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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WFIKKN1
Full Name:
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1
Alias:
Growth and differentiation factor-associated serum protein 2;WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing protein
Type:
Mass (Da):
58798
Number AA:
548
UniProt ID:
Q96NZ8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
G
V
C
P
N
Q
L
S
P
N
L
W
V
D
A
Site 2
T48
L
W
V
D
A
Q
S
T
C
E
R
E
C
S
R
Site 3
S54
S
T
C
E
R
E
C
S
R
D
Q
D
C
A
A
Site 4
T88
P
G
S
P
A
A
P
T
T
A
A
S
C
E
G
Site 5
T89
G
S
P
A
A
P
T
T
A
A
S
C
E
G
F
Site 6
S125
D
R
C
E
K
E
P
S
F
T
C
A
S
D
G
Site 7
T127
C
E
K
E
P
S
F
T
C
A
S
D
G
L
T
Site 8
Y135
C
A
S
D
G
L
T
Y
Y
N
R
C
Y
M
D
Site 9
Y136
A
S
D
G
L
T
Y
Y
N
R
C
Y
M
D
A
Site 10
Y140
L
T
Y
Y
N
R
C
Y
M
D
A
E
A
C
L
Site 11
S162
V
P
C
K
H
V
L
S
W
P
P
S
S
P
G
Site 12
S166
H
V
L
S
W
P
P
S
S
P
G
P
P
E
T
Site 13
S167
V
L
S
W
P
P
S
S
P
G
P
P
E
T
T
Site 14
T173
S
S
P
G
P
P
E
T
T
A
R
P
T
P
G
Site 15
T174
S
P
G
P
P
E
T
T
A
R
P
T
P
G
A
Site 16
T178
P
E
T
T
A
R
P
T
P
G
A
A
P
V
P
Site 17
Y189
A
P
V
P
P
A
L
Y
S
S
P
S
P
Q
A
Site 18
S190
P
V
P
P
A
L
Y
S
S
P
S
P
Q
A
V
Site 19
S191
V
P
P
A
L
Y
S
S
P
S
P
Q
A
V
Q
Site 20
S193
P
A
L
Y
S
S
P
S
P
Q
A
V
Q
V
G
Site 21
S210
A
S
L
H
C
D
V
S
G
R
P
P
P
A
V
Site 22
T218
G
R
P
P
P
A
V
T
W
E
K
Q
S
H
Q
Site 23
Y237
I
M
R
P
D
Q
M
Y
G
N
V
V
V
T
S
Site 24
Y251
S
I
G
Q
L
V
L
Y
N
A
R
P
E
D
A
Site 25
Y261
R
P
E
D
A
G
L
Y
T
C
T
A
R
N
A
Site 26
S279
L
R
A
D
F
P
L
S
V
V
Q
R
E
P
A
Site 27
S292
P
A
R
D
A
A
P
S
I
P
A
P
A
E
C
Site 28
T307
L
P
D
V
Q
A
C
T
G
P
T
S
P
H
L
Site 29
S311
Q
A
C
T
G
P
T
S
P
H
L
V
L
W
H
Site 30
Y319
P
H
L
V
L
W
H
Y
D
P
Q
R
G
G
C
Site 31
Y344
A
A
R
G
F
E
T
Y
E
A
C
Q
Q
A
C
Site 32
Y377
G
W
E
P
R
W
A
Y
S
P
L
L
Q
Q
C
Site 33
T414
D
A
C
P
V
P
R
T
P
P
C
R
A
C
R
Site 34
T481
G
T
K
Y
L
E
V
T
L
S
G
M
D
W
A
Site 35
Y519
A
V
L
D
A
G
S
Y
V
R
A
A
S
E
K
Site 36
S524
G
S
Y
V
R
A
A
S
E
K
R
V
K
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation