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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NEUROD6
Full Name:
Neurogenic differentiation factor 6
Alias:
Class A basic helix-loop-helix protein 2;Protein atonal homolog 2
Type:
Mass (Da):
38705
Number AA:
337
UniProt ID:
Q96NK8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
L
T
L
P
F
D
E
S
V
V
M
P
E
S
Q
Site 2
S15
E
S
V
V
M
P
E
S
Q
M
C
R
K
F
S
Site 3
S22
S
Q
M
C
R
K
F
S
R
E
C
E
D
Q
K
Site 4
S36
K
Q
I
K
K
P
E
S
F
S
K
Q
I
V
L
Site 5
S47
Q
I
V
L
R
G
K
S
I
K
R
A
P
G
E
Site 6
T84
R
G
L
R
K
K
K
T
T
K
L
R
L
E
R
Site 7
T85
G
L
R
K
K
K
T
T
K
L
R
L
E
R
V
Site 8
S125
R
K
V
V
P
C
Y
S
K
T
Q
K
L
S
K
Site 9
T127
V
V
P
C
Y
S
K
T
Q
K
L
S
K
I
E
Site 10
T135
Q
K
L
S
K
I
E
T
L
R
L
A
K
N
Y
Site 11
T160
G
K
R
P
D
L
L
T
F
V
Q
N
L
C
K
Site 12
S170
Q
N
L
C
K
G
L
S
Q
P
T
T
N
L
V
Site 13
T200
G
G
E
A
A
H
H
T
R
S
P
Y
S
T
F
Site 14
S202
E
A
A
H
H
T
R
S
P
Y
S
T
F
Y
P
Site 15
Y204
A
H
H
T
R
S
P
Y
S
T
F
Y
P
P
Y
Site 16
T206
H
T
R
S
P
Y
S
T
F
Y
P
P
Y
H
S
Site 17
Y208
R
S
P
Y
S
T
F
Y
P
P
Y
H
S
P
E
Site 18
Y211
Y
S
T
F
Y
P
P
Y
H
S
P
E
L
T
T
Site 19
S213
T
F
Y
P
P
Y
H
S
P
E
L
T
T
P
P
Site 20
T217
P
Y
H
S
P
E
L
T
T
P
P
G
H
G
T
Site 21
T218
Y
H
S
P
E
L
T
T
P
P
G
H
G
T
L
Site 22
T224
T
T
P
P
G
H
G
T
L
D
N
S
K
S
M
Site 23
S228
G
H
G
T
L
D
N
S
K
S
M
K
P
Y
N
Site 24
Y234
N
S
K
S
M
K
P
Y
N
Y
C
S
A
Y
E
Site 25
Y236
K
S
M
K
P
Y
N
Y
C
S
A
Y
E
S
F
Site 26
Y240
P
Y
N
Y
C
S
A
Y
E
S
F
Y
E
S
T
Site 27
S242
N
Y
C
S
A
Y
E
S
F
Y
E
S
T
S
P
Site 28
Y244
C
S
A
Y
E
S
F
Y
E
S
T
S
P
E
C
Site 29
S246
A
Y
E
S
F
Y
E
S
T
S
P
E
C
A
S
Site 30
S248
E
S
F
Y
E
S
T
S
P
E
C
A
S
P
Q
Site 31
S253
S
T
S
P
E
C
A
S
P
Q
F
E
G
P
L
Site 32
S261
P
Q
F
E
G
P
L
S
P
P
P
I
N
Y
N
Site 33
Y267
L
S
P
P
P
I
N
Y
N
G
I
F
S
L
K
Site 34
S272
I
N
Y
N
G
I
F
S
L
K
Q
E
E
T
L
Site 35
T278
F
S
L
K
Q
E
E
T
L
D
Y
G
K
N
Y
Site 36
Y281
K
Q
E
E
T
L
D
Y
G
K
N
Y
N
Y
G
Site 37
Y285
T
L
D
Y
G
K
N
Y
N
Y
G
M
H
Y
C
Site 38
Y287
D
Y
G
K
N
Y
N
Y
G
M
H
Y
C
A
V
Site 39
Y291
N
Y
N
Y
G
M
H
Y
C
A
V
P
P
R
G
Site 40
T310
G
A
M
F
R
L
P
T
D
S
H
F
P
Y
D
Site 41
Y316
P
T
D
S
H
F
P
Y
D
L
H
L
R
S
Q
Site 42
S322
P
Y
D
L
H
L
R
S
Q
S
L
T
M
Q
D
Site 43
S324
D
L
H
L
R
S
Q
S
L
T
M
Q
D
E
L
Site 44
T326
H
L
R
S
Q
S
L
T
M
Q
D
E
L
N
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation