PhosphoNET

           
Protein Info 
   
Short Name:  MUS81
Full Name:  Crossover junction endonuclease MUS81
Alias:  FLJ44872; MUS81 endonuclease
Type:  Deoxyribonuclease; EC 3.1.22.-
Mass (Da):  61173
Number AA:  551
UniProt ID:  Q96NY9
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005730     Uniprot OncoNet
Molecular Function:  GO:0048257  GO:0003677  GO:0000287 PhosphoSite+ KinaseNET
Biological Process:  GO:0006310  GO:0006281   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T26PLFVRWLTEWRDEAT
Site 2S35WRDEATRSRRRTRFV
Site 3T39ATRSRRRTRFVFQKA
Site 4S49VFQKALRSLRRYPLP
Site 5Y53ALRSLRRYPLPLRSG
Site 6T86ERLQRHRTSGGDHAP
Site 7S87RLQRHRTSGGDHAPD
Site 8S95GGDHAPDSPSGENSP
Site 9S97DHAPDSPSGENSPAP
Site 10S101DSPSGENSPAPQGRL
Site 11S114RLAEVQDSSMPVPAQ
Site 12S127AQPKAGGSGSYWPAR
Site 13S129PKAGGSGSYWPARHS
Site 14S136SYWPARHSGARVILL
Site 15T159PNGHHFLTKEELLQR
Site 16S171LQRCAQKSPRVAPGS
Site 17S178SPRVAPGSARPWPAL
Site 18S204THQPARYSLTPEGLE
Site 19T206QPARYSLTPEGLELA
Site 20T299QRLHVTHTVRKLHVG
Site 21S342KRLDDLCSSIIDGRF
Site 22S343RLDDLCSSIIDGRFR
Site 23Y366CGLERRVYLVEEHGS
Site 24S373YLVEEHGSVHNLSLP
Site 25S378HGSVHNLSLPESTLL
Site 26Y423TRGLQRLYQGHTLRS
Site 27T427QRLYQGHTLRSRPWG
Site 28S430YQGHTLRSRPWGTPG
Site 29T435LRSRPWGTPGNPESG
Site 30S441GTPGNPESGAMTSPN
Site 31T445NPESGAMTSPNPLCS
Site 32S446PESGAMTSPNPLCSL
Site 33S470AIKNKAQSVREVFAR
Site 34S502DRYSTPASLLAAYDA
Site 35T512AAYDACATPKEQETL
Site 36S521KEQETLLSTIKCGRL
Site 37S537RNLGPALSRTLSQLY
Site 38S541PALSRTLSQLYCSYG
Site 39Y544SRTLSQLYCSYGPLT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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