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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CASD1
Full Name:
CAS1 domain-containing protein 1
Alias:
Type:
Mass (Da):
91680
Number AA:
797
UniProt ID:
Q96PB1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
G
K
R
E
I
N
H
Y
F
S
V
R
S
A
K
Site 2
S18
R
E
I
N
H
Y
F
S
V
R
S
A
K
V
L
Site 3
S40
L
A
A
C
H
L
A
S
R
R
Y
R
G
N
D
Site 4
Y43
C
H
L
A
S
R
R
Y
R
G
N
D
S
C
E
Site 5
S48
R
R
Y
R
G
N
D
S
C
E
Y
L
L
S
S
Site 6
Y51
R
G
N
D
S
C
E
Y
L
L
S
S
G
R
F
Site 7
S54
D
S
C
E
Y
L
L
S
S
G
R
F
L
G
E
Site 8
S55
S
C
E
Y
L
L
S
S
G
R
F
L
G
E
K
Site 9
T127
N
I
P
F
E
D
K
T
A
S
V
K
V
D
F
Site 10
S129
P
F
E
D
K
T
A
S
V
K
V
D
F
L
W
Site 11
S155
I
K
V
W
T
E
D
S
I
A
K
P
H
V
I
Site 12
S177
S
I
K
I
H
N
G
S
S
E
A
L
S
Q
Y
Site 13
S178
I
K
I
H
N
G
S
S
E
A
L
S
Q
Y
K
Site 14
S182
N
G
S
S
E
A
L
S
Q
Y
K
M
N
I
T
Site 15
Y184
S
S
E
A
L
S
Q
Y
K
M
N
I
T
S
I
Site 16
Y213
W
V
L
Q
D
P
V
Y
E
D
L
L
S
E
N
Site 17
S218
P
V
Y
E
D
L
L
S
E
N
R
K
M
I
T
Site 18
Y232
T
N
E
K
I
D
A
Y
N
E
A
A
V
S
I
Site 19
S238
A
Y
N
E
A
A
V
S
I
L
N
S
S
T
R
Site 20
S242
A
A
V
S
I
L
N
S
S
T
R
N
S
K
S
Site 21
S243
A
V
S
I
L
N
S
S
T
R
N
S
K
S
N
Site 22
S247
L
N
S
S
T
R
N
S
K
S
N
V
K
M
F
Site 23
S249
S
S
T
R
N
S
K
S
N
V
K
M
F
S
V
Site 24
S255
K
S
N
V
K
M
F
S
V
S
K
L
I
A
Q
Site 25
T264
S
K
L
I
A
Q
E
T
I
M
E
S
L
D
G
Site 26
S268
A
Q
E
T
I
M
E
S
L
D
G
L
H
L
P
Site 27
S277
D
G
L
H
L
P
E
S
S
R
E
T
T
A
M
Site 28
T281
L
P
E
S
S
R
E
T
T
A
M
I
L
M
N
Site 29
T282
P
E
S
S
R
E
T
T
A
M
I
L
M
N
V
Site 30
T345
H
R
K
N
K
P
C
T
D
L
E
S
G
E
E
Site 31
S349
K
P
C
T
D
L
E
S
G
E
E
K
K
N
I
Site 32
T359
E
K
K
N
I
I
N
T
P
V
S
S
L
E
I
Site 33
Y380
K
L
G
L
I
M
A
Y
F
Y
M
C
D
R
A
Site 34
Y382
G
L
I
M
A
Y
F
Y
M
C
D
R
A
N
L
Site 35
Y397
F
M
K
E
N
K
F
Y
T
H
S
S
F
F
I
Site 36
T398
M
K
E
N
K
F
Y
T
H
S
S
F
F
I
P
Site 37
Y515
M
D
R
P
Y
Q
F
Y
Y
F
V
P
L
V
T
Site 38
S636
G
K
G
E
P
L
F
S
N
K
I
S
N
F
L
Site 39
S659
L
T
Y
S
I
W
A
S
S
C
K
N
K
A
E
Site 40
Y691
L
I
R
N
I
P
G
Y
A
R
S
V
Y
S
S
Site 41
S694
N
I
P
G
Y
A
R
S
V
Y
S
S
F
F
A
Site 42
S790
C
G
L
L
I
L
S
S
I
Q
D
K
S
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation