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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRFN5
Full Name:
Leucine-rich repeat and fibronectin type-III domain-containing protein 5
Alias:
Leucine-rich repeat and fibronectin type-III domain-containing 5
Type:
Membrane, Cytoplasm, Nucleus, Integral membrane protein
Mass (Da):
79445
Number AA:
719
UniProt ID:
Q96NI6
International Prot ID:
IPI00396961
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S83
S
L
V
D
L
T
L
S
R
N
T
I
S
F
I
Site 2
S567
Q
H
K
V
T
K
V
S
N
V
Y
S
Q
T
N
Site 3
Y570
V
T
K
V
S
N
V
Y
S
Q
T
N
G
A
Q
Site 4
S571
T
K
V
S
N
V
Y
S
Q
T
N
G
A
Q
I
Site 5
S582
G
A
Q
I
Q
G
C
S
V
T
L
P
Q
S
V
Site 6
T584
Q
I
Q
G
C
S
V
T
L
P
Q
S
V
S
K
Site 7
S588
C
S
V
T
L
P
Q
S
V
S
K
Q
A
V
G
Site 8
S590
V
T
L
P
Q
S
V
S
K
Q
A
V
G
H
E
Site 9
S614
S
D
N
V
I
Q
S
S
E
T
C
S
S
Q
D
Site 10
S618
I
Q
S
S
E
T
C
S
S
Q
D
S
S
T
T
Site 11
S619
Q
S
S
E
T
C
S
S
Q
D
S
S
T
T
T
Site 12
S622
E
T
C
S
S
Q
D
S
S
T
T
T
S
A
L
Site 13
S623
T
C
S
S
Q
D
S
S
T
T
T
S
A
L
P
Site 14
T624
C
S
S
Q
D
S
S
T
T
T
S
A
L
P
P
Site 15
T625
S
S
Q
D
S
S
T
T
T
S
A
L
P
P
S
Site 16
T626
S
Q
D
S
S
T
T
T
S
A
L
P
P
S
W
Site 17
S627
Q
D
S
S
T
T
T
S
A
L
P
P
S
W
T
Site 18
S632
T
T
S
A
L
P
P
S
W
T
S
S
T
S
V
Site 19
T634
S
A
L
P
P
S
W
T
S
S
T
S
V
S
Q
Site 20
S635
A
L
P
P
S
W
T
S
S
T
S
V
S
Q
K
Site 21
S636
L
P
P
S
W
T
S
S
T
S
V
S
Q
K
Q
Site 22
S638
P
S
W
T
S
S
T
S
V
S
Q
K
Q
K
R
Site 23
S640
W
T
S
S
T
S
V
S
Q
K
Q
K
R
K
T
Site 24
T647
S
Q
K
Q
K
R
K
T
G
T
K
P
S
T
E
Site 25
S652
R
K
T
G
T
K
P
S
T
E
P
Q
N
E
A
Site 26
T668
T
N
V
E
S
Q
N
T
N
R
N
N
S
T
A
Site 27
S673
Q
N
T
N
R
N
N
S
T
A
L
Q
L
A
S
Site 28
S680
S
T
A
L
Q
L
A
S
R
P
P
D
S
V
T
Site 29
S685
L
A
S
R
P
P
D
S
V
T
E
G
P
T
S
Site 30
T687
S
R
P
P
D
S
V
T
E
G
P
T
S
K
R
Site 31
S692
S
V
T
E
G
P
T
S
K
R
A
H
I
K
P
Site 32
T713
V
D
Q
I
V
Q
E
T
Q
R
L
E
L
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation