KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GBP5
Full Name:
Guanylate-binding protein 5
Alias:
GBP-TA antigen;GTP-binding protein 5;Guanine nucleotide-binding protein 5
Type:
Mass (Da):
66617
Number AA:
586
UniProt ID:
Q96PP8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
G
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
Site 2
Y53
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
G
Site 3
S66
A
G
K
N
K
G
F
S
V
A
S
T
V
Q
S
Site 4
T70
K
G
F
S
V
A
S
T
V
Q
S
H
T
K
G
Site 5
S157
D
L
L
K
A
R
N
S
P
D
L
D
R
V
E
Site 6
S169
R
V
E
D
P
A
D
S
A
S
F
F
P
D
L
Site 7
S171
E
D
P
A
D
S
A
S
F
F
P
D
L
V
W
Site 8
T195
E
I
D
G
Q
L
V
T
P
D
E
Y
L
E
N
Site 9
Y199
Q
L
V
T
P
D
E
Y
L
E
N
S
L
R
P
Site 10
S203
P
D
E
Y
L
E
N
S
L
R
P
K
Q
G
S
Site 11
S210
S
L
R
P
K
Q
G
S
D
Q
R
V
Q
N
F
Site 12
S275
C
S
Y
I
F
S
H
S
M
T
K
T
L
P
G
Site 13
S323
A
L
A
Q
R
E
N
S
A
A
V
Q
K
A
I
Site 14
Y333
V
Q
K
A
I
A
H
Y
D
Q
Q
M
G
Q
K
Site 15
S358
L
L
D
L
H
R
T
S
E
R
E
A
I
E
V
Site 16
S370
I
E
V
F
M
K
N
S
F
K
D
V
D
Q
S
Site 17
S377
S
F
K
D
V
D
Q
S
F
Q
K
E
L
E
T
Site 18
S401
C
K
R
N
L
E
A
S
S
D
Y
C
S
A
L
Site 19
S402
K
R
N
L
E
A
S
S
D
Y
C
S
A
L
L
Site 20
Y404
N
L
E
A
S
S
D
Y
C
S
A
L
L
K
D
Site 21
S406
E
A
S
S
D
Y
C
S
A
L
L
K
D
I
F
Site 22
Y425
E
A
V
K
Q
G
I
Y
S
K
P
G
G
H
N
Site 23
S426
A
V
K
Q
G
I
Y
S
K
P
G
G
H
N
L
Site 24
T438
H
N
L
F
I
Q
K
T
E
E
L
K
A
K
Y
Site 25
Y445
T
E
E
L
K
A
K
Y
Y
R
E
P
R
K
G
Site 26
Y446
E
E
L
K
A
K
Y
Y
R
E
P
R
K
G
I
Site 27
Y462
A
E
E
V
L
Q
K
Y
L
K
S
K
E
S
V
Site 28
S465
V
L
Q
K
Y
L
K
S
K
E
S
V
S
H
A
Site 29
S468
K
Y
L
K
S
K
E
S
V
S
H
A
I
L
Q
Site 30
T558
Q
A
A
Q
L
S
T
T
F
Q
A
Q
N
R
S
Site 31
S565
T
F
Q
A
Q
N
R
S
L
L
S
E
L
Q
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation