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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR124
Full Name:
Probable G-protein coupled receptor 124
Alias:
DKFZp434C211; DKFZp434J0911; FLJ14390; G protein-coupled receptor 124; GP124; G-protein coupled receptor 124; KIAA1531; TEM5; Tumor endothelial marker 5
Type:
Mass (Da):
142650
Number AA:
UniProt ID:
Q96PE1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007218
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S40
G
A
P
G
C
P
L
S
I
R
S
C
K
C
S
Site 2
S43
G
C
P
L
S
I
R
S
C
K
C
S
G
E
R
Site 3
S47
S
I
R
S
C
K
C
S
G
E
R
P
K
G
L
Site 4
S55
G
E
R
P
K
G
L
S
G
G
V
P
G
P
A
Site 5
S69
A
R
R
R
V
V
C
S
G
G
D
L
P
E
P
Site 6
S121
D
L
R
N
N
I
I
S
T
V
Q
P
G
A
F
Site 7
S140
E
L
K
R
L
D
L
S
N
N
R
I
G
C
L
Site 8
T148
N
N
R
I
G
C
L
T
S
E
T
F
Q
G
L
Site 9
S149
N
R
I
G
C
L
T
S
E
T
F
Q
G
L
P
Site 10
S209
L
P
W
A
Q
N
R
S
L
Q
L
S
E
H
T
Site 11
S213
Q
N
R
S
L
Q
L
S
E
H
T
L
C
A
Y
Site 12
T216
S
L
Q
L
S
E
H
T
L
C
A
Y
P
S
A
Site 13
Y220
S
E
H
T
L
C
A
Y
P
S
A
L
H
A
Q
Site 14
S253
H
T
H
H
L
I
P
S
L
R
Q
V
V
F
Q
Site 15
S269
D
R
L
P
F
Q
C
S
A
S
Y
L
G
N
D
Site 16
Y282
N
D
T
R
I
R
W
Y
H
N
R
A
P
V
E
Site 17
T370
G
D
F
R
W
P
R
T
L
A
G
I
T
A
Y
Site 18
Y377
T
L
A
G
I
T
A
Y
Q
S
C
L
Q
Y
P
Site 19
S379
A
G
I
T
A
Y
Q
S
C
L
Q
Y
P
F
T
Site 20
T397
L
G
G
G
A
P
G
T
R
A
S
R
R
C
D
Site 21
S400
G
A
P
G
T
R
A
S
R
R
C
D
R
A
G
Site 22
Y414
G
R
W
E
P
G
D
Y
S
H
C
L
Y
T
N
Site 23
Y419
G
D
Y
S
H
C
L
Y
T
N
D
I
T
R
V
Site 24
T451
A
H
Q
L
R
V
Y
T
A
E
A
A
S
F
S
Site 25
S528
R
I
G
G
A
A
L
S
P
H
A
Q
H
I
S
Site 26
Y546
R
N
V
A
L
E
A
Y
L
I
K
P
H
S
Y
Site 27
T557
P
H
S
Y
V
G
L
T
C
T
A
F
Q
R
R
Site 28
T571
R
E
G
G
V
P
G
T
R
P
G
S
P
G
Q
Site 29
S575
V
P
G
T
R
P
G
S
P
G
Q
N
P
P
P
Site 30
T597
Q
Q
L
R
F
R
C
T
T
G
R
P
N
V
S
Site 31
T598
Q
L
R
F
R
C
T
T
G
R
P
N
V
S
L
Site 32
S604
T
T
G
R
P
N
V
S
L
S
S
F
H
I
K
Site 33
S606
G
R
P
N
V
S
L
S
S
F
H
I
K
N
S
Site 34
S607
R
P
N
V
S
L
S
S
F
H
I
K
N
S
V
Site 35
S656
R
N
G
R
L
F
H
S
H
S
N
T
S
R
P
Site 36
S658
G
R
L
F
H
S
H
S
N
T
S
R
P
G
A
Site 37
T660
L
F
H
S
H
S
N
T
S
R
P
G
A
A
G
Site 38
S661
F
H
S
H
S
N
T
S
R
P
G
A
A
G
P
Site 39
S698
L
T
E
P
V
A
V
S
L
R
H
W
A
E
G
Site 40
S714
E
P
V
A
A
W
W
S
Q
E
G
P
G
E
A
Site 41
S726
G
E
A
G
G
W
T
S
E
G
C
Q
L
R
S
Site 42
S733
S
E
G
C
Q
L
R
S
S
Q
P
N
V
S
A
Site 43
S734
E
G
C
Q
L
R
S
S
Q
P
N
V
S
A
L
Site 44
S739
R
S
S
Q
P
N
V
S
A
L
H
C
Q
H
L
Site 45
S796
I
T
Y
I
L
N
H
S
S
I
R
V
S
R
K
Site 46
S797
T
Y
I
L
N
H
S
S
I
R
V
S
R
K
G
Site 47
T865
R
V
L
H
K
E
L
T
W
R
A
P
P
P
Q
Site 48
T880
E
G
D
P
A
L
P
T
P
S
P
M
L
R
F
Site 49
S882
D
P
A
L
P
T
P
S
P
M
L
R
F
Y
L
Site 50
Y910
A
A
V
N
I
H
N
Y
R
D
H
S
P
Y
C
Site 51
S966
K
A
G
N
S
R
A
S
L
E
A
G
E
E
L
Site 52
S976
A
G
E
E
L
R
G
S
T
R
L
R
G
S
G
Site 53
T977
G
E
E
L
R
G
S
T
R
L
R
G
S
G
P
Site 54
S982
G
S
T
R
L
R
G
S
G
P
L
L
S
D
S
Site 55
S987
R
G
S
G
P
L
L
S
D
S
G
S
L
L
A
Site 56
T995
D
S
G
S
L
L
A
T
G
S
A
R
V
G
T
Site 57
T1002
T
G
S
A
R
V
G
T
P
G
P
P
E
D
G
Site 58
S1011
G
P
P
E
D
G
D
S
L
Y
S
P
G
V
Q
Site 59
Y1013
P
E
D
G
D
S
L
Y
S
P
G
V
Q
L
G
Site 60
S1014
E
D
G
D
S
L
Y
S
P
G
V
Q
L
G
A
Site 61
S1079
R
R
R
D
V
R
A
S
W
R
A
C
C
P
P
Site 62
S1088
R
A
C
C
P
P
A
S
P
A
A
P
H
A
P
Site 63
S1107
P
A
A
A
E
D
G
S
P
V
F
G
E
G
P
Site 64
S1116
V
F
G
E
G
P
P
S
L
K
S
S
P
S
G
Site 65
S1119
E
G
P
P
S
L
K
S
S
P
S
G
S
S
G
Site 66
S1120
G
P
P
S
L
K
S
S
P
S
G
S
S
G
H
Site 67
S1122
P
S
L
K
S
S
P
S
G
S
S
G
H
P
L
Site 68
S1124
L
K
S
S
P
S
G
S
S
G
H
P
L
A
L
Site 69
S1125
K
S
S
P
S
G
S
S
G
H
P
L
A
L
G
Site 70
S1144
T
N
L
Q
L
A
Q
S
Q
V
C
E
A
G
A
Site 71
T1164
G
E
P
E
P
A
G
T
R
G
N
L
A
H
R
Site 72
S1185
H
G
R
R
A
H
K
S
R
A
K
G
H
R
A
Site 73
S1217
G
A
L
E
L
L
S
S
E
S
G
S
L
H
N
Site 74
S1219
L
E
L
L
S
S
E
S
G
S
L
H
N
S
P
Site 75
S1221
L
L
S
S
E
S
G
S
L
H
N
S
P
T
D
Site 76
S1225
E
S
G
S
L
H
N
S
P
T
D
S
Y
L
G
Site 77
T1227
G
S
L
H
N
S
P
T
D
S
Y
L
G
S
S
Site 78
S1229
L
H
N
S
P
T
D
S
Y
L
G
S
S
R
N
Site 79
Y1230
H
N
S
P
T
D
S
Y
L
G
S
S
R
N
S
Site 80
S1233
P
T
D
S
Y
L
G
S
S
R
N
S
P
G
A
Site 81
S1234
T
D
S
Y
L
G
S
S
R
N
S
P
G
A
G
Site 82
S1237
Y
L
G
S
S
R
N
S
P
G
A
G
L
Q
L
Site 83
T1251
L
E
G
E
P
M
L
T
P
S
E
G
S
D
T
Site 84
S1253
G
E
P
M
L
T
P
S
E
G
S
D
T
S
A
Site 85
T1258
T
P
S
E
G
S
D
T
S
A
A
P
L
S
E
Site 86
S1259
P
S
E
G
S
D
T
S
A
A
P
L
S
E
A
Site 87
S1264
D
T
S
A
A
P
L
S
E
A
G
R
A
G
Q
Site 88
S1274
G
R
A
G
Q
R
R
S
A
S
R
D
S
L
K
Site 89
S1276
A
G
Q
R
R
S
A
S
R
D
S
L
K
G
G
Site 90
S1279
R
R
S
A
S
R
D
S
L
K
G
G
G
A
L
Site 91
S1290
G
G
A
L
E
K
E
S
H
R
R
S
Y
P
L
Site 92
S1294
E
K
E
S
H
R
R
S
Y
P
L
N
A
A
S
Site 93
Y1295
K
E
S
H
R
R
S
Y
P
L
N
A
A
S
L
Site 94
S1301
S
Y
P
L
N
A
A
S
L
N
G
A
P
K
G
Site 95
Y1311
G
A
P
K
G
G
K
Y
D
D
V
T
L
M
G
Site 96
T1315
G
G
K
Y
D
D
V
T
L
M
G
A
E
V
A
Site 97
T1329
A
S
G
G
C
M
K
T
G
L
W
K
S
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation