KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RDH12
Full Name:
Retinol dehydrogenase 12
Alias:
Flj30273; Lca3; Rdh12; Retinol dehydrogenase 12 (all-trans/9-cis/11-cis); Sdr7c2; Short chain dehydrogenase/reductase family 7C, member 2
Type:
Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.-
Mass (Da):
35094
Number AA:
316
UniProt ID:
Q96NR8
International Prot ID:
IPI00163384
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0004745
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0045494
GO:0050896
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S81
L
K
G
E
S
A
A
S
E
I
R
V
D
T
K
Site 2
T87
A
S
E
I
R
V
D
T
K
N
S
Q
V
L
V
Site 3
S100
L
V
R
K
L
D
L
S
D
T
K
S
I
R
A
Site 4
T102
R
K
L
D
L
S
D
T
K
S
I
R
A
F
A
Site 5
S104
L
D
L
S
D
T
K
S
I
R
A
F
A
E
G
Site 6
S190
I
P
F
H
D
L
Q
S
E
K
R
Y
S
R
G
Site 7
Y194
D
L
Q
S
E
K
R
Y
S
R
G
F
A
Y
C
Site 8
S195
L
Q
S
E
K
R
Y
S
R
G
F
A
Y
C
H
Site 9
Y200
R
Y
S
R
G
F
A
Y
C
H
S
K
L
A
N
Site 10
T225
L
Q
G
T
G
V
T
T
Y
A
V
H
P
G
V
Site 11
S235
V
H
P
G
V
V
R
S
E
L
V
R
H
S
S
Site 12
T257
L
F
S
P
F
V
K
T
A
R
E
G
A
Q
T
Site 13
T264
T
A
R
E
G
A
Q
T
S
L
H
C
A
L
A
Site 14
S265
A
R
E
G
A
Q
T
S
L
H
C
A
L
A
E
Site 15
S278
A
E
G
L
E
P
L
S
G
K
Y
F
S
D
C
Site 16
Y281
L
E
P
L
S
G
K
Y
F
S
D
C
K
R
T
Site 17
S283
P
L
S
G
K
Y
F
S
D
C
K
R
T
W
V
Site 18
S291
D
C
K
R
T
W
V
S
P
R
A
R
N
N
K
Site 19
T299
P
R
A
R
N
N
K
T
A
E
R
L
W
N
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation