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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TGM7
Full Name:
Protein-glutamine gamma-glutamyltransferase Z
Alias:
EC 2.3.2.13; Protein-glutamine gamma-glutamyltransferase Z
Type:
Transferase
Mass (Da):
79941
Number AA:
710
UniProt ID:
Q96PF1
International Prot ID:
IPI00044409
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008415
GO:0005509
GO:0003810
PhosphoSite+
KinaseNET
Biological Process:
GO:0018149
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
D
Q
V
A
T
L
R
L
E
S
V
D
Site 2
S11
V
A
T
L
R
L
E
S
V
D
L
Q
S
S
R
Site 3
S16
L
E
S
V
D
L
Q
S
S
R
N
N
K
E
H
Site 4
S17
E
S
V
D
L
Q
S
S
R
N
N
K
E
H
H
Site 5
T25
R
N
N
K
E
H
H
T
Q
E
M
G
V
K
R
Site 6
T34
E
M
G
V
K
R
L
T
V
R
R
G
Q
P
F
Site 7
Y42
V
R
R
G
Q
P
F
Y
L
R
L
S
F
S
R
Site 8
S46
Q
P
F
Y
L
R
L
S
F
S
R
P
F
Q
S
Site 9
S48
F
Y
L
R
L
S
F
S
R
P
F
Q
S
Q
N
Site 10
S53
S
F
S
R
P
F
Q
S
Q
N
D
H
I
T
F
Site 11
T59
Q
S
Q
N
D
H
I
T
F
V
A
E
T
G
P
Site 12
S90
V
Q
P
G
N
V
W
S
A
S
D
F
T
I
D
Site 13
S92
P
G
N
V
W
S
A
S
D
F
T
I
D
S
N
Site 14
T95
V
W
S
A
S
D
F
T
I
D
S
N
S
L
Q
Site 15
S98
A
S
D
F
T
I
D
S
N
S
L
Q
V
S
L
Site 16
S104
D
S
N
S
L
Q
V
S
L
F
T
P
A
N
A
Site 17
Y116
A
N
A
V
I
G
H
Y
T
L
K
I
E
I
S
Site 18
T117
N
A
V
I
G
H
Y
T
L
K
I
E
I
S
Q
Site 19
S123
Y
T
L
K
I
E
I
S
Q
G
Q
G
H
S
V
Site 20
S129
I
S
Q
G
Q
G
H
S
V
T
Y
P
L
G
T
Site 21
T131
Q
G
Q
G
H
S
V
T
Y
P
L
G
T
F
I
Site 22
Y151
W
S
P
E
D
D
V
Y
L
P
S
E
I
L
L
Site 23
Y161
S
E
I
L
L
Q
E
Y
I
M
R
D
Y
G
F
Site 24
Y166
Q
E
Y
I
M
R
D
Y
G
F
V
Y
K
G
H
Site 25
Y204
E
I
L
N
K
S
L
Y
H
L
K
N
P
A
K
Site 26
S214
K
N
P
A
K
D
C
S
Q
R
N
D
V
V
Y
Site 27
S227
V
Y
V
C
R
V
V
S
A
M
I
N
S
N
D
Site 28
Y247
Q
G
N
W
G
E
D
Y
S
K
G
V
S
P
L
Site 29
S248
G
N
W
G
E
D
Y
S
K
G
V
S
P
L
E
Site 30
S252
E
D
Y
S
K
G
V
S
P
L
E
W
K
G
S
Site 31
S259
S
P
L
E
W
K
G
S
V
A
I
L
Q
Q
W
Site 32
S267
V
A
I
L
Q
Q
W
S
A
R
G
G
Q
P
V
Site 33
Y276
R
G
G
Q
P
V
K
Y
G
Q
C
W
V
F
A
Site 34
S301
G
V
P
T
R
V
V
S
N
F
R
S
A
H
N
Site 35
S305
R
V
V
S
N
F
R
S
A
H
N
V
D
R
N
Site 36
T314
H
N
V
D
R
N
L
T
I
D
T
Y
Y
D
R
Site 37
Y318
R
N
L
T
I
D
T
Y
Y
D
R
N
A
E
M
Site 38
Y319
N
L
T
I
D
T
Y
Y
D
R
N
A
E
M
L
Site 39
T328
R
N
A
E
M
L
S
T
Q
K
R
D
K
I
W
Site 40
Y354
R
K
D
L
P
P
G
Y
N
G
W
Q
V
L
D
Site 41
T363
G
W
Q
V
L
D
P
T
P
Q
Q
T
S
S
G
Site 42
Y391
E
G
D
V
H
L
A
Y
D
T
P
F
V
Y
A
Site 43
Y397
A
Y
D
T
P
F
V
Y
A
E
V
N
A
D
E
Site 44
S423
E
I
L
A
H
N
T
S
S
I
G
K
E
I
S
Site 45
S430
S
S
I
G
K
E
I
S
T
K
M
V
G
S
D
Site 46
T431
S
I
G
K
E
I
S
T
K
M
V
G
S
D
Q
Site 47
S436
I
S
T
K
M
V
G
S
D
Q
R
Q
S
I
T
Site 48
S441
V
G
S
D
Q
R
Q
S
I
T
S
S
Y
K
Y
Site 49
S444
D
Q
R
Q
S
I
T
S
S
Y
K
Y
P
E
G
Site 50
S445
Q
R
Q
S
I
T
S
S
Y
K
Y
P
E
G
S
Site 51
Y446
R
Q
S
I
T
S
S
Y
K
Y
P
E
G
S
P
Site 52
Y448
S
I
T
S
S
Y
K
Y
P
E
G
S
P
E
E
Site 53
S452
S
Y
K
Y
P
E
G
S
P
E
E
R
A
V
F
Site 54
S482
P
F
L
D
L
L
E
S
G
G
L
R
D
Q
P
Site 55
S518
R
I
Q
R
V
P
D
S
T
H
P
R
G
P
I
Site 56
T519
I
Q
R
V
P
D
S
T
H
P
R
G
P
I
G
Site 57
T542
A
L
L
H
G
G
G
T
Q
K
P
F
W
R
H
Site 58
T561
N
L
D
F
G
K
E
T
Q
W
P
L
L
L
P
Site 59
S570
W
P
L
L
L
P
Y
S
N
Y
R
N
K
L
T
Site 60
T577
S
N
Y
R
N
K
L
T
D
E
K
L
I
R
V
Site 61
S585
D
E
K
L
I
R
V
S
G
I
A
E
V
E
E
Site 62
S611
C
L
E
P
P
H
L
S
I
E
V
S
E
R
A
Site 63
S615
P
H
L
S
I
E
V
S
E
R
A
E
V
G
K
Site 64
S648
C
T
M
V
L
E
G
S
G
L
I
N
G
Q
I
Site 65
T667
G
T
L
V
A
G
H
T
L
Q
I
Q
L
D
L
Site 66
Y675
L
Q
I
Q
L
D
L
Y
P
T
K
A
G
P
R
Site 67
T677
I
Q
L
D
L
Y
P
T
K
A
G
P
R
Q
L
Site 68
S689
R
Q
L
Q
V
L
I
S
S
N
E
V
K
E
I
Site 69
Y699
E
V
K
E
I
K
G
Y
K
D
I
F
V
T
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation