S
A
A
H
S
E
N
Y
S
P
A
S
Site 49
S492
A
A
H
S
E
N
Y
S
P
A
S
M
V
T
E
Site 50
S495
S
E
N
Y
S
P
A
S
M
V
T
E
V
L
W
Site 51
S538
L
M
K
G
N
E
A
S
P
N
C
S
E
T
A
Site 52
S542
N
E
A
S
P
N
C
S
E
T
A
L
I
H
I
Site 53
S574
L
Y
G
A
N
M
N
S
S
E
E
S
P
T
G
Site 54
S575
Y
G
A
N
M
N
S
S
E
E
S
P
T
G
A
Site 55
S578
N
M
N
S
S
E
E
S
P
T
G
A
H
I
I
Site 56
S589
A
H
I
I
A
Q
F
S
K
K
L
L
D
E
D
Site 57
S598
K
L
L
D
E
D
I
S
I
F
S
G
S
E
M
Site 58
S647
A
K
A
W
K
K
T
S
L
L
S
E
R
I
P
Site 59
S650
W
K
K
T
S
L
L
S
E
R
I
P
T
P
V
Site 60
T655
L
L
S
E
R
I
P
T
P
V
E
G
S
D
S
Site 61
S660
I
P
T
P
V
E
G
S
D
S
V
S
S
V
S
Site 62
S662
T
P
V
E
G
S
D
S
V
S
S
V
S
Q
E
Site 63
S664
V
E
G
S
D
S
V
S
S
V
S
Q
E
S
Q
Site 64
S665
E
G
S
D
S
V
S
S
V
S
Q
E
S
Q
N
Site 65
S667
S
D
S
V
S
S
V
S
Q
E
S
Q
N
I
M
Site 66
Y728
S
R
H
K
K
F
G
Y
G
V
L
V
T
R
V
Site 67
Y764
E
L
W
S
N
L
E
Y
G
R
D
D
V
R
V
Site 68
T772
G
R
D
D
V
R
V
T
H
P
R
T
T
P
V
Site 69
T776
V
R
V
T
H
P
R
T
T
P
V
D
P
I
D
Site 70
T777
R
V
T
H
P
R
T
T
P
V
D
P
I
D
R
Site 71
S785
P
V
D
P
I
D
R
S
C
Q
K
S
F
L
A
Site 72
S789
I
D
R
S
C
Q
K
S
F
L
A
L
V
N
L
Site 73
S818
L
P
N
K
T
E
Y
S
L
R
E
V
P
T
C
Site 74
S838
D
R
L
I
I
L
N
S
E
A
K
I
R
S
L
Site 75
S844
N
S
E
A
K
I
R
S
L
F
N
Y
E
Q
S
Site 76
Y848
K
I
R
S
L
F
N
Y
E
Q
S
H
I
F
G
Site 77
S894
P
P
R
L
L
E
K
S
D
N
P
Y
P
W
P
Site 78
Y898
L
E
K
S
D
N
P
Y
P
W
P
M
F
S
S
Site 79
Y912
S
Y
P
L
P
N
C
Y
L
S
D
I
T
R
N
Site 80
S914
P
L
P
N
C
Y
L
S
D
I
T
R
N
A
G
Site 81
T980
E
K
F
V
L
H
L
T
E
S
P
S
E
C
Y
Site 82
S984
L
H
L
T
E
S
P
S
E
C
Y
F
P
S
V
Site 83
Y987
T
E
S
P
S
E
C
Y
F
P
S
V
E
Y
T
Site 84
T994
Y
F
P
S
V
E
Y
T
A
T
D
A
N
V
K
Site 85
T996
P
S
V
E
Y
T
A
T
D
A
N
V
K
N
E
Site 86
S1004
D
A
N
V
K
N
E
S
L
S
S
V
Q
Q
L
Site 87
S1006
N
V
K
N
E
S
L
S
S
V
Q
Q
L
G
I
Site 88
S1007
V
K
N
E
S
L
S
S
V
Q
Q
L
G
I
K
Site 89
T1016
Q
Q
L
G
I
K
M
T
V
R
Y
G
K
F
L
Site 90
S1024
V
R
Y
G
K
F
L
S
L
L
K
D
G
A
E
Site 91
T1050
R
F
L
K
Q
Q
Q
T
S
I
K
S
S
L
L
Site 92
S1051
F
L
K
Q
Q
Q
T
S
I
K
S
S
L
L
C
Site 93
S1055
Q
Q
T
S
I
K
S
S
L
L
C
L
Q
G
N
Site 94
S1109
L
P
R
L
H
I
S
S
Y
L
P
N
D
T
V
Site 95
Y1110
P
R
L
H
I
S
S
Y
L
P
N
D
T
V
E
Site 96
T1115
S
S
Y
L
P
N
D
T
V
E
S
G
I
H
P
Site 97
Y1124
E
S
G
I
H
P
V
Y
F
C
S
T
H
Y
I
Site 98
Y1230
H
G
F
R
V
S
D
Y
F
E
Y
M
E
I
L
Site 99
Y1233
R
V
S
D
Y
F
E
Y
M
E
I
L
E
Q
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation