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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL32
Full Name:
Kelch-like protein 32
Alias:
BTB and kelch domain-containing protein 5
Type:
Mass (Da):
70362
Number AA:
620
UniProt ID:
Q96NJ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
S
E
R
C
L
S
I
Q
E
M
L
T
G
Site 2
T14
L
S
I
Q
E
M
L
T
G
Q
R
L
C
H
S
Site 3
S21
T
G
Q
R
L
C
H
S
E
S
H
N
D
S
V
Site 4
S23
Q
R
L
C
H
S
E
S
H
N
D
S
V
L
A
Site 5
S27
H
S
E
S
H
N
D
S
V
L
A
A
L
N
Q
Site 6
S37
A
A
L
N
Q
Q
R
S
D
G
I
L
C
D
I
Site 7
Y144
Q
E
L
N
S
F
N
Y
L
D
L
Y
R
L
A
Site 8
Y148
S
F
N
Y
L
D
L
Y
R
L
A
D
L
F
N
Site 9
S172
D
F
L
V
K
H
L
S
E
L
L
K
S
R
P
Site 10
S177
H
L
S
E
L
L
K
S
R
P
E
E
V
L
T
Site 11
T184
S
R
P
E
E
V
L
T
L
P
Y
C
L
L
Q
Site 12
S196
L
L
Q
E
V
L
K
S
D
R
L
T
S
L
S
Site 13
T200
V
L
K
S
D
R
L
T
S
L
S
E
E
Q
I
Site 14
S201
L
K
S
D
R
L
T
S
L
S
E
E
Q
I
W
Site 15
S203
S
D
R
L
T
S
L
S
E
E
Q
I
W
Q
L
Site 16
Y267
L
V
N
E
A
L
E
Y
H
Q
S
I
Y
A
Q
Site 17
Y272
L
E
Y
H
Q
S
I
Y
A
Q
P
V
W
Q
T
Site 18
T282
P
V
W
Q
T
R
R
T
K
P
R
F
Q
S
D
Site 19
S288
R
T
K
P
R
F
Q
S
D
T
L
Y
I
I
G
Site 20
T290
K
P
R
F
Q
S
D
T
L
Y
I
I
G
G
K
Site 21
Y292
R
F
Q
S
D
T
L
Y
I
I
G
G
K
K
R
Site 22
Y309
C
K
V
K
E
L
R
Y
F
N
P
V
D
Q
E
Site 23
S359
G
G
E
V
E
H
A
S
G
R
T
C
A
V
R
Site 24
Y371
A
V
R
T
A
C
R
Y
D
P
R
S
N
S
W
Site 25
S375
A
C
R
Y
D
P
R
S
N
S
W
A
E
I
A
Site 26
S377
R
Y
D
P
R
S
N
S
W
A
E
I
A
P
M
Site 27
Y399
V
L
G
A
M
E
E
Y
L
Y
A
V
G
G
R
Site 28
Y401
G
A
M
E
E
Y
L
Y
A
V
G
G
R
N
E
Site 29
T415
E
L
R
Q
V
L
P
T
V
E
R
Y
C
P
K
Site 30
S431
N
K
W
T
F
V
Q
S
F
D
R
S
L
S
C
Site 31
S435
F
V
Q
S
F
D
R
S
L
S
C
H
A
G
Y
Site 32
S437
Q
S
F
D
R
S
L
S
C
H
A
G
Y
V
A
Site 33
T455
L
W
I
S
G
G
V
T
N
T
A
Q
Y
Q
N
Site 34
Y460
G
V
T
N
T
A
Q
Y
Q
N
R
L
M
V
Y
Site 35
Y467
Y
Q
N
R
L
M
V
Y
E
P
N
Q
N
K
W
Site 36
S476
P
N
Q
N
K
W
I
S
R
S
P
M
L
Q
R
Site 37
S478
Q
N
K
W
I
S
R
S
P
M
L
Q
R
R
V
Site 38
Y486
P
M
L
Q
R
R
V
Y
H
S
M
A
A
V
Q
Site 39
S488
L
Q
R
R
V
Y
H
S
M
A
A
V
Q
R
K
Site 40
Y506
L
G
G
N
D
L
D
Y
N
N
D
R
I
L
V
Site 41
Y519
L
V
R
H
I
D
S
Y
N
I
D
T
D
Q
W
Site 42
T535
R
C
N
F
N
L
L
T
G
Q
N
E
S
G
V
Site 43
S572
C
I
Q
V
L
D
V
S
R
E
G
K
E
E
V
Site 44
Y581
E
G
K
E
E
V
F
Y
G
P
T
L
P
F
A
Site 45
T584
E
E
V
F
Y
G
P
T
L
P
F
A
S
N
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation