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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IHPK3
Full Name:
Inositol hexakisphosphate kinase 3
Alias:
EC 2.7.4.21; Inositol hexaphosphate kinase 3; InsP6 kinase 3; IP6K3
Type:
Kinase (non-protein)
Mass (Da):
46417
Number AA:
410
UniProt ID:
Q96PC2
International Prot ID:
IPI00289690
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008440
PhosphoSite+
KinaseNET
Biological Process:
GO:0046488
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
G
H
M
S
V
M
K
Y
D
E
H
T
V
C
K
Site 2
T38
V
M
K
Y
D
E
H
T
V
C
K
P
L
V
S
Site 3
S45
T
V
C
K
P
L
V
S
R
E
Q
R
F
Y
E
Site 4
Y51
V
S
R
E
Q
R
F
Y
E
S
L
P
L
A
M
Site 5
T62
P
L
A
M
K
R
F
T
P
Q
Y
K
G
T
V
Site 6
Y65
M
K
R
F
T
P
Q
Y
K
G
T
V
T
V
H
Site 7
T68
F
T
P
Q
Y
K
G
T
V
T
V
H
L
W
K
Site 8
T70
P
Q
Y
K
G
T
V
T
V
H
L
W
K
D
S
Site 9
S82
K
D
S
T
G
H
L
S
L
V
A
N
P
V
K
Site 10
S91
V
A
N
P
V
K
E
S
Q
E
P
F
K
V
S
Site 11
S116
T
L
Q
Q
T
T
G
S
N
G
S
D
C
T
L
Site 12
T122
G
S
N
G
S
D
C
T
L
A
Q
W
P
H
A
Site 13
S134
P
H
A
Q
L
A
R
S
P
K
E
S
P
A
K
Site 14
S138
L
A
R
S
P
K
E
S
P
A
K
A
L
L
R
Site 15
T152
R
S
E
P
H
L
N
T
P
A
F
S
L
V
E
Site 16
S170
G
N
Q
V
E
R
K
S
F
N
P
W
G
L
Q
Site 17
T184
Q
C
H
Q
A
H
L
T
R
L
C
S
E
Y
P
Site 18
S188
A
H
L
T
R
L
C
S
E
Y
P
E
N
K
R
Site 19
Y190
L
T
R
L
C
S
E
Y
P
E
N
K
R
H
R
Site 20
Y208
L
E
N
V
V
S
Q
Y
T
H
P
C
V
L
D
Site 21
S228
R
Q
H
G
D
D
A
S
E
E
K
K
A
R
H
Site 22
S242
H
M
R
K
C
A
Q
S
T
S
A
C
L
G
V
Site 23
T243
M
R
K
C
A
Q
S
T
S
A
C
L
G
V
R
Site 24
S244
R
K
C
A
Q
S
T
S
A
C
L
G
V
R
I
Site 25
Y257
R
I
C
G
M
Q
V
Y
Q
T
D
K
K
Y
F
Site 26
Y263
V
Y
Q
T
D
K
K
Y
F
L
C
K
D
K
Y
Site 27
Y270
Y
F
L
C
K
D
K
Y
Y
G
R
K
L
S
V
Site 28
Y271
F
L
C
K
D
K
Y
Y
G
R
K
L
S
V
E
Site 29
S276
K
Y
Y
G
R
K
L
S
V
E
G
F
R
Q
A
Site 30
Y285
E
G
F
R
Q
A
L
Y
Q
F
L
H
N
G
S
Site 31
S292
Y
Q
F
L
H
N
G
S
H
L
R
R
E
L
L
Site 32
S311
H
Q
L
R
A
L
L
S
V
I
R
S
Q
S
S
Site 33
S315
A
L
L
S
V
I
R
S
Q
S
S
Y
R
F
Y
Site 34
S317
L
S
V
I
R
S
Q
S
S
Y
R
F
Y
S
S
Site 35
S318
S
V
I
R
S
Q
S
S
Y
R
F
Y
S
S
S
Site 36
Y319
V
I
R
S
Q
S
S
Y
R
F
Y
S
S
S
L
Site 37
Y322
S
Q
S
S
Y
R
F
Y
S
S
S
L
L
V
I
Site 38
S323
Q
S
S
Y
R
F
Y
S
S
S
L
L
V
I
Y
Site 39
S325
S
Y
R
F
Y
S
S
S
L
L
V
I
Y
D
G
Site 40
Y330
S
S
S
L
L
V
I
Y
D
G
Q
E
P
P
E
Site 41
S342
P
P
E
R
A
P
G
S
P
H
P
H
E
A
P
Site 42
S355
A
P
Q
A
A
H
G
S
S
P
G
G
L
T
K
Site 43
S356
P
Q
A
A
H
G
S
S
P
G
G
L
T
K
V
Site 44
Y385
Y
W
N
E
H
T
T
Y
D
G
P
D
P
G
Y
Site 45
Y392
Y
D
G
P
D
P
G
Y
I
F
G
L
E
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation