PhosphoNET

           
Protein Info 
   
Short Name:  DGAT2
Full Name:  Diacylglycerol O-acyltransferase 2
Alias:  Diglyceride acyltransferase 2; EC 2.3.1.20; HMFN1045
Type:  Membrane, Membrane fraction, Endoplasmic reticulum, Endoplasmic reticulum membrane, Integral membrane protein
Mass (Da):  43831
Number AA:  388
UniProt ID:  Q96PD7
International Prot ID:  IPI00176376
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0016021  GO:0005624 Uniprot OncoNet
Molecular Function:  GO:0004144     PhosphoSite+ KinaseNET
Biological Process:  GO:0006071  GO:0019432   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9KTLIAAYSGVLRGER
Site 2S23RQAEADRSQRSHGGP
Site 3S26EADRSQRSHGGPALS
Site 4S33SHGGPALSREGSGRW
Site 5S37PALSREGSGRWGTGS
Site 6T42EGSGRWGTGSSILSA
Site 7S44SGRWGTGSSILSALQ
Site 8S45GRWGTGSSILSALQD
Site 9S55SALQDLFSVTWLNRS
Site 10T116WLVFDWNTPKKGGRR
Site 11S124PKKGGRRSQWVRNWA
Site 12Y139VWRYFRDYFPIQLVK
Site 13T152VKTHNLLTTRNYIFG
Site 14Y156NLLTTRNYIFGYHPH
Site 15T179CNFSTEATEVSKKFP
Site 16Y207RMPVLREYLMSGGIC
Site 17S217SGGICPVSRDTIDYL
Site 18Y223VSRDTIDYLLSKNGS
Site 19S226DTIDYLLSKNGSGNA
Site 20S246GGAAESLSSMPGKNA
Site 21S247GAAESLSSMPGKNAV
Site 22T255MPGKNAVTLRNRKGF
Site 23Y285SFGENEVYKQVIFEE
Site 24S322HGRGLFSSDTWGLVP
Site 25T324RGLFSSDTWGLVPYS
Site 26Y330DTWGLVPYSKPITTV
Site 27T336PYSKPITTVVGEPIT
Site 28T343TVVGEPITIPKLEHP
Site 29Y358TQQDIDLYHTMYMEA
Site 30T375KLFDKHKTKFGLPET
Site 31T382TKFGLPETEVLEVN_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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