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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FMNL2
Full Name:
Formin-like protein 2
Alias:
FHOD2; Formin 2 domain-containing 2; Formin homology 2 domain-containing protein 2; Formin-like 2; KIAA1902
Type:
Cytoskeletal protein
Mass (Da):
123321
Number AA:
1086
UniProt ID:
Q96PY5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0017048
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
G
N
A
G
S
M
D
S
Q
Q
T
D
F
R
A
Site 2
Y55
K
A
R
L
L
R
Q
Y
D
N
E
K
K
W
E
Site 3
T78
Q
V
K
N
P
P
H
T
Y
I
Q
K
L
K
G
Site 4
Y86
Y
I
Q
K
L
K
G
Y
L
D
P
A
V
T
R
Site 5
S103
F
R
R
R
V
Q
E
S
T
Q
V
L
R
E
L
Site 6
T104
R
R
R
V
Q
E
S
T
Q
V
L
R
E
L
E
Site 7
S113
V
L
R
E
L
E
I
S
L
R
T
N
H
I
G
Site 8
S153
A
V
T
F
D
F
E
S
V
E
S
T
V
E
S
Site 9
S156
F
D
F
E
S
V
E
S
T
V
E
S
S
V
D
Site 10
T157
D
F
E
S
V
E
S
T
V
E
S
S
V
D
K
Site 11
S160
S
V
E
S
T
V
E
S
S
V
D
K
S
K
P
Site 12
S161
V
E
S
T
V
E
S
S
V
D
K
S
K
P
W
Site 13
S165
V
E
S
S
V
D
K
S
K
P
W
S
R
S
I
Site 14
S169
V
D
K
S
K
P
W
S
R
S
I
E
D
L
H
Site 15
S171
K
S
K
P
W
S
R
S
I
E
D
L
H
R
G
Site 16
S179
I
E
D
L
H
R
G
S
N
L
P
S
P
V
G
Site 17
S183
H
R
G
S
N
L
P
S
P
V
G
N
S
V
S
Site 18
S188
L
P
S
P
V
G
N
S
V
S
R
S
G
R
H
Site 19
S190
S
P
V
G
N
S
V
S
R
S
G
R
H
S
A
Site 20
S192
V
G
N
S
V
S
R
S
G
R
H
S
A
L
R
Site 21
S196
V
S
R
S
G
R
H
S
A
L
R
Y
N
T
L
Site 22
T202
H
S
A
L
R
Y
N
T
L
P
S
R
R
T
L
Site 23
S205
L
R
Y
N
T
L
P
S
R
R
T
L
K
N
S
Site 24
T208
N
T
L
P
S
R
R
T
L
K
N
S
R
L
V
Site 25
S212
S
R
R
T
L
K
N
S
R
L
V
S
K
K
D
Site 26
S216
L
K
N
S
R
L
V
S
K
K
D
D
V
H
V
Site 27
Y234
C
L
R
A
I
M
N
Y
Q
Y
G
F
N
M
V
Site 28
Y236
R
A
I
M
N
Y
Q
Y
G
F
N
M
V
M
S
Site 29
S254
A
V
N
E
I
A
L
S
L
N
N
K
N
P
R
Site 30
S285
G
G
H
E
I
I
L
S
A
F
D
N
F
K
E
Site 31
Y342
N
F
R
V
H
L
Q
Y
E
F
T
K
L
G
L
Site 32
Y352
T
K
L
G
L
D
E
Y
L
D
K
L
K
H
T
Site 33
S361
D
K
L
K
H
T
E
S
D
K
L
Q
V
Q
I
Site 34
T387
A
L
L
E
D
A
E
T
K
N
A
A
L
E
R
Site 35
S403
E
E
L
E
E
N
I
S
H
L
S
E
K
L
Q
Site 36
T412
L
S
E
K
L
Q
D
T
E
N
E
A
M
S
K
Site 37
S418
D
T
E
N
E
A
M
S
K
I
V
E
L
E
K
Site 38
Y441
L
D
V
V
R
E
I
Y
K
D
A
N
T
Q
V
Site 39
T446
E
I
Y
K
D
A
N
T
Q
V
H
T
L
R
K
Site 40
S466
E
E
A
I
Q
R
Q
S
T
L
E
K
K
I
H
Site 41
T467
E
A
I
Q
R
Q
S
T
L
E
K
K
I
H
E
Site 42
T480
H
E
L
E
K
Q
G
T
I
K
I
Q
K
K
G
Site 43
T517
A
G
N
S
V
G
P
T
M
G
A
A
S
S
G
Site 44
S522
G
P
T
M
G
A
A
S
S
G
P
L
P
P
P
Site 45
S523
P
T
M
G
A
A
S
S
G
P
L
P
P
P
P
Site 46
S536
P
P
P
P
L
P
P
S
S
D
T
P
E
T
V
Site 47
S537
P
P
P
L
P
P
S
S
D
T
P
E
T
V
Q
Site 48
T539
P
L
P
P
S
S
D
T
P
E
T
V
Q
N
G
Site 49
T542
P
S
S
D
T
P
E
T
V
Q
N
G
P
V
T
Site 50
T549
T
V
Q
N
G
P
V
T
P
P
M
P
P
P
P
Site 51
S602
P
P
L
P
G
T
S
S
P
T
V
V
F
N
S
Site 52
T622
K
I
K
K
P
I
K
T
K
F
R
M
P
V
F
Site 53
T642
K
P
N
Q
I
N
G
T
V
F
N
E
I
D
D
Site 54
T667
E
F
E
E
I
F
K
T
K
A
Q
G
P
A
I
Site 55
S677
Q
G
P
A
I
D
L
S
S
S
K
Q
K
I
P
Site 56
S679
P
A
I
D
L
S
S
S
K
Q
K
I
P
Q
K
Site 57
T692
Q
K
G
S
N
K
V
T
L
L
E
A
N
R
A
Site 58
T705
R
A
K
N
L
A
I
T
L
R
K
A
G
K
T
Site 59
T712
T
L
R
K
A
G
K
T
A
D
E
I
C
K
A
Site 60
Y752
E
V
K
V
L
R
L
Y
E
R
E
R
K
P
L
Site 61
S763
R
K
P
L
E
N
L
S
D
E
D
R
F
M
M
Site 62
T799
A
E
S
I
Q
M
L
T
P
Q
L
H
A
I
I
Site 63
S815
A
S
V
S
I
K
S
S
Q
K
L
K
K
I
L
Site 64
Y831
I
I
L
A
L
G
N
Y
M
N
S
S
K
R
G
Site 65
S834
A
L
G
N
Y
M
N
S
S
K
R
G
A
V
Y
Site 66
S835
L
G
N
Y
M
N
S
S
K
R
G
A
V
Y
G
Site 67
Y841
S
S
K
R
G
A
V
Y
G
F
K
L
Q
S
L
Site 68
T854
S
L
D
L
L
L
D
T
K
S
T
D
R
K
Q
Site 69
S856
D
L
L
L
D
T
K
S
T
D
R
K
Q
T
L
Site 70
T857
L
L
L
D
T
K
S
T
D
R
K
Q
T
L
L
Site 71
T862
K
S
T
D
R
K
Q
T
L
L
H
Y
I
S
N
Site 72
Y866
R
K
Q
T
L
L
H
Y
I
S
N
V
V
K
E
Site 73
S868
Q
T
L
L
H
Y
I
S
N
V
V
K
E
K
Y
Site 74
Y875
S
N
V
V
K
E
K
Y
H
Q
V
S
L
F
Y
Site 75
Y882
Y
H
Q
V
S
L
F
Y
N
E
L
H
Y
V
E
Site 76
T913
L
Q
R
G
M
D
L
T
K
R
E
Y
T
M
H
Site 77
Y917
M
D
L
T
K
R
E
Y
T
M
H
D
H
N
T
Site 78
T918
D
L
T
K
R
E
Y
T
M
H
D
H
N
T
L
Site 79
T924
Y
T
M
H
D
H
N
T
L
L
K
E
F
I
L
Site 80
Y957
A
F
D
D
V
V
K
Y
F
G
E
N
P
K
T
Site 81
T964
Y
F
G
E
N
P
K
T
T
P
P
S
V
F
F
Site 82
T965
F
G
E
N
P
K
T
T
P
P
S
V
F
F
P
Site 83
Y981
F
V
R
F
V
K
A
Y
K
Q
A
E
E
E
N
Site 84
S1016
M
E
Q
Q
D
P
K
S
P
S
H
K
S
K
R
Site 85
S1018
Q
Q
D
P
K
S
P
S
H
K
S
K
R
Q
Q
Site 86
S1021
P
K
S
P
S
H
K
S
K
R
Q
Q
Q
E
L
Site 87
Y1044
V
K
D
N
R
H
V
Y
E
G
K
D
G
A
I
Site 88
T1067
T
V
P
F
T
A
R
T
A
K
R
G
S
R
F
Site 89
S1072
A
R
T
A
K
R
G
S
R
F
F
C
E
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation